Cas no 70298-89-4 (2,2-dimethyl-N-(pyridin-4-yl)propanamide)

2,2-Dimethyl-N-(pyridin-4-yl)propanamide is a specialized organic compound featuring a pyridine moiety linked to a dimethyl-substituted propanamide group. Its structural design offers stability and reactivity, making it valuable in pharmaceutical and agrochemical research as a key intermediate or building block. The pyridine ring enhances its potential for hydrogen bonding and coordination, while the sterically hindered amide group contributes to controlled reactivity. This compound is particularly useful in the synthesis of biologically active molecules, where its distinct framework can influence solubility and binding properties. High purity grades ensure consistency in experimental and industrial applications.
2,2-dimethyl-N-(pyridin-4-yl)propanamide structure
70298-89-4 structure
Product Name:2,2-dimethyl-N-(pyridin-4-yl)propanamide
CAS No:70298-89-4
MF:C10H14N2O
MW:178.230962276459
MDL:MFCD00996248
CID:576729
PubChem ID:427059
Update Time:2025-05-22

2,2-dimethyl-N-(pyridin-4-yl)propanamide Chemical and Physical Properties

Names and Identifiers

    • 2,2-Dimethyl-N-pyridin-4-yl-propionamide
    • 4-(2,2,2-Trimethylacetamido)pyridine
    • N-(4-Pyridyl)pivalamide
    • 2,2-DIMETHYL-N-(4-PYRIDINYL)PROPANAMIDE
    • 2,2-dimethyl-N-pyridin-4-ylpropanamide
    • Propanamide,2,2-dimethyl-N-4-pyridinyl-
    • 2,2-Dimethyl-N-(4-pyridyl)propionamide
    • 2,2-Dimethyl-N-pyridin-4-ylpropionamide
    • 2,2-dimethyl-N-(pyridin-4-yl)propanamide
    • CHEBI:194715
    • IDI1_015794
    • AR2618
    • TS-02487
    • JCMMVFHXRDNILC-UHFFFAOYSA-N
    • 4-trimethylacetamido pyridine
    • Maybridge3_004407
    • AC-25631
    • AM85881
    • 2,2-dimethyl-N-(4-pyridyl)propanamide;2,2-Dimethyl-N-(4-pyridinyl)propanamide
    • 2,2-dimethyl-N-(4-pyridinyl)propanamide, 2b
    • P2044
    • Z255129520
    • AB07936
    • DTXSID90330146
    • 2,2-Dimethyl-N-pyridin-4-yl-propionamide, AldrichCPR
    • CS-W017312
    • SY014267
    • BDBM84612
    • VCA29889
    • 70298-89-4
    • HMS1443I07
    • 2,2-DIMETHYL-N-(PYRIDIN-4-YL)-PROPIONAMIDE
    • 4-pivaloylaminopyridine
    • AKOS003860392
    • MFCD00996248
    • A836838
    • J-506829
    • EN300-133467
    • N-(Pyridin-4-yl)pivalamide
    • 4-trimethylacetamidopyridine
    • FT-0609276
    • SCHEMBL334744
    • BBL104295
    • STL558582
    • MDL： MFCD00996248
    • Inchi： 1S/C10H14N2O/c1-10(2,3)9(13)12-8-4-6-11-7-5-8/h4-7H,1-3H3,(H,11,12,13)
    • InChI Key： JCMMVFHXRDNILC-UHFFFAOYSA-N
    • SMILES： O=C(C(C)(C)C)NC1C=CN=CC=1

Computed Properties

  • Exact Mass: 178.11100
  • Monoisotopic Mass: 178.110613074 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 2
  • Complexity: 178
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 3
  • XLogP3: nothing
  • Molecular Weight: 178.23
  • Topological Polar Surface Area: 42?2

Experimental Properties

  • Melting Point: 131.0 to 135.0 deg-C
  • Boiling Point: 349.3℃ at 760 mmHg
  • PSA: 41.99000
  • LogP: 2.13920

2,2-dimethyl-N-(pyridin-4-yl)propanamide Security Information

  • Signal Word：Warning
  • Hazard Statement： H302
  • Warning Statement： P261;P280;P302+P352;P305+P351+P338
  • Hazard Category Code： 22
  • Safety Instruction： S26-S37/39
  • Hazardous Material Identification： Xi
  • Risk Phrases：R36/37/38
  • HazardClass：IRRITANT
  • Storage Condition：Room temperature
  • Safety Term：S26;S37/39

2,2-dimethyl-N-(pyridin-4-yl)propanamide Customs Data

  • HS CODE：2933399090
  • Customs Data：

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2,2-dimethyl-N-(pyridin-4-yl)propanamide Pricemore >>

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2,2-dimethyl-N-(pyridin-4-yl)propanamide Production Method

2,2-dimethyl-N-(pyridin-4-yl)propanamide Related Literature

Related Categories

Additional information on 2,2-dimethyl-N-(pyridin-4-yl)propanamide

Recent Advances in the Study of 2,2-dimethyl-N-(pyridin-4-yl)propanamide (CAS: 70298-89-4) in Chemical Biology and Pharmaceutical Research

The compound 2,2-dimethyl-N-(pyridin-4-yl)propanamide (CAS: 70298-89-4) has recently garnered significant attention in the field of chemical biology and pharmaceutical research. This molecule, characterized by its unique structural features, has been the subject of numerous studies aimed at exploring its potential applications in drug discovery and development. Recent literature highlights its role as a key intermediate in the synthesis of biologically active compounds, particularly those targeting neurological and inflammatory disorders.

One of the most notable studies published in the past year investigated the pharmacokinetic properties of 2,2-dimethyl-N-(pyridin-4-yl)propanamide. Researchers employed advanced analytical techniques, including high-performance liquid chromatography (HPLC) and mass spectrometry, to evaluate its stability, solubility, and metabolic pathways. The results indicated that the compound exhibits favorable pharmacokinetic profiles, making it a promising candidate for further drug development.

In addition to its pharmacokinetic properties, recent research has also focused on the mechanistic aspects of 2,2-dimethyl-N-(pyridin-4-yl)propanamide. A study published in the Journal of Medicinal Chemistry demonstrated its ability to modulate specific signaling pathways involved in inflammation. The compound was shown to inhibit the activity of key enzymes such as cyclooxygenase-2 (COX-2), suggesting potential applications in the treatment of chronic inflammatory conditions.

Another area of interest is the compound's role in neurological research. Preliminary findings from a collaborative study between academic and industrial researchers revealed that 2,2-dimethyl-N-(pyridin-4-yl)propanamide can cross the blood-brain barrier (BBB) and interact with neurotransmitter receptors. This discovery opens new avenues for the development of therapeutics targeting neurodegenerative diseases such as Alzheimer's and Parkinson's.

Despite these promising findings, challenges remain in the optimization of 2,2-dimethyl-N-(pyridin-4-yl)propanamide for clinical use. Recent studies have highlighted the need for further structural modifications to enhance its selectivity and reduce potential off-target effects. Computational modeling and structure-activity relationship (SAR) studies are currently underway to address these issues.

In conclusion, the latest research on 2,2-dimethyl-N-(pyridin-4-yl)propanamide (CAS: 70298-89-4) underscores its potential as a versatile scaffold in drug discovery. Its favorable pharmacokinetic properties, combined with its ability to modulate critical biological pathways, make it a valuable candidate for further investigation. Future studies should focus on optimizing its structure and evaluating its efficacy in preclinical models to pave the way for clinical trials.

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