• 1. Fe3O4 nanosphere@microporous organic networks: enhanced anode performances in lithium ion batteries through carbonization?
  Byungho Lim,Jaewon Jin,Jin Yoo,Seung Yong Han,Kyeongyeol Kim,Sungah Kang,Nojin Park,Sang Moon Lee,Hae Jin Kim,Seung Uk Son Chem. Commun., 2014,50, 7723-7726
• 2. Evolution of shape, size, and areal density of a single plane of Si nanocrystals embedded in SiO2 matrix studied by atom probe tomography
  Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622
• 3. Fast-pulsing NMR techniques for the detection of weak interactions: successful natural abundance probe of hydrogen bonds in peptides?
  Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
• 4. Fe3O4/PEG-SO3H as a heterogeneous and magnetically-recyclable nanocatalyst for the oxidation of sulfides to sulfones or sulfoxides
  Saeideh Mirfakhraei,Malak Hekmati,Fereshteh Hosseini Eshbala,Hojat Veisi New J. Chem., 2018,42, 1757-1761
• 5. Excimer and exciplex formation in a pair of bright phosphorescent isomers constructed from Cu3(pyrazolate)3 and Cu3I3 coordination luminophores?
  Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Halopyridines Polyhalopyridines

2,3-Dichloro-5-(trichloromethyl)pyridine: A Comprehensive Overview

2,3-Dichloro-5-(trichloromethyl)pyridine, identified by the CAS number 69045-83-6, is a chemically synthesized compound with significant applications in various industrial and scientific domains. This compound belongs to the broader category of chlorinated pyridines, which have been extensively studied for their unique chemical properties and versatile functionalities. The structure of this compound comprises a pyridine ring with two chlorine atoms at positions 2 and 3, and a trichloromethyl group attached at position 5. This specific substitution pattern imparts distinct electronic and steric properties to the molecule, making it highly valuable in different chemical processes.

The synthesis of 2,3-Dichloro-5-(trichloromethyl)pyridine typically involves multi-step reactions that include chlorination and substitution processes. Recent advancements in synthetic chemistry have enabled more efficient and environmentally friendly methods for producing this compound. For instance, researchers have explored the use of microwave-assisted synthesis to accelerate reaction rates while minimizing by-products. Such innovations not only enhance the scalability of production but also align with the growing demand for sustainable chemical manufacturing practices.

One of the most notable applications of 2,3-Dichloro-5-(trichloromethyl)pyridine is in the field of agrochemicals. This compound serves as an intermediate in the synthesis of various pesticides and herbicides. Its ability to inhibit specific enzymes in target organisms makes it a critical component in developing effective crop protection agents. Recent studies have highlighted its role in enhancing the selectivity and efficacy of agricultural chemicals, thereby reducing their environmental impact.

In addition to its agricultural applications, 2,3-Dichloro-5-(trichloromethyl)pyridine has found utility in materials science. It is employed as a precursor in the synthesis of advanced polymers and materials with tailored properties. For example, researchers have utilized this compound to develop high-performance polymers for use in electronics and optoelectronic devices. The trichloromethyl group contributes significantly to the thermal stability and mechanical strength of these materials.

The environmental impact and safety profile of CAS No 69045-83-6 have also been subjects of recent research. Studies indicate that while this compound exhibits moderate toxicity under certain conditions, its environmental persistence is relatively low due to its susceptibility to photodegradation and microbial degradation. Regulatory bodies have established guidelines for handling and disposing of this compound to minimize risks to human health and ecosystems.

From a structural perspective, the pyridine ring in 2,3-Dichloro-5-(trichloromethyl)pyridine provides a rigid framework that facilitates various chemical transformations. The presence of multiple chlorine atoms enhances its reactivity towards nucleophilic substitutions and electrophilic additions. This makes it an ideal substrate for synthesizing more complex molecules with diverse functionalities.

The demand for 2,3-Dichloro-5-(trichloromethyl)pyridine continues to grow as new applications emerge across different industries. Its role as an intermediate in pharmaceutical synthesis has gained traction, particularly in the development of antiviral agents. Researchers are exploring its potential as a building block for creating bioactive compounds with specific therapeutic properties.

In conclusion, CAS No 69045-83-6, or 2,3-Dichloro-5-(trichloromethyl)pyridine, stands out as a versatile compound with wide-ranging applications in agriculture, materials science, and pharmaceuticals. Ongoing research continues to uncover new avenues for its utilization while addressing concerns related to its environmental impact and safety. As industries strive for innovation and sustainability, this compound remains a key player in advancing chemical technologies.

• 59782-90-0(2,3-Dichloro-5-methylpyridine)
• 52465-59-5(2,3,6-Trichloro-5-(chloromethyl)pyridine)
• 113982-12-0(2,3,4,6-tetrachloro-5-(trichloromethyl)pyridine)
• 58584-80-8(2,3,6-trichloro-5-(trichloromethyl)pyridine)
• 95234-75-6(Pyridine,2,4-dichloro-5-(trichloromethyl)-)
• 71701-94-5(Pyridine, 2,5-dichloro-3-(trichloromethyl)-)
• 72637-18-4(2-Chloro-5-(dichloromethyl)pyridine)
• 69045-78-9(2-Chloro-5-(trichloromethyl)pyridine)
• 54127-31-0(2,3-Dichloro-5-(chloromethyl)pyridine)
• 85148-27-2(3-Chloro-5-(trichloromethyl)pyridine)