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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoyl derivatives
• Solvents and Organic Chemicals Organic Compounds Aldehyde/Ketone

2-(Methylthio)benzaldehyde (CAS No. 7022-45-9): A Comprehensive Overview

2-(Methylthio)benzaldehyde (CAS No. 7022-45-9) is a versatile organic compound that has garnered significant attention in recent years due to its unique chemical properties and potential applications in various fields, including pharmaceuticals, materials science, and organic synthesis. This compound, also known as o-methylthiobenzaldehyde, is characterized by its aromatic ring structure with a methylthio substituent and an aldehyde functional group. The combination of these features imparts distinct reactivity and functionality, making it a valuable building block in synthetic chemistry.

The molecular formula of 2-(Methylthio)benzaldehyde is C₈H₈S, and its molecular weight is 144.21 g/mol. The compound is a colorless to pale yellow liquid with a characteristic odor. It is soluble in most organic solvents but has limited solubility in water. These physical properties make it suitable for a wide range of applications, from laboratory-scale synthesis to industrial processes.

In the realm of pharmaceutical research, 2-(Methylthio)benzaldehyde has been explored for its potential therapeutic applications. Recent studies have shown that derivatives of this compound exhibit promising biological activities, including anti-inflammatory, antimicrobial, and anticancer properties. For instance, a study published in the Journal of Medicinal Chemistry reported that certain derivatives of 2-(Methylthio)benzaldehyde demonstrated significant inhibition of tumor growth in vitro and in vivo models. This finding opens up new avenues for the development of novel drugs targeting various cancers.

Beyond its pharmaceutical applications, 2-(Methylthio)benzaldehyde has found utility in the synthesis of advanced materials. Its ability to undergo selective functionalization reactions makes it an attractive starting material for the preparation of functional polymers and coatings. Research in this area has focused on developing materials with enhanced mechanical properties, thermal stability, and chemical resistance. For example, a study published in the Journal of Polymer Science described the synthesis of a novel polymer using 2-(Methylthio)benzaldehyde as a key monomer, resulting in a material with superior performance characteristics.

In the field of organic synthesis, 2-(Methylthio)benzaldehyde serves as a versatile intermediate for the preparation of complex molecules. Its reactivity with various nucleophiles and electrophiles allows for the construction of intricate molecular architectures. Recent advancements in catalytic methods have further expanded its synthetic utility. A notable example is the development of palladium-catalyzed cross-coupling reactions involving 2-(Methylthio)benzaldehyde, which have enabled the efficient synthesis of biologically active compounds with high stereocontrol.

The environmental impact of chemicals is an increasingly important consideration in their use and development. Studies on the environmental fate and toxicity of 2-(Methylthio)benzaldehyde have shown that it degrades readily under natural conditions and exhibits low toxicity to aquatic organisms. This favorable environmental profile makes it a preferred choice for green chemistry initiatives aimed at reducing the ecological footprint of chemical processes.

In conclusion, 2-(Methylthio)benzaldehyde (CAS No. 7022-45-9) is a multifaceted compound with a wide array of applications across different scientific disciplines. Its unique chemical structure and reactivity make it an invaluable tool for researchers and industrial chemists alike. As ongoing research continues to uncover new properties and applications, the significance of this compound is likely to grow even further.

• 918882-53-8(2,6-Bis(methylthio)benzaldehyde)
• 549494-75-9(Benzaldehyde, 2,2'-thiobis-)
• 71750-42-0(Benzaldehyde,(methylthio)- (9CI))
• 88339-47-3(Benzaldehyde, 2,3,4,5-tetramethyl-6-(methylthio)-)
• 62351-50-2(Benzaldehyde, 2-[(4-methylphenyl)thio]-)
• 106184-09-2(Benzaldehyde, 2,6-bis(phenylthio)-)
• 13616-73-4(Benzaldehyde, 5-methyl-2-(methylthio)-)
• 333743-61-6(Benzaldehyde, 3-methyl-4-(methylthio)-)
• 36943-39-2(2-(Phenylthio)benzaldehyde)
• 53606-33-0(Benzaldehyde, 2-(ethylthio)-)