Cas no 6677-19-6 (Prednisone 17, 21-Diacetate)

Prednisone 17,21-Diacetate is a synthetic corticosteroid derivative characterized by the acetylation of hydroxyl groups at the 17 and 21 positions of the prednisone structure. This modification enhances the compound's lipophilicity, improving membrane permeability and bioavailability. The diacetate form offers increased stability and controlled release properties, making it suitable for research applications requiring prolonged glucocorticoid activity. It retains the anti-inflammatory and immunosuppressive effects typical of corticosteroids, with potential utility in pharmacological studies exploring metabolic pathways or receptor interactions. The acetylated groups also facilitate derivatization for further chemical modifications, broadening its applicability in synthetic and analytical chemistry.
Prednisone 17, 21-Diacetate structure
Prednisone 17, 21-Diacetate structure
Product Name:Prednisone 17, 21-Diacetate
CAS No:6677-19-6
MF:C25H30O7
MW:442.501508235931
CID:1062928
PubChem ID:13532419
Update Time:2025-11-01

Prednisone 17, 21-Diacetate Chemical and Physical Properties

Names and Identifiers

    • Prednisone 17, 21-Diacetate
    • Prednisone 17, 21-Di
    • (9ξ,14ξ,17ξ)-3,11,20-Trioxopregna-1,4-diene-17,21-diyl diacetate
    • ADKSQQOMYDIKJT-AHLAAXOLSA-N
    • SCHEMBL12380927
    • [2-[(8S,9S,10R,13S,14S,17R)-17-acetyloxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
    • acetic acid (8S,9S,10R,13S,14S,17R)-17-(2-acetoxy-acetyl)-10,13-dimethyl-3,11-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[alpha]phenanthren-17-yl ester
    • acetic acid (8S,9S,10R,13S,14S,17R)-17-(2-acetoxy-acetyl)-10,13-dimethyl-3,11dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester
    • 6677-19-6
    • 17,21-Bis(acetyloxy)-pregna-1,4-diene-3,11,20-trione; 17,21-Dihydroxy-pregna-1,4-diene-3,11,20-trione Diacetate
    • Inchi： 1S/C25H30O7/c1-14(26)31-13-21(30)25(32-15(2)27)10-8-19-18-6-5-16-11-17(28)7-9-23(16,3)22(18)20(29)12-24(19,25)4/h7,9,11,18-19,22H,5-6,8,10,12-13H2,1-4H3/t18-,19-,22+,23-,24-,25-/m0/s1
    • InChI Key： ADKSQQOMYDIKJT-AHLAAXOLSA-N
    • SMILES： O(C(C)=O)[C@]1(C(COC(C)=O)=O)CC[C@H]2[C@@H]3CCC4=CC(C=C[C@]4(C)[C@H]3C(C[C@@]21C)=O)=O

Computed Properties

  • Exact Mass: 442.19900
  • Monoisotopic Mass: 442.19915329g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 7
  • Heavy Atom Count: 32
  • Rotatable Bond Count: 6
  • Complexity: 975
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 6
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3
  • Topological Polar Surface Area: 104?2

Experimental Properties

  • PSA: 103.81000
  • LogP: 2.90740

Prednisone 17, 21-Diacetate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
P703785-50mg
Prednisone 17, 21-Diacetate
 6677-19-6
50mg
 $ 110.00 2023-09-06
TRC
P703785-100mg
Prednisone 17, 21-Diacetate
 6677-19-6
100mg
 $ 173.00 2023-09-06
TRC
P703785-250mg
Prednisone 17, 21-Diacetate
 6677-19-6
250mg
 $ 397.00 2023-09-06
TRC
P703785-500mg
Prednisone 17, 21-Diacetate
 6677-19-6
500mg
 $764.00 2023-05-17
TRC
P703785-1g
Prednisone 17, 21-Diacetate
 6677-19-6
1g
 $ 1110.00 2022-06-03
TRC
P703785-1000mg
Prednisone 17, 21-Diacetate
 6677-19-6
1g
 $1355.00 2023-05-17
SHENG KE LU SI SHENG WU JI SHU
sc-476976-100 mg
Prednisone 17, 21-Diacetate,
 6677-19-6
100MG
 ￥2,708.00 2023-07-11
SHENG KE LU SI SHENG WU JI SHU
sc-476976-100mg
Prednisone 17, 21-Diacetate,
 6677-19-6
100mg
 ￥2708.00 2023-09-05

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