Cas no 66047-01-6 (Ethyl 2-(3-Methylphenoxy)acetate)

Ethyl 2-(3-Methylphenoxy)acetate is a synthetic ester compound characterized by its aromatic phenoxyacetate structure. It serves as a versatile intermediate in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and specialty chemicals. The presence of the 3-methylphenoxy moiety enhances its reactivity in etherification and esterification processes, while the ethyl ester group improves solubility in organic solvents. This compound is valued for its stability under standard conditions and its utility in constructing complex molecular frameworks. Its well-defined chemical properties make it suitable for controlled reactions in fine chemical manufacturing, ensuring consistent performance in synthetic applications.
Ethyl 2-(3-Methylphenoxy)acetate structure
66047-01-6 structure
Product Name:Ethyl 2-(3-Methylphenoxy)acetate
CAS No:66047-01-6
MF:C11H14O3
MW:194.227063655853
CID:396928
PubChem ID:13677600
Update Time:2025-11-02

Ethyl 2-(3-Methylphenoxy)acetate Chemical and Physical Properties

Names and Identifiers

    • Acetic acid, (3-methylphenoxy)-, ethyl ester
    • Ethyl 2-(3-Methylphenoxy)acetate
    • (3-METHYLPHENOXY) ACETIC ACID ETHYL ESTER
    • ethyl m-methylphenoxyacetate
    • m-Kresoxyessigsaeure-aethylester
    • m-tolyloxy-acetic acid ethyl ester
    • m-Tolyloxy-essigsaeure-aethylester
    • m-Tolyloxyethylacetat
    • ethyl2-(m-tolyloxy)acetate
    • 66047-01-6
    • CHEMBL1163910
    • Ethyl 3-methylphenoxyacetate
    • (3-METHYLPHENOXY)ACETICACIDETHYLESTER
    • FT-0695387
    • ETHYL (3-METHYLPHENOXY)ACETATE
    • (3-methylphenoxy)acetic acid ethyl ester
    • CS-0331453
    • DTXSID50546488
    • ethyl 2-(m-tolyloxy)acetate
    • SCHEMBL6494581
    • YITOTGGGSHWZDB-UHFFFAOYSA-N
    • BDBM50321270
    • AKOS008947814
    • AB08349
    • FS-5190
    • MDL: MFCD01162421
    • Inchi: 1S/C11H14O3/c1-3-13-11(12)8-14-10-6-4-5-9(2)7-10/h4-7H,3,8H2,1-2H3
    • InChI Key: YITOTGGGSHWZDB-UHFFFAOYSA-N
    • SMILES: O(CC(=O)OCC)C1=CC=CC(C)=C1

Computed Properties

  • Exact Mass: 194.09400
  • Monoisotopic Mass: 194.094294304g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 5
  • Complexity: 179
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.5
  • Topological Polar Surface Area: 35.5?2

Experimental Properties

  • PSA: 35.53000
  • LogP: 1.93690

Ethyl 2-(3-Methylphenoxy)acetate Customs Data

  • HS CODE:2918990090
  • Customs Data:

    China Customs Code:

    2918990090

    Overview:

    2918990090. Other additional oxy carboxylic acids(Including anhydrides\Acyl halide\Peroxides, peroxyacids and derivatives of this tax number). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Additional information on Ethyl 2-(3-Methylphenoxy)acetate

Ethyl 2-(3-Methylphenoxy)acetate (CAS No. 66047-01-6): Properties, Applications, and Market Insights

Ethyl 2-(3-Methylphenoxy)acetate (CAS No. 66047-01-6) is an organic ester compound widely used in the chemical and pharmaceutical industries. This compound, also known as ethyl 3-methylphenoxyacetate, is valued for its versatile applications, particularly as an intermediate in the synthesis of fragrances, flavors, and active pharmaceutical ingredients (APIs). Its molecular formula is C11H14O3, and it features a phenoxyacetate structure with an ethyl ester group, making it a key building block in organic synthesis.

The chemical properties of Ethyl 2-(3-Methylphenoxy)acetate include a clear to pale yellow liquid appearance, a characteristic mild aromatic odor, and moderate solubility in organic solvents such as ethanol, ether, and chloroform. Its boiling point ranges between 250-260°C, and it has a density of approximately 1.08 g/cm3. These properties make it suitable for various industrial applications, including the production of flavor and fragrance compounds, where it contributes to fruity and floral notes.

One of the most significant applications of Ethyl 2-(3-Methylphenoxy)acetate is in the pharmaceutical sector. Researchers and manufacturers utilize it as a precursor in the synthesis of APIs, particularly in the development of anti-inflammatory and analgesic drugs. The compound’s phenoxyacetate moiety is often incorporated into more complex molecular structures, enhancing drug efficacy and bioavailability. Additionally, its role in green chemistry and sustainable synthesis has gained attention, aligning with the growing demand for eco-friendly chemical processes.

In the flavor and fragrance industry, Ethyl 2-(3-Methylphenoxy)acetate is prized for its ability to impart sweet, berry-like aromas. It is commonly used in perfumes, cosmetics, and food flavorings, where its stability and low volatility ensure long-lasting scent profiles. With consumers increasingly favoring natural and synthetic aroma chemicals, this compound has seen rising demand in niche markets, including premium personal care products and gourmet food additives.

Market trends indicate a steady growth trajectory for Ethyl 2-(3-Methylphenoxy)acetate, driven by advancements in pharmaceutical research and the expanding flavor and fragrance sector. The compound’s compatibility with modern synthetic techniques, such as enzymatic catalysis and microwave-assisted reactions, further enhances its industrial relevance. As regulatory bodies emphasize safer chemical alternatives, manufacturers are exploring innovative production methods to reduce environmental impact while maintaining high purity standards.

From an SEO perspective, users frequently search for terms like "Ethyl 2-(3-Methylphenoxy)acetate uses", "CAS 66047-01-6 suppliers", and "3-methylphenoxyacetate synthesis". Addressing these queries, this article highlights the compound’s key applications, market dynamics, and future potential. Whether you are a researcher, procurement specialist, or industry enthusiast, understanding the multifaceted role of Ethyl 2-(3-Methylphenoxy)acetate can provide valuable insights into its commercial and scientific significance.

In conclusion, Ethyl 2-(3-Methylphenoxy)acetate (CAS No. 66047-01-6) remains a vital compound in organic synthesis, with broad applications in pharmaceuticals, flavors, and fragrances. Its unique chemical properties, combined with evolving industrial demands, position it as a key player in specialty chemicals. As innovation continues to shape the sector, this ester’s role in sustainable chemistry and high-value product development is expected to grow, making it a compound worth watching in the coming years.

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