Cas no 69-81-8 (Carbazochrome)

Carbazochrome is a hemostatic agent derived from adrenochrome, primarily used to control capillary bleeding and reduce vascular permeability. Its mechanism involves stabilizing endothelial cell membranes and promoting platelet aggregation, making it effective in managing hemorrhage in surgical and trauma settings. The compound exhibits low toxicity and is well-tolerated, with rapid onset of action. It is often formulated as an injection or oral tablet for clinical use. Carbazochrome's advantages include its targeted action on microcirculation, minimal side effects, and compatibility with other hemostatic therapies. It is particularly valued in ophthalmology, otolaryngology, and gynecology for its efficacy in controlling localized bleeding.
Carbazochrome structure
Carbazochrome structure
Product Name:Carbazochrome
CAS No:69-81-8
MF:C10H12N4O3
MW:236.227281570435
MDL:MFCD00867500
CID:33902
PubChem ID:87561858
Update Time:2025-10-12

Carbazochrome Chemical and Physical Properties

Names and Identifiers

    • 2-(3-Hydroxy-1-methyl-6-oxo-2,3-dihydro-1H-indol-5(6H)-ylidene)hydrazinecarboxamide
    • adrenochrome monosemicarbazone
    • Carbazochrome
    • Adrenochrome Semicarbazone
    • 3-HYDROXY-1-METHYL-5,6-INDOLINEDIONE SEMICARBAZONE
    • adchnon
    • adedolon
    • Adrenochrom-monosemicarbazon
    • ADRENOXYL
    • adrezon
    • adrokson
    • adroxon
    • cartabes
    • CROMADRENAL
    • CROMOSIL
    • 3-Hydroxy-1-methyl-5,6-indolinedione 5-semicarbazone
    • Carbazochrom
    • Adrenostazin
    • Sangostasin
    • Sangostazin
    • Adrenostan
    • Carbazochromum
    • Carbazocromo
    • Cromoxin
    • Adenocrome monosemicarbazone
    • Adrenoxil
    • Apara
    • Carbazochrome [INN:JAN]
    • Adrenochrome monosemicarbazon
    • Carbazocromo [INN-Spanish]
    • Car
    • Adrenochrome monosemicarbazone; Adrenostazin; Adrenoxyl; Adrezon
    • SCHEMBL11036230
    • 3-Hydroxy-1-methyl-5,6-inodlindionsemicarbazon
    • W-104582
    • DS-4533
    • CARBAZOCHROME [MI]
    • NCGC00164521-01
    • SY057431
    • BCP15360
    • NSC73742
    • D01864
    • NCGC00344541-01
    • ZINC03871875
    • {[(5E)-3-Hydroxy-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indol-5-ylidene]amino}urea
    • NSC-73742
    • L 502
    • CHEMBL2051960
    • A0176
    • 69-81-8
    • (3,6-dihydroxy-1-methyl-2,3-dihydroindol-5-yl)iminourea
    • 5, 3-hydroxy-1-methyl-, 5-semicarbazone
    • LS-83455
    • 5,6-INDOLINEDIONE, 3-HYDROXY-1-METHYL-, 5-SEMICARBAZONE
    • s5084
    • CS-0013486
    • CAS-69-81-8
    • CHEBI:31349
    • 3-Hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione 5-semicarbazone #
    • (E)-2-(3-hydroxy-1-methyl-6-oxo-2,3-dihydro-1H-indol-5(6H)-ylidene)hydrazinecarboxamide
    • 81F061RQS4
    • [(Z)-(3-hydroxy-1-methyl-6-oxo-2,3-dihydroindol-5-ylidene)amino]urea
    • Hydrazinecarboxamide, 2-(1,2,3,6-tetrahydro-3-hydroxy-1-methyl-6-oxo-5H-indol-5-ylidene)-
    • Adrenochromsemicarbazon
    • AC-31089
    • CS-O-01053
    • CARBAZOCHROME [JAN]
    • Q1104521
    • XSXCZNVKFKNLPR-SDQBBNPISA-N
    • CCG-266833
    • DTXSID3048310
    • 3-Hydroxy-1-methyl-5-semicarbazono-6(5H)-indolinon
    • ADRENOCHROME MONOSEMICARBAZONE [MI]
    • NSC 73742
    • 2-(1,2,3,6-Tetrahydro-3-hydroxy-1-methyl-6-oxo-5H-indol-5-ylidene)hydrazinecarboxamide
    • Carbazochromum [INN-Latin]
    • H11624
    • CHEMBL4789892
    • DTXCID00809636
    • HY-B1587
    • DB09012
    • SB67333
    • AKOS024319075
    • EINECS 200-717-0
    • 2,3-Dihydro-3-hydroxy-1-methyl-1H-indole-5,6-dione-5-semicarbazone
    • AKOS015896532
    • Carbazochrome,(S)
    • CARBAZOCHROME [WHO-DD]
    • 5,6-dihydro-3-hydroxy-1-methyl-5,6-indolindion-5-semicarbazon
    • CARBAZOCHROME [INN]
    • MFCD00130253
    • Carbazochrome (JAN/INN)
    • AMY39497
    • Tox21_113160
    • Hydrazinecarboxamide,2,3,6-tetrahydro-3-hydroxy-1-methyl-6-oxo-5H-indol-5-ylidene)-
    • CARBAZOCHROME [MART.]
    • AKOS030242682
    • UNII-81F061RQS4
    • SCHEMBL506178
    • NS00077991
    • 6-Indolinone, 3-hydroxy-1-methyl-5-semicarbazono-
    • SSCSSDNTQJGTJT-UHFFFAOYSA-N
    • DA-62054
    • XSXCZNVKFKNLPR-UHFFFAOYSA-N
    • MDL： MFCD00867500
    • Inchi： 1S/C10H12N4O3/c1-14-4-9(16)5-2-6(12-13-10(11)17)8(15)3-7(5)14/h2-3,9,15-16H,4H2,1H3,(H2,11,17)/b13-12+
    • InChI Key： SSCSSDNTQJGTJT-OUKQBFOZSA-N
    • SMILES： OC1C2C=C(C(=CC=2N(C)C1)O)/N=N/C(N)=O

Computed Properties

  • Exact Mass: 236.09100
  • Monoisotopic Mass: 236.091
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 1
  • Complexity: 336
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 112
  • Surface Charge: 0
  • Tautomer Count: 7
  • XLogP3: -1.6

Experimental Properties

  • Color/Form: Orange crystal or crystalline powder.
  • Density: 1.63 g/cm3
  • Melting Point: 203° (dec)
  • Refractive Index: 1.732
  • PSA: 108.02000
  • LogP: -0.26090
  • Solubility: Slightly soluble in water and ethanol, insoluble in ether and chloroform. Its sodium salicylate salt ([1305-01-9]) is an orange powder with a melting point of 196- 197.5 ℃ (decomposition), a solubility of 0.61mg/ml in water at 25 ℃, insoluble in ether and chloroform, and a pH value of 10% aqueous solution of 6.7-7.3.
  • Merck: 172

Carbazochrome Security Information

Carbazochrome Customs Data

  • HS CODE：2933990090
  • Customs Data：

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Carbazochrome Suppliers

Amadis Chemical Company Limited
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(CAS:69-81-8)Carbazochrome
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Quantity:100g
Purity:99%
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Price ($):164.0
Suzhou Senfeida Chemical Co., Ltd
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(CAS:69-81-8)Carbazochrome
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(CAS:69-81-8)Carbazochrome, ≥ 99.0%
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(CAS:69-81-8)Carbazochrome
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Price ($):negotiated

Carbazochrome Related Literature

Additional information on Carbazochrome

Carbazochrome: A Comprehensive Overview

Carbazochrome (CAS No. 69-81-8) is a compound of significant interest in the fields of organic chemistry and materials science. This compound, also known as carbazole-based chromophore, has garnered attention due to its unique electronic properties and potential applications in optoelectronic devices. Recent advancements in the synthesis and characterization of Carbazochrome have further highlighted its versatility and promise in modern technological applications.

The molecular structure of Carbazochrome is characterized by a carbazole moiety, which consists of a benzene ring fused with an indole ring. This structure imparts the compound with excellent charge transport properties, making it an ideal candidate for use in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs). Researchers have recently explored the integration of Carbazochrome into these devices, demonstrating enhanced efficiency and stability compared to traditional materials.

One of the most notable recent studies on Carbazochrome involves its application in flexible electronics. Scientists have successfully synthesized a novel derivative of Carbazochrome that exhibits superior mechanical flexibility and electrical conductivity. This breakthrough has opened new avenues for the development of wearable devices and foldable displays, which are increasingly demanded by the modern tech industry.

In addition to its electronic applications, Carbazochrome has also been investigated for its potential in biomedical imaging. By functionalizing Carbazochrome with targeting ligands, researchers have developed a new class of fluorescent probes that can selectively bind to specific biomolecules. These probes have shown remarkable sensitivity and specificity in detecting cancer biomarkers, offering a promising tool for early diagnosis and treatment monitoring.

The synthesis of Carbazochrome has undergone significant improvements in recent years. Traditional methods often involved multi-step reactions with low yields, limiting its widespread use. However, recent advancements in catalytic techniques have enabled the development of more efficient and scalable synthesis routes for Carbazochrome. These methods not only improve yield but also reduce production costs, making the compound more accessible for industrial applications.

Another area where Carbazochrome has made an impact is in energy storage systems. Researchers have explored the use of Carbazochrome as an electrolyte additive in lithium-ion batteries, demonstrating improved cycle life and charge-discharge efficiency. This application underscores the compound's potential beyond traditional optoelectronic uses, highlighting its role in advancing sustainable energy technologies.

Despite its numerous advantages, the environmental impact of Carbazochrome remains a critical consideration. Recent studies have focused on understanding the degradation pathways of Carbazochrome under various environmental conditions. These investigations aim to develop strategies for minimizing its ecological footprint while maximizing its benefits across diverse applications.

In conclusion, Carbazochrome (CAS No. 69-81-8) stands as a testament to the ongoing innovation in materials science and organic chemistry. Its unique properties, coupled with recent research advancements, position it as a key player in next-generation technologies ranging from flexible electronics to biomedical imaging and energy storage systems. As research continues to unfold, the potential applications of Carbazochrome are expected to expand further, driving new opportunities for scientific discovery and industrial innovation.

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