Cas no 66656-92-6 (Esculentoside H)

Esculentoside H is a triterpenoid saponin derived from the roots of Phytolacca esculenta, a plant traditionally used in herbal medicine. This compound exhibits notable anti-inflammatory and immunomodulatory properties, making it a subject of interest in pharmacological research. Its mechanism of action involves the inhibition of pro-inflammatory cytokines, such as TNF-α and IL-6, which contributes to its potential therapeutic applications in inflammatory diseases. Esculentoside H is characterized by its high purity and stability, ensuring reliable performance in experimental studies. Its well-defined molecular structure allows for precise investigation into structure-activity relationships, supporting advancements in drug development and biomedical research.
Esculentoside H structure
Esculentoside H structure
Product Name:Esculentoside H
CAS No:66656-92-6
MF:C48H76O21
MW:989.104457855225
CID:964360
PubChem ID:73157054
Update Time:2025-11-05

Esculentoside H Chemical and Physical Properties

Names and Identifiers

    • esculentoside H
    • LogP
    • 3-O-(O-beta-D-glucopyranosyl-(1→4)-beta-D-xylopyranosyl)-28-beta-D-glucopyranosylphytolaccagenin
    • 2-O-Methyl 4a-O-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (2S,4aR,6aR,6aS,6bR,8
    • CS-0019511
    • AKOS037515095
    • MS-31843
    • A918275
    • 28-beta-D-Glucopyranosyl 29-methyl (2beta,3beta,4alpha,20beta)-3-[(4-O-beta-D-glucopyranosyl-beta-D-xylopyranosyl)oxy]-2,23-dihydroxyolean-12-ene-28,29-dioate
    • NS00093713
    • DTXSID701101662
    • 66656-92-6
    • HY-N2205
    • EsculentosideH
    • Olean-12-ene-28,29-dioic acid, 3-((4-O-beta-D-glucopyranosyl-beta-D-xylopyranosyl)oxy)-2,23-dihydroxy-, 28-beta-D-glucopyranosyl 29-methyl ester, (2beta,3beta,4alpha,20beta)-
    • 3-O-(beta-D-Glucopyranosyl-(1-4)-beta-D-xylopyranosyl)-28-O-beta-D-glucopyranosylphytolaccagenin
    • FT-0775788
    • 28-I(2)-D-Glucopyranosyl 29-methyl (2I(2),3I(2),4I+/-,20I(2))-3-[(4-O-I(2)-D-glucopyranosyl-I(2)-D-xylopyranosyl)oxy]-2,23-dihydroxyolean-12-ene-28,29-dioate
    • DA-63282
    • Esculentoside H
    • Inchi: 1S/C48H76O21/c1-43(41(61)63-6)11-13-48(42(62)69-40-36(60)33(57)30(54)25(18-50)66-40)14-12-46(4)21(22(48)15-43)7-8-28-44(2)16-23(52)37(45(3,20-51)27(44)9-10-47(28,46)5)68-38-34(58)31(55)26(19-64-38)67-39-35(59)32(56)29(53)24(17-49)65-39/h7,22-40,49-60H,8-20H2,1-6H3/t22-,23-,24+,25+,26+,27+,28+,29+,30+,31-,32-,33-,34+,35+,36+,37-,38-,39-,40-,43-,44-,45-,46+,47+,48-/m0/s1
    • InChI Key: UQCUBQIHIKJPHI-PMUXBYKWSA-N
    • SMILES: O([C@H]1[C@@H]([C@H]([C@@H](CO1)O[C@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)O)O)O)[C@H]1[C@H](C[C@@]2(C)[C@@H](CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@@H](CO)O6)O)O)O)CC[C@@](C(=O)OC)(C)C[C@H]5C4=CC[C@@H]32)[C@]1(C)CO)O

Computed Properties

  • Exact Mass: 988.48791
  • Monoisotopic Mass: 988.48791
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 12
  • Hydrogen Bond Acceptor Count: 21
  • Heavy Atom Count: 69
  • Rotatable Bond Count: 12
  • Complexity: 1920
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 24
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -1
  • Topological Polar Surface Area: 342
  • Molecular Weight: 989.1

Experimental Properties

  • Color/Form: Powder
  • Density: 1.48±0.1 g/cm3 (20 oC 760 Torr),
  • Melting Point: 218-220°C
  • Boiling Point: 1042.8°C at 760 mmHg
  • Flash Point: 295.3°C
  • Refractive Index: 1.634
  • Solubility: Insuluble (6.9E-4 g/L) (25 oC),

Esculentoside H Pricemore >>

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Additional information on Esculentoside H

Exploring Esculentoside H (CAS No. 66656-92-6): A Comprehensive Review of Its Properties and Applications

Esculentoside H (CAS No. 66656-92-6) is a naturally occurring saponin compound derived from plants, particularly from the Phytolaccaceae family. This bioactive molecule has garnered significant attention in recent years due to its potential therapeutic properties, including anti-inflammatory, antioxidant, and immunomodulatory effects. Researchers and healthcare professionals are increasingly interested in Esculentoside H as a promising candidate for nutraceutical and pharmaceutical applications.

The chemical structure of Esculentoside H features a triterpenoid backbone with sugar moieties, which contributes to its unique biological activities. Studies have shown that this compound interacts with cellular pathways involved in inflammation and oxidative stress, making it a subject of interest for conditions such as arthritis, cardiovascular diseases, and metabolic disorders. The growing demand for natural and plant-based remedies has further propelled research into Esculentoside H and its derivatives.

In the context of modern health trends, Esculentoside H aligns with the rising popularity of natural anti-inflammatory agents and plant-derived therapeutics. Consumers are increasingly searching for alternatives to synthetic drugs, and compounds like Esculentoside H offer a viable option. Online searches for "Esculentoside H benefits", "natural saponins for health", and "CAS 66656-92-6 uses" reflect this growing curiosity.

From a pharmacological perspective, Esculentoside H has demonstrated efficacy in preclinical studies. Its ability to modulate immune responses and reduce inflammatory markers suggests potential applications in autoimmune diseases and chronic inflammation. Additionally, its antioxidant properties may contribute to its protective effects against oxidative damage, a key factor in aging and degenerative diseases.

The safety profile of Esculentoside H is another area of interest. Preliminary studies indicate that it is well-tolerated in animal models, but further research is needed to establish its safety and efficacy in humans. This aligns with the broader scientific community's focus on evidence-based natural products and their integration into mainstream medicine.

In the field of nutraceuticals, Esculentoside H is being explored as a functional ingredient in dietary supplements. Its potential to support joint health, immune function, and overall wellness makes it a compelling addition to the growing market of plant-based health solutions. Companies are increasingly incorporating such bioactive compounds into their formulations to meet consumer demand for science-backed natural products.

Looking ahead, the future of Esculentoside H research appears promising. With advancements in extraction techniques and analytical methods, scientists are better equipped to study its mechanisms of action and potential applications. The compound's versatility and natural origin position it as a valuable asset in the ongoing quest for sustainable and effective health solutions.

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