Cas no 662146-05-6 (4-Fluoro-3-methyl-1H-indazole)
4-Fluoro-3-methyl-1H-indazole is a fluorinated heterocyclic compound featuring an indazole core substituted with a fluorine atom at the 4-position and a methyl group at the 3-position. This structure imparts unique reactivity and potential utility in pharmaceutical and agrochemical research, particularly as a building block for the synthesis of biologically active molecules. The fluorine substitution enhances metabolic stability and binding affinity in target interactions, while the methyl group offers steric and electronic modulation. Its high purity and well-defined chemical properties make it a valuable intermediate for medicinal chemistry applications, including kinase inhibitor development and other therapeutic agents. Suitable for controlled reactions under standard laboratory conditions.
4-Fluoro-3-methyl-1H-indazole structure
Product Name:4-Fluoro-3-methyl-1H-indazole
CAS No:662146-05-6
MF:C8H7FN2
MW:150.152984857559
MDL:MFCD04109834
CID:963501
PubChem ID:2804705
Update Time:2025-10-29
4-Fluoro-3-methyl-1H-indazole Chemical and Physical Properties
Names and Identifiers
-
- 4-Fluoro-3-methyl-1H-indazole
- 1H-Indazole,4-fluoro-3-methyl-(9CI)
- 4-Fluoro-3-methyl-2H-indazole
- AC1MD2I3
- ANW-64291
- CCG-47017
- CTK8C0174
- SureCN3443437
- PTONAHDKOCUIPS-UHFFFAOYSA-N
- AKOS006295669
- 1H-INDAZOLE, 4-FLUORO-3-METHYL-
- KS-9835
- A857820
- SR-01000636675-1
- 4-fluoro-3-methyl-1h-indazol
- SCHEMBL3443437
- MFCD04109834
- DTXSID40384437
- DB-381186
- 1145777-43-0
- DB-412721
- MB03173
- 662146-05-6
-
- MDL： MFCD04109834
- Inchi： 1S/C8H7FN2/c1-5-8-6(9)3-2-4-7(8)11-10-5/h2-4H,1H3,(H,10,11)
- InChI Key： PTONAHDKOCUIPS-UHFFFAOYSA-N
- SMILES： FC1=CC=CC2C1=C(C)NN=2
Computed Properties
- Exact Mass: 150.05932639g/mol
- Monoisotopic Mass: 150.05932639g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 11
- Rotatable Bond Count: 0
- Complexity: 151
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.1
- Topological Polar Surface Area: 28.7?2
Experimental Properties
- Density: 1.3±0.1 g/cm3
- Boiling Point: 129.4±33.0 °C at 760 mmHg
- Flash Point: 32.1±25.4 °C
- Vapor Pressure: 10.2±0.2 mmHg at 25°C
4-Fluoro-3-methyl-1H-indazole Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
4-Fluoro-3-methyl-1H-indazole Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 230270-1g |
4-Fluoro-3-methyl-1H-indazole |
662146-05-6 | 95% | 1g |
￡525.00 | 2022-02-28 | |
| Chemenu | CM149939-5g |
4-Fluoro-3-methyl-1H-indazole |
662146-05-6 | 95% | 5g |
$830 | 2021-08-05 | |
| TRC | F600225-2.5mg |
4-Fluoro-3-methyl-1H-indazole |
662146-05-6 | 2.5mg |
$ 50.00 | 2022-06-04 | ||
| TRC | F600225-5mg |
4-Fluoro-3-methyl-1H-indazole |
662146-05-6 | 5mg |
$ 70.00 | 2022-06-04 | ||
| TRC | F600225-25mg |
4-Fluoro-3-methyl-1H-indazole |
662146-05-6 | 25mg |
$ 230.00 | 2022-06-04 | ||
| Chemenu | CM149939-1g |
4-Fluoro-3-methyl-1H-indazole |
662146-05-6 | 95% | 1g |
$*** | 2023-03-31 | |
| abcr | AB358886-1 g |
4-Fluoro-3-methyl-1H-indazole, 98%; . |
662146-05-6 | 98% | 1 g |
€467.00 | 2023-07-19 | |
| Apollo Scientific | PC402007-250mg |
4-Fluoro-3-methyl-1H-indazole |
662146-05-6 | 250mg |
￡450.00 | 2024-05-25 | ||
| eNovation Chemicals LLC | D516331-250mg |
1H-Indazole, 4-fluoro-3-methyl- |
662146-05-6 | 95% | 250mg |
$368 | 2024-06-05 | |
| eNovation Chemicals LLC | D516331-1g |
1H-Indazole, 4-fluoro-3-methyl- |
662146-05-6 | 95% | 1g |
$998 | 2024-06-05 |
4-Fluoro-3-methyl-1H-indazole Related Literature
-
Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
-
Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
-
Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
-
Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
-
Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
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