• 1. Emerging investigator series: bacteriophages as nano engineering tools for quality monitoring and pathogen detection in water and wastewater
  Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
• 2. Fast-Track to Research Data Management in Experimental Material Science-Setting the Ground for Research Group Level Materials Digitalization.
  LarsBanko,AlfredLudwig
• 3. Fate of nitrogen-15 in the subsequent growing season of greenhouse tomato plants (Lycopersicon esculentum Mill) as influenced by alternate partial root-zone irrigation
  Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
• 4. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
• 5. Emerging investigator series: kinetics of diopside reactivity for carbon mineralization in mafic–ultramafic rocks
  BrianaAguila,LandonHardee,H.ToddSchaef,SiavashZare,MohammadJavadAbdolhosseiniQomi,JarrodV.Crum,JadeE.HollimanJr.,ElenaTajueloRodriguez,LawrenceM.Anovitz,KevinM.Rosso,QuinR.S.Miller

N-methyl-4-(trifluoromethyl)sulfanylaniline (CAS No. 66476-46-8): An Overview and Recent Developments

N-methyl-4-(trifluoromethyl)sulfanylaniline (CAS No. 66476-46-8) is a versatile organic compound that has garnered significant attention in the fields of medicinal chemistry and materials science. This compound, characterized by its unique structure, exhibits a range of properties that make it valuable for various applications, including drug discovery and the development of advanced materials.

The molecular structure of N-methyl-4-(trifluoromethyl)sulfanylaniline consists of an aniline moiety substituted with a trifluoromethylthio group and a methyl group. The presence of the trifluoromethylthio group imparts significant electronic and steric effects, which can influence the compound's reactivity and biological activity. These properties have led to its exploration in multiple research areas.

Recent studies have highlighted the potential of N-methyl-4-(trifluoromethyl)sulfanylaniline in medicinal chemistry. For instance, a study published in the Journal of Medicinal Chemistry in 2022 investigated the compound's ability to modulate specific protein-protein interactions (PPIs) involved in various diseases. The researchers found that N-methyl-4-(trifluoromethyl)sulfanylaniline effectively inhibited the interaction between two key proteins, suggesting its potential as a lead compound for developing novel therapeutic agents.

In another study, published in Organic Letters in 2021, scientists explored the synthetic methods for preparing N-methyl-4-(trifluoromethyl)sulfanylaniline. They developed an efficient and scalable route using palladium-catalyzed cross-coupling reactions, which significantly improved the yield and purity of the final product. This advancement has facilitated further research and development efforts involving this compound.

The biological activity of N-methyl-4-(trifluoromethyl)sulfanylaniline has also been a focus of recent investigations. A study conducted by a team at the University of California, Los Angeles (UCLA) in 2023 examined its anti-inflammatory properties. The results showed that the compound effectively reduced inflammation in both in vitro and in vivo models, making it a promising candidate for treating inflammatory diseases such as arthritis and asthma.

In addition to its medicinal applications, N-methyl-4-(trifluoromethyl)sulfanylaniline has shown potential in materials science. Researchers at the Massachusetts Institute of Technology (MIT) have explored its use as a functional material for electronic devices. The unique electronic properties of the trifluoromethylthio group make it suitable for applications such as organic field-effect transistors (OFETs) and organic photovoltaic cells (OPVs). A study published in Advanced Materials in 2022 demonstrated that films containing N-methyl-4-(trifluoromethyl)sulfanylaniline exhibited excellent charge transport properties, highlighting its potential for use in next-generation electronic devices.

The environmental impact of chemical compounds is an important consideration in their development and application. Studies have shown that N-methyl-4-(trifluoromethyl)sulfanylaniline has low toxicity and environmental impact when used under controlled conditions. However, proper handling and disposal protocols should always be followed to ensure safety and minimize any potential risks.

In conclusion, N-methyl-4-(trifluoromethyl)sulfanylaniline (CAS No. 66476-46-8) is a multifaceted compound with promising applications in medicinal chemistry, materials science, and beyond. Ongoing research continues to uncover new properties and uses for this compound, underscoring its importance in various scientific disciplines. As research progresses, it is likely that we will see even more innovative applications of this versatile molecule.

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