Cas no 66937-99-3 (Morpholine-3-carboxylic acid hydrochloride)
Morpholine-3-carboxylic acid hydrochloride Chemical and Physical Properties
Names and Identifiers
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- Morpholine-3-carboxylic acid hydrochloride
- 3-MORPHOLINECARBOXYLIC ACID HYDROCHLORIDE
- 3-Morpholinecarboxylic acid, hydrochloride
- Morpholine-3-carboxylic acid HCl
- (S)-3-Morpholinecarboxylic acid hydrochloride
- AK109013
- AK162039
- CWSLARZELUGARZ-UHFFFAOYSA-N
- SB21043
- TRA0074512
- RP23038
- (RS)-Morpholine-3-carboxylic acid HCl
- SY030470
- SY
- SB21044
- MFCD06809588
- EN300-90597
- Z1255387606
- SY116240
- AM20100777
- A867360
- 3-Morpholine carboxylic acid hydrochloride
- SB31242
- FT-0750283
- MFCD08752601
- MORPHOLINE-3-CARBOXYLICACIDHYDROCHLORIDE
- DTXSID50672357
- Morpholine-3-carboxylic acid--hydrogen chloride (1/1)
- J-522720
- SCHEMBL2075067
- morpholine-3-carboxylic acid;hydrochloride
- AC-7119
- 3-Morpholinecarboxylic acid HCl
- SY004044
- DS-14306
- AKOS005257966
- CS-0043809
- 66937-99-3
- DB-073817
- (R)-3-Morpholinecarboxylicacidhydrochloride
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- MDL： MFCD08752601
- Inchi： 1S/C5H9NO3.ClH/c7-5(8)4-3-9-2-1-6-4;/h4,6H,1-3H2,(H,7,8);1H
- InChI Key： CWSLARZELUGARZ-UHFFFAOYSA-N
- SMILES： Cl.O1CCNC(C(=O)O)C1
Computed Properties
- Exact Mass: 167.03500
- Monoisotopic Mass: 167.035
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 10
- Rotatable Bond Count: 1
- Complexity: 115
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 58.6
Experimental Properties
- Melting Point: 245-250 °C
- PSA: 58.56000
- LogP: 0.19020
Morpholine-3-carboxylic acid hydrochloride Security Information
- Signal Word：Warning
- Hazard Statement： H302;H315;H319;H335
- Warning Statement： P261;P305+P351+P338
- Storage Condition：Room temperature
Morpholine-3-carboxylic acid hydrochloride Customs Data
- HS CODE：2934999090
- Customs Data：
China Customs Code:
2934999090Overview:
2934999090. Other heterocyclic compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to
Summary:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Morpholine-3-carboxylic acid hydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 53R0023S-1g |
Morpholine-3-carboxylic acid hydrochloride |
66937-99-3 | 97% | 1g |
407.06CNY | 2021-05-07 | |
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 53R0023S-5g |
Morpholine-3-carboxylic acid hydrochloride |
66937-99-3 | 97% | 5g |
1679.12CNY | 2021-05-07 | |
| JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd. | 53R0023S-25g |
Morpholine-3-carboxylic acid hydrochloride |
66937-99-3 | 97% | 25g |
5919.34CNY | 2021-05-07 | |
| Fluorochem | 050103-250mg |
Morpholine-3-carboxylic acid hydrochloride |
66937-99-3 | 97% | 250mg |
￡22.00 | 2022-03-01 | |
| Fluorochem | 050103-1g |
Morpholine-3-carboxylic acid hydrochloride |
66937-99-3 | 97% | 1g |
￡42.00 | 2022-03-01 | |
| Fluorochem | 050103-5g |
Morpholine-3-carboxylic acid hydrochloride |
66937-99-3 | 97% | 5g |
￡166.00 | 2022-03-01 | |
| Fluorochem | 050103-25g |
Morpholine-3-carboxylic acid hydrochloride |
66937-99-3 | 97% | 25g |
￡768.00 | 2022-03-01 | |
| AstaTech | 63498-1/G |
MORPHOLINE-3-CARBOXYLIC ACID HCL |
66937-99-3 | 97% | 1g |
$39 | 2023-09-16 | |
| AstaTech | 63498-5/G |
MORPHOLINE-3-CARBOXYLIC ACID HCL |
66937-99-3 | 97% | 5g |
$93 | 2023-09-16 | |
| AstaTech | 63498-25/G |
MORPHOLINE-3-CARBOXYLIC ACID HCL |
66937-99-3 | 97% | 25/G |
$682 | 2022-06-01 |
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Morpholine-3-carboxylic acid hydrochloride Related Literature
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M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
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Craig A. Kelly,David R. Rosseinsky Phys. Chem. Chem. Phys., 2001,3, 2086-2090
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Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
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Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
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Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
Additional information on Morpholine-3-carboxylic acid hydrochloride
Recent Advances in the Research of Morpholine-3-carboxylic acid hydrochloride (CAS: 66937-99-3)
Morpholine-3-carboxylic acid hydrochloride (CAS: 66937-99-3) is a key intermediate in the synthesis of various pharmaceutical compounds, particularly those targeting central nervous system (CNS) disorders and infectious diseases. Recent studies have highlighted its significance in the development of novel therapeutic agents, owing to its unique chemical properties and biological activity. This research brief aims to summarize the latest findings related to this compound, focusing on its synthesis, applications, and potential therapeutic benefits.
In a 2023 study published in the Journal of Medicinal Chemistry, researchers explored the role of Morpholine-3-carboxylic acid hydrochloride in the synthesis of protease inhibitors. The study demonstrated that this compound serves as a critical building block for inhibitors targeting viral proteases, including those of SARS-CoV-2 and HIV. The researchers employed a multi-step synthetic route to optimize the yield and purity of the final product, achieving a significant improvement over previous methods. These findings underscore the compound's potential in antiviral drug development.
Another recent investigation, featured in Bioorganic & Medicinal Chemistry Letters, focused on the compound's application in CNS drug discovery. The study revealed that derivatives of Morpholine-3-carboxylic acid hydrochloride exhibit high affinity for GABAA receptors, making them promising candidates for the treatment of anxiety and epilepsy. The researchers utilized computational modeling and in vitro assays to identify the most potent derivatives, paving the way for further preclinical studies.
Additionally, a 2024 report in ACS Chemical Biology highlighted the compound's role in antibiotic development. The study found that Morpholine-3-carboxylic acid hydrochloride derivatives exhibit potent activity against multidrug-resistant bacterial strains, including MRSA and Pseudomonas aeruginosa. The researchers attributed this activity to the compound's ability to disrupt bacterial cell wall synthesis, a mechanism distinct from existing antibiotics. These results suggest a potential new avenue for addressing the global antibiotic resistance crisis.
In conclusion, recent research on Morpholine-3-carboxylic acid hydrochloride (CAS: 66937-99-3) has demonstrated its versatility and importance in pharmaceutical development. From antiviral and CNS applications to antibiotic discovery, this compound continues to be a focal point of innovative drug design. Future studies are expected to further explore its therapeutic potential and optimize its synthetic pathways for industrial-scale production.
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