Cas no 700871-88-1 (4,7-Dibromoquinoline)

4,7-Dibromoquinoline is a brominated quinoline derivative widely used as a versatile intermediate in organic synthesis and pharmaceutical research. Its key advantages include high reactivity due to the presence of bromine substituents at the 4 and 7 positions, enabling efficient cross-coupling reactions such as Suzuki or Buchwald-Hartwig amination. The compound exhibits excellent stability under standard conditions, facilitating handling and storage. Its well-defined structure makes it a valuable building block for constructing complex heterocyclic frameworks, particularly in the development of bioactive molecules and materials science applications. The product is typically supplied with high purity, ensuring consistent performance in synthetic workflows.
4,7-Dibromoquinoline structure
4,7-Dibromoquinoline structure
Product Name:4,7-Dibromoquinoline
CAS No:700871-88-1
MF:C9H5Br2N
MW:286.950700521469
MDL:MFCD08063188
CID:557234
PubChem ID:18931869
Update Time:2025-06-13

4,7-Dibromoquinoline Chemical and Physical Properties

Names and Identifiers

    • 4,7-Dibromoquinoline
    • 4-BROMO-7-BROMOQUINOLINE
    • Quinoline, 4,7-dibromo-
    • Quinoline,4,7-dibromo
    • AK111218
    • 0856AC
    • FCH1386350
    • OR307502
    • AX8034677
    • AB0080080
    • T6619
    • SB71551
    • DS-5141
    • MFCD08063188
    • A900626
    • DTXSID10596606
    • 4 pound not7-Dibromoquinoline
    • SCHEMBL4470963
    • A866683
    • AKOS016009555
    • FT-0769574
    • 700871-88-1
    • DB-074253
    • MDL: MFCD08063188
    • Inchi: 1S/C9H5Br2N/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H
    • InChI Key: FARNFRFWNKSWAN-UHFFFAOYSA-N
    • SMILES: BrC1C=CN=C2C=C(C=CC2=1)Br

Computed Properties

  • Exact Mass: 284.87900
  • Monoisotopic Mass: 284.87887g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 0
  • Complexity: 163
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.7
  • Topological Polar Surface Area: 12.9

Experimental Properties

  • Density: 1.923
  • Boiling Point: 352.7°C at 760 mmHg
  • Flash Point: 167.1°C
  • Refractive Index: 1.698
  • PSA: 12.89000
  • LogP: 3.75980

4,7-Dibromoquinoline Customs Data

  • HS CODE:2933499090
  • Customs Data:

    China Customs Code:

    2933499090

    Overview:

    2933499090. Other compounds containing quinoline or isoquinoline ring system [but not further fused]. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4,7-Dibromoquinoline Pricemore >>

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Additional information on 4,7-Dibromoquinoline

Comprehensive Overview of 4,7-Dibromoquinoline (CAS No. 700871-88-1): Properties, Applications, and Industry Insights

4,7-Dibromoquinoline (CAS No. 700871-88-1) is a halogenated quinoline derivative that has garnered significant attention in pharmaceutical and materials science research. This compound, characterized by two bromine atoms at the 4 and 7 positions of the quinoline ring, serves as a versatile intermediate in organic synthesis. Its molecular formula, C9H5Br2N, and unique structural features make it valuable for constructing complex molecules, particularly in the development of fluorescent probes, pharmaceutical intermediates, and organic electronic materials.

The growing demand for 4,7-Dibromoquinoline is closely tied to its role in cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig couplings, which are pivotal in modern drug discovery. Researchers frequently search for "4,7-Dibromoquinoline synthesis" or "CAS 700871-88-1 applications" to explore its utility in creating heterocyclic compounds with potential biological activity. Recent studies highlight its use in designing anticancer agents and antimicrobial scaffolds, aligning with the global focus on novel therapeutics.

From a materials science perspective, 4,7-Dibromoquinoline contributes to advancements in organic light-emitting diodes (OLEDs) and photovoltaic cells. Its bromine substituents facilitate precise molecular engineering, addressing the industry's need for high-efficiency emitters. Queries like "quinoline derivatives for OLEDs" or "700871-88-1 solubility" reflect user interest in optimizing its performance in thin-film technologies.

Analytical data for CAS No. 700871-88-1 reveals a melting point range of 150–152°C and stability under inert conditions, making it suitable for high-temperature applications. Laboratories often inquire about "4,7-Dibromoquinoline purification methods" or "NMR spectra interpretation" to ensure reproducibility in synthetic protocols. The compound’s chromatographic behavior and spectroscopic fingerprints are well-documented, aiding quality control in commercial production.

Environmental and regulatory considerations for 4,7-Dibromoquinoline emphasize green chemistry principles. Innovations in catalyst-free reactions and solvent recovery systems address sustainability concerns, resonating with searches for "eco-friendly quinoline synthesis." Its low acute toxicity profile (as per available data) supports its adoption in industrial-scale processes.

Market trends indicate rising procurement of 700871-88-1 by contract research organizations (CROs) and academic institutions, driven by its cost-effectiveness compared to analogous iodinated quinolines. FAQs such as "4,7-Dibromoquinoline vs. 2,4-dibromoquinoline reactivity" underscore the need for comparative analyses in selective functionalization strategies.

In summary, 4,7-Dibromoquinoline (CAS No. 700871-88-1) bridges multiple scientific disciplines, offering solutions for drug development, advanced materials, and sustainable chemistry. Its well-defined properties and adaptability to diverse reaction conditions position it as a cornerstone in contemporary organic synthesis.

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