Cas no 6665-86-7 (7-Hydroxyflavone)
7-Hydroxyflavone Chemical and Physical Properties
Names and Identifiers
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- 7-HYDROXYFLAVONE
- TIMTEC-BB SBB005921
- 7-HYDROXY-2-PHENYL-4H-CHROMEN-4-ONE
- 7-HYDROXY-2-PHENYLCHROMONE
- HYDROXYFLAVONE, 7-
- 7-hydroxy-2-phenyl-4-benzopyrone
- HYDROXYFLAVONE, 7-(RG)
- 7-hydroxy-2-phenylchromen-4-one
- 7-Hydroxy-2-phenyl-4H-1-benzopyran-4-one
- NSC 94258
- Flavone, 7-hydroxy-
- 4H-1-Benzopyran-4-one, 7-hydroxy-2-phenyl-
- 4H-1-Benzopyran-4-one, 7-hydroxy-
- 7-Hydroxy-2-phenyl-chromen-4-one
- MLS002695239
- MQGPSCMMNJKMHQ-UHFFFAOYSA-N
- ZE72458E4L
- NSC94258
- 7-Hydro
- EINECS 229-705-3
- Q27105601
- 7-hydroxy flavone
- s5380
- SR-01000359106-3
- BDBM26664
- SY048832
- FT-0621434
- HY-N7108
- NSC-94258
- NCGC00163568-01
- NS00046379
- BRD-K56450366-001-01-1
- H-5100
- ACon1_000093
- CCG-208393
- MEGxp0_001698
- AS-19983
- MFCD00006835
- SBI-0207061.P001
- H0852
- BRD-K56450366-001-03-7
- SR-01000359106-1
- 7-Hydroxy-2-phenyl-4H-chromen-4-one #
- 7-Hydroxyflavone, >=98%
- 7-Hydroxy-flavone, 5a
- A12739
- SR-01000359106
- CS-0081150
- NCGC00163568-02
- CHEBI:2268
- UNII-ZE72458E4L
- BIDD:ER0599
- SCHEMBL312148
- NCGC00168801-01
- CHEMBL276915
- Oprea1_774070
- SMR000112319
- 7-Hydroxyflavone, 11
- AKOS000599907
- 7--HYDROXY-2-PHENYL-4-BENZOPYRONE
- 6665-86-7
- DTXSID3022328
- 7-hydroxy-4-oxo-2-phenyl-4H-1-benzopyran
- 7-hydroxy-2-phenyl-4-oxo-4H-1-benzopyran
- BBL100067
- DB-054948
- STL511043
- 7-Hydroxyflavone
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- MDL： MFCD00006835
- Inchi： 1S/C15H10O3/c16-11-6-7-12-13(17)9-14(18-15(12)8-11)10-4-2-1-3-5-10/h1-9,16H
- InChI Key： MQGPSCMMNJKMHQ-UHFFFAOYSA-N
- SMILES： O1C(=CC(C2C=CC(=CC1=2)O)=O)C1C=CC=CC=1
- BRN： 194089
Computed Properties
- Exact Mass: 238.06300
- Monoisotopic Mass: 238.062994
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 18
- Rotatable Bond Count: 1
- Complexity: 355
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 5
- XLogP3: 3.6
- Topological Polar Surface Area: 46.5
Experimental Properties
- Color/Form: Yellow cryst.
- Density: 1.340±0.06 g/cm3 (20 oC 760 Torr),
- Melting Point: 245-247?°C (lit.)
- Boiling Point: 320.83°C (rough estimate)
- Flash Point: 176.3°C
- Refractive Index: 1.5740 (estimate)
- Solubility: Almost insoluble (0.038 g/l) (25 o C),
- PSA: 50.44000
- LogP: 3.16560
7-Hydroxyflavone Security Information
-
Symbol:
- Prompt：warning
- Signal Word：Warning
- Hazard Statement： H315-H319
- Warning Statement： P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Hazard Category Code： 36/37/38
- Safety Instruction： S26-S37/39
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Hazardous Material Identification：
- Risk Phrases：R36/37/38
7-Hydroxyflavone Customs Data
- HS CODE：2914400090
- Customs Data：
China Customs Code:
2914400090Overview:
2914400090 Other ketone alcohols and ketone aldehydes.Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:5.5%.general tariff:30.0%
Declaration elements:
Product Name, component content, use to, Acetone declared packaging
Summary:
2914400090 other ketone-alcohols and ketone-aldehydes.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:5.5%.General tariff:30.0%
7-Hydroxyflavone Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | H862362-1g |
7-Hydroxyflavone |
6665-86-7 | ≥97%(T) | 1g |
￥596.00 | 2022-01-10 | |
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | H4530-1G |
7-Hydroxyflavone |
6665-86-7 | ≥98% | 1G |
440 | 2021-05-17 | |
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | H0852-5G |
7-Hydroxyflavone |
6665-86-7 | >97.0%(T) | 5g |
￥1060.00 | 2024-04-15 | |
| TRC | H942418-10mg |
7-Hydroxyflavone |
6665-86-7 | 10mg |
$ 50.00 | 2022-06-02 | ||
| TRC | H942418-50mg |
7-Hydroxyflavone |
6665-86-7 | 50mg |
$ 65.00 | 2022-06-02 | ||
| TRC | H942418-100mg |
7-Hydroxyflavone |
6665-86-7 | 100mg |
$ 80.00 | 2022-06-02 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | H42121-1g |
7-Hydroxy-2-phenyl-4H-chromen-4-one |
6665-86-7 | 97% | 1g |
￥328.0 | 2023-09-07 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | H42120-20mg |
7-Hydroxy-2-phenyl-4H-chromen-4-one |
6665-86-7 | ,HPLC≥98% | 20mg |
￥378.0 | 2023-09-07 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | T7472-5 mg |
7-Hydroxyflavone |
6665-86-7 | 98.00% | 5mg |
￥267.00 | 2022-04-26 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | T7472-10 mg |
7-Hydroxyflavone |
6665-86-7 | 98.00% | 10mg |
￥387.00 | 2022-04-26 |
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7-Hydroxyflavone Related Literature
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I. E. Serdiuk,A. D. Roshal RSC Adv. 2015 5 102191
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Wen Jiang,Ming Hu RSC Adv. 2012 2 7948
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3. Influence of glucose on the human serum albumin–flavone interaction and their antioxidant activityShaolong Du,Yixi Xie,Xiaoqing Chen Mol. BioSyst. 2013 9 55
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Alok Kumar Verma,Ram Pratap Nat. Prod. Rep. 2010 27 1571
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Alok Kumar Verma,Ram Pratap Nat. Prod. Rep. 2010 27 1571
Additional information on 7-Hydroxyflavone
7-Hydroxyflavone (CAS No. 6665-86-7): A Comprehensive Overview
7-Hydroxyflavone, with the chemical abstracts service (CAS) number 6665-86-7, is a naturally occurring flavonoid that has garnered significant attention in the fields of chemistry, biology, and pharmacology. This compound is characterized by its unique chemical structure, which includes a hydroxyl group at the 7-position of the flavone backbone. The molecular formula of 7-Hydroxyflavone is C15H10O4, and its molecular weight is 258.23 g/mol.
The biological activities of 7-Hydroxyflavone have been extensively studied, and it has been shown to possess a wide range of therapeutic properties. One of the most notable aspects of this compound is its antioxidant activity. Antioxidants play a crucial role in neutralizing free radicals, which are known to cause cellular damage and contribute to various diseases, including cancer and neurodegenerative disorders. Recent studies have demonstrated that 7-Hydroxyflavone can effectively scavenge free radicals and protect cells from oxidative stress.
In addition to its antioxidant properties, 7-Hydroxyflavone has also been investigated for its anti-inflammatory effects. Inflammation is a complex biological response to harmful stimuli, such as pathogens or damaged cells, and chronic inflammation is associated with numerous diseases, including arthritis and cardiovascular disease. Research has shown that 7-Hydroxyflavone can inhibit the production of pro-inflammatory cytokines and reduce inflammation in both in vitro and in vivo models.
The neuroprotective potential of 7-Hydroxyflavone has also been a focus of recent studies. Neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are characterized by the progressive loss of neurons and cognitive decline. Preclinical studies have indicated that 7-Hydroxyflavone can protect neurons from damage caused by oxidative stress and beta-amyloid toxicity, which are key factors in the pathogenesis of Alzheimer's disease. Furthermore, it has been shown to enhance cognitive function in animal models of neurodegenerative diseases.
Beyond its direct biological activities, 7-Hydroxyflavone has also been explored for its potential as a drug delivery platform. Flavonoids, including 7-Hydroxyflavone, can be encapsulated in nanoparticles or liposomes to improve their bioavailability and target specific tissues or organs. This approach has shown promise in enhancing the therapeutic efficacy of these compounds while reducing side effects.
The safety profile of 7-Hydroxyflavone is another important aspect that has been evaluated in various studies. Toxicological assessments have generally indicated that this compound is well-tolerated at therapeutic doses, with minimal adverse effects observed in both animal and human studies. However, as with any bioactive compound, it is essential to conduct thorough safety evaluations before considering its use in clinical settings.
In conclusion, 7-Hydroxyflavone (CAS No. 6665-86-7) is a multifaceted compound with a wide range of biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties. Its potential applications in the treatment of various diseases make it an exciting area of research for scientists and clinicians alike. Ongoing studies continue to uncover new insights into the mechanisms underlying its therapeutic effects, paving the way for its potential use in future therapeutic strategies.
