Cas no 70110-25-7 ((2R)-2-chloropropanoyl chloride)
(2R)-2-Chloropropanoyl chloride is a chiral acyl chloride derivative characterized by its high reactivity as an electrophilic reagent. Its stereospecific (R)-configuration makes it valuable in asymmetric synthesis, particularly for introducing chiral propionyl groups in pharmaceuticals and fine chemicals. The compound’s chlorine substituent at the α-position enhances its utility in nucleophilic substitution reactions, enabling efficient derivatization. It is commonly employed in peptide coupling, esterification, and amidation reactions due to its ability to form stable intermediates. Handling requires strict anhydrous conditions to prevent hydrolysis. The enantiomeric purity and consistent reactivity of (2R)-2-chloropropanoyl chloride make it a preferred choice for stereocontrolled synthetic applications in research and industrial settings.
70110-25-7 structure
Product Name:(2R)-2-chloropropanoyl chloride
CAS No:70110-25-7
MF:C3H4Cl2O
MW:126.969259262085
MDL:MFCD20621425
CID:547694
PubChem ID:7006443
Update Time:2025-06-07
(2R)-2-chloropropanoyl chloride Chemical and Physical Properties
Names and Identifiers
-
- Propanoyl chloride, 2-chloro-, (2R)-
- R-(-)-2-Chloropropionyl Chloride
- (R)-2-Chloropropionyl chloride
- (2R)-2-chloropropanoyl chloride
- (2R)-2-Chloropropionyl Chloride
- DTXSID70426495
- SCHEMBL1066789
- (2R)-2-CHLOROPROPANOYLCHLORIDE
- EN300-338473
- JEQDSBVHLKBEIZ-UWTATZPHSA-N
- 70110-25-7
-
- MDL： MFCD20621425
- Inchi： 1S/C3H4Cl2O/c1-2(4)3(5)6/h2H,1H3/t2-/m1/s1
- InChI Key： JEQDSBVHLKBEIZ-UWTATZPHSA-N
- SMILES： Cl[C@@H](C(=O)Cl)C
Computed Properties
- Exact Mass: 174.05800
- Monoisotopic Mass: 125.9639201g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 6
- Rotatable Bond Count: 1
- Complexity: 61.8
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.8
- Topological Polar Surface Area: 17.1?2
Experimental Properties
- Density: 1.291±0.06 g/cm3 (20 oC 760 Torr),
- Boiling Point: 110.1±13.0 oC (760 Torr),
- Flash Point: 41.8±20.2 oC,
- Solubility: Slightly soluble (24 g/l) (25 o C),
- PSA: 9.23000
- LogP: 3.75820
(2R)-2-chloropropanoyl chloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-338473-0.1g |
(2R)-2-chloropropanoyl chloride |
70110-25-7 | 95% | 0.1g |
$23.0 | 2023-09-03 | |
| Enamine | EN300-338473-0.25g |
(2R)-2-chloropropanoyl chloride |
70110-25-7 | 95% | 0.25g |
$24.0 | 2023-09-03 | |
| Enamine | EN300-338473-0.5g |
(2R)-2-chloropropanoyl chloride |
70110-25-7 | 95% | 0.5g |
$25.0 | 2023-09-03 | |
| Enamine | EN300-338473-1.0g |
(2R)-2-chloropropanoyl chloride |
70110-25-7 | 95% | 1g |
$28.0 | 2023-06-06 | |
| Enamine | EN300-338473-2.5g |
(2R)-2-chloropropanoyl chloride |
70110-25-7 | 95% | 2.5g |
$55.0 | 2023-09-03 | |
| Enamine | EN300-338473-5.0g |
(2R)-2-chloropropanoyl chloride |
70110-25-7 | 95% | 5g |
$108.0 | 2023-06-06 | |
| Enamine | EN300-338473-10.0g |
(2R)-2-chloropropanoyl chloride |
70110-25-7 | 95% | 10g |
$200.0 | 2023-06-06 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBT0146-5G |
(2R)-2-chloropropanoyl chloride |
70110-25-7 | 95% | 5g |
￥ 363.00 | 2023-03-17 | |
| NAN JING YAO SHI KE JI GU FEN Co., Ltd. | PBT0146-10G |
(2R)-2-chloropropanoyl chloride |
70110-25-7 | 95% | 10g |
￥ 567.00 | 2023-03-17 | |
| Enamine | EN300-338473-0.05g |
(2R)-2-chloropropanoyl chloride |
70110-25-7 | 95% | 0.05g |
$21.0 | 2023-09-03 |
(2R)-2-chloropropanoyl chloride Suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
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(CAS:70110-25-7)(2R)-2-氯丙酰氯
Order Number:LE26812243
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:58
Price ($):discuss personally
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(2R)-2-chloropropanoyl chloride Related Literature
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Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
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Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
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Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361
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Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
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Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
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Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:70110-25-7)(2R)-2-氯丙酰氯
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry