Cas no 687636-95-9 (5-(methoxymethyl)-1,3-thiazole-2-carbaldehyde)

5-(Methoxymethyl)-1,3-thiazole-2-carbaldehyde is a versatile heterocyclic aldehyde with a thiazole core, functionalized with a methoxymethyl group at the 5-position. This compound is particularly valuable in organic synthesis and pharmaceutical research due to its reactive aldehyde moiety, which facilitates further derivatization, such as condensation or nucleophilic addition reactions. The methoxymethyl substituent enhances solubility and stability, making it suitable for use in diverse reaction conditions. Its structural features are advantageous in the development of bioactive molecules, agrochemicals, and functional materials. The compound’s well-defined reactivity profile and synthetic utility underscore its importance as a building block in medicinal and industrial chemistry applications.
5-(methoxymethyl)-1,3-thiazole-2-carbaldehyde structure
687636-95-9 structure
Product Name:5-(methoxymethyl)-1,3-thiazole-2-carbaldehyde
CAS No:687636-95-9
MF:C6H7NO2S
MW:157.190280199051
CID:1019997
PubChem ID:45083916
Update Time:2025-10-28

5-(methoxymethyl)-1,3-thiazole-2-carbaldehyde Chemical and Physical Properties

Names and Identifiers

    • 5-(methoxymethyl)-2-Thiazolecarboxaldehyde
    • 2-Thiazolecarboxaldehyde, 5-(methoxymethyl)- (9CI)
    • 5-(methoxymethyl)-1,3-thiazole-2-carboxaldehyde
    • EN300-125302
    • AKOS026729763
    • 5-(methoxymethyl)-1,3-thiazole-2-carbaldehyde
    • 5-(methoxymethyl)thiazole-2-carbaldehyde
    • Z1216838520
    • SCHEMBL4685254
    • 687636-95-9
    • DB-332716
    • Inchi: 1S/C6H7NO2S/c1-9-4-5-2-7-6(3-8)10-5/h2-3H,4H2,1H3
    • InChI Key: MROOUGKBDMDJTA-UHFFFAOYSA-N
    • SMILES: S1C(C=O)=NC=C1COC

Computed Properties

  • Exact Mass: 157.01974964g/mol
  • Monoisotopic Mass: 157.01974964g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 3
  • Complexity: 120
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.4
  • Topological Polar Surface Area: 67.4?2

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