Cas no 66215-27-8 (Cyromazine)

Cyromazine is a triazine-class insect growth regulator (IGR) widely used in agriculture and veterinary applications. It acts by inhibiting larval development in target insects, particularly dipteran species such as flies and leafminers, through interference with cuticle formation and molting processes. Its selective mode of action ensures minimal impact on non-target organisms, including beneficial insects and mammals. Cyromazine exhibits systemic and translaminar activity, providing residual protection in crops and livestock environments. It is effective at low application rates and demonstrates strong stability under varying environmental conditions. The compound is commonly formulated as soluble concentrates or granules, offering flexibility in application methods. Resistance management programs often incorporate cyromazine due to its distinct biochemical target.
Cyromazine structure
Cyromazine structure
Product Name:Cyromazine
CAS No:66215-27-8
MF:C6H10N6
MW:166.183799266815
MDL:MFCD00078650
CID:58443
PubChem ID:47866
Update Time:2026-05-14

Cyromazine Chemical and Physical Properties

Names and Identifiers

    • Cyromazine
    • 2-cyclopropylamino-4,6-diamino-s-triazine
    • ARMOR
    • ARMOR(R)
    • cyclopropyl-1,3,5-triazine-2,4,6-triamine
    • Cyclopropylmelamine
    • CYPROMAZINE
    • CYROMAZIN
    • Cyromazin solution
    • 2-N-cyclopropyl-1,3,5-triazine-2,4,6-triamine
    • Cyromazine Solution
    • N<sup>2</sup>-Cyclopropyl-1,3,5-triazine-2,4,6-triamine
    • N-CYCLOPROPY-1,3,5-TRIAZIN-2,4,6-TRIAMINE
    • 2,4-diamino-6-cyclopropylamino-1,3,5-triazine
    • 2,4-diamino-6-cyclopropylamino-s-triazine
    • Azimethiphos
    • CGA-72662
    • Citation
    • Larvadex
    • N1-cyclopropyl-1,3,5-triazine-2,4,6-triamine
    • N-cyclopropyl-1,3,5-triazine-2,4,6-triamine
    • Neporex
    • Trigard
    • Vetrazin
    • Vetrazine
    • N2-Cyclopropylmelamine
    • 2,4-Diamino-6-(cyclopropylamino)-1,3,5-triazine
    • Diamino-6-(cyclopropylamino)-s-triazine
    • Larvade
    • OMS-2014
    • N-cyclopropylmelamine
    • Vetrazin (pesticide)
    • Cga 72662
    • Cyromazinum
    • Ciromazina
    • 1,3,5-Triazine-2,4,6-triamine, N-cyclopropyl-
    • Larvadex Premix
    • N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine
    • Caswell No. 167B
    • Cyromazine [BAN:INN]
    • Cyromazinum [INN-Latin]
    • C
    • MDL: MFCD00078650
    • Inchi: 1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)
    • InChI Key: LVQDKIWDGQRHTE-UHFFFAOYSA-N
    • SMILES: N([H])(C1N=C(N([H])[H])N=C(N([H])[H])N=1)C1([H])C([H])([H])C1([H])[H]

Computed Properties

  • Exact Mass: 166.09700
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 148
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.2
  • Topological Polar Surface Area: 103
  • Surface Charge: 0
  • Tautomer Count: 10

Experimental Properties

  • Color/Form: Powder
  • Density: 1.3196 (rough estimate)
  • Melting Point: 223-227?°C (lit.)
  • Boiling Point: 284.39°C (rough estimate)
  • Flash Point: Fahrenheit: 212 ° f
    Celsius: 100 ° c
  • Refractive Index: 1.8300 (estimate)
  • PSA: 102.74000
  • LogP: 0.84570
  • Merck: 2775
  • Solubility: Not determined

Cyromazine Security Information

  • Symbol: GHS07
  • Prompt:warning
  • Signal Word:Warning
  • Hazard Statement: H315,H319,H332,H335
  • Warning Statement: P261,P305+P351+P338
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:2
  • Hazard Category Code: 36/37/38
  • Safety Instruction: S26-S36
  • RTECS:XZ1056500
  • Hazardous Material Identification: Xi
  • Storage Condition:Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
  • Risk Phrases:R36/37/38

Cyromazine Customs Data

  • HS CODE:2933699015
  • Customs Data:

    China Customs Code:

    2933699015

    Overview:

    2933699015 Pirimiphos,cyromazine ,Pymetrozine, etc. [including carbendazim] Tax refund rate:9.0% Regulatory conditions:S(Import and Export Pesticide Registration Certificate)

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Regulatory conditions:

    S.Import and Export Pesticide Registration Certificate

    Summary:

    2933699015 4,6-dichloro-n-(2-chlorophenyl)-1,3,5-triazin-2-amine.supervision conditions:s(import or export registration certificate for pesticides).VAT:17.0%.tax rebate rate:9.0%.MFN tarrif:6.5%.general tariff:20.0%

Cyromazine Pricemore >>

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Cyromazine Production Method

Cyromazine Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:66215-27-8)Cyromazine
Order Number:LE5554;LE10846
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:47
Price ($):discuss personally
Suzhou Senfeida Chemical Co., Ltd
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(CAS:66215-27-8)Cyromazine
Order Number:sfd4419
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:33
Price ($):discuss personally
Jiangsu Xinsu New Materials Co., Ltd
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(CAS:66215-27-8)
Order Number:SFD1464
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Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Wednesday, 11 December 2024 17:02
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Cyromazine Spectrogram

13C NMR
13C NMR
1H NMR 300 MHz DMSO
1H NMR

Additional information on Cyromazine

Introduction to Cyromazine (CAS No. 66215-27-8) in Modern Chemical and Pharmaceutical Applications

Cyromazine, a compound with the chemical identifier CAS No. 66215-27-8, has emerged as a significant molecule in the realm of chemical and pharmaceutical research. This organochlorine derivative is primarily recognized for its utility as an insect growth regulator, but its applications extend far beyond traditional agricultural uses. In recent years, the compound has garnered attention for its potential in therapeutic interventions and as a key intermediate in the synthesis of novel pharmaceutical agents.

The molecular structure of Cyromazine consists of a chlorinated benzene ring fused with a pyrazine moiety, which contributes to its unique chemical properties. This configuration allows it to interact with biological systems in distinct ways, making it a versatile candidate for various scientific explorations. The compound's mode of action primarily involves the inhibition of chitin synthesis in insects, thereby disrupting their development and reproductive cycles.

Recent studies have delved into the pharmacological properties of Cyromazine, revealing its potential as an anti-inflammatory agent. Research indicates that Cyromazine can modulate certain inflammatory pathways by inhibiting the activity of key enzymes such as lipoxygenase and cyclooxygenase. These findings have opened new avenues for exploring its therapeutic applications in conditions characterized by excessive inflammation, such as rheumatoid arthritis and inflammatory bowel disease.

In addition to its anti-inflammatory potential, Cyromazine has shown promise in the field of oncology. Preliminary research suggests that the compound can induce apoptosis in certain cancer cell lines by disrupting mitochondrial function and impairing DNA replication. These effects are particularly notable in breast cancer and leukemia cells, where Cyromazine has demonstrated selective toxicity. Further investigation is warranted to fully elucidate its mechanisms of action and optimize its use as an anticancer therapeutic.

The synthesis of Cyromazine involves a series of well-defined chemical reactions that highlight its importance as an intermediate in organic chemistry. The process typically begins with the chlorination of a pyrazine derivative, followed by functional group transformations that introduce the characteristic benzene ring structure. Advanced synthetic methodologies have been developed to enhance yield and purity, ensuring that the final product meets stringent quality standards required for pharmaceutical applications.

The environmental impact of Cyromazine is another critical aspect that has been extensively studied. Unlike traditional insecticides that persist in the environment for extended periods, Cyromazine exhibits relatively low persistence and high biodegradability. This property makes it an environmentally friendly alternative for pest control while minimizing ecological risks. Field studies have demonstrated that Cyromazine breaks down rapidly into non-toxic metabolites, reducing long-term environmental contamination.

Regulatory considerations play a pivotal role in the utilization of Cyromazine across different sectors. In agriculture, its registration with agencies such as the Environmental Protection Agency (EPA) ensures that it is used safely and effectively. The compound's low toxicity profile to non-target organisms further supports its widespread adoption in integrated pest management systems. In pharmaceutical contexts, rigorous testing and compliance with Good Manufacturing Practices (GMP) are essential to ensure patient safety and efficacy.

The future prospects of Cyromazine are promising, with ongoing research aiming to expand its applications beyond current domains. Innovations in drug delivery systems are being explored to enhance the bioavailability and targeted action of Cyromazine-based formulations. Additionally, collaborations between academic institutions and pharmaceutical companies are fostering novel approaches to harnessing its therapeutic potential.

In conclusion, Cyromazine (CAS No. 66215-27-8) stands as a remarkable compound with diverse applications in agriculture and medicine. Its unique chemical properties, coupled with recent advancements in research, position it as a cornerstone molecule in modern chemical and pharmaceutical sciences. As scientific understanding continues to evolve, the full spectrum of Cyromazine's capabilities is expected to be uncovered, paving the way for innovative solutions across multiple disciplines.

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:66215-27-8)Cyromazine
LE5554;LE10846
Purity:99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry
Email
Suzhou Senfeida Chemical Co., Ltd
(CAS:66215-27-8)Cyromazine
sfd4419
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email