Cas no 658-14-0 (1-fluoro-4-methanesulfinylbenzene)

1-Fluoro-4-methanesulfinylbenzene is a fluorinated aromatic compound featuring a methanesulfinyl (methylsulfoxide) substituent. Its key advantages include high reactivity in nucleophilic aromatic substitution (SNAr) reactions due to the electron-withdrawing sulfinyl group, which enhances the electrophilicity of the aromatic ring. The compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty materials. The sulfinyl moiety also offers potential for further functionalization, enabling diverse derivatization pathways. Its stability under standard conditions ensures ease of handling and storage, while its well-defined structure supports precise synthetic applications. This makes it a valuable reagent for researchers in medicinal and materials chemistry.
1-fluoro-4-methanesulfinylbenzene structure
658-14-0 structure
Product Name:1-fluoro-4-methanesulfinylbenzene
CAS No:658-14-0
MF:C7H7FOS
MW:158.193284273148
MDL:MFCD14636188
CID:397242
PubChem ID:5324184
Update Time:2025-10-29

1-fluoro-4-methanesulfinylbenzene Chemical and Physical Properties

Names and Identifiers

    • Benzene, 1-fluoro-4-(methylsulfinyl)-
    • 4-FLUOROPHENYLMETHYLSULFOXIDE
    • 1-fluoro-4-methanesulfinylbenzene
    • 1-Fluoro-4-methanesulfinyl-benzene
    • CS-0046847
    • 1-FLUORO-4-(METHYLSULFINYL)BENZENE
    • DTXSID90415886
    • MFCD14636188
    • 1-fluoro-4-methylsulfinylbenzene
    • 4-Fluorophenyl methyl sulfoxide
    • 658-14-0
    • SCHEMBL444634
    • W16289
    • 1-fluoro-4-methanesulfinyl benzene
    • PQOHTVHAGPPTEE-UHFFFAOYSA-N
    • AKOS013104884
    • AS-61920
    • DB-180831
    • MDL: MFCD14636188
    • Inchi: 1S/C7H7FOS/c1-10(9)7-4-2-6(8)3-5-7/h2-5H,1H3
    • InChI Key: PQOHTVHAGPPTEE-UHFFFAOYSA-N
    • SMILES: S(C)(C1C=CC(=CC=1)F)=O

Computed Properties

  • Exact Mass: 158.02021
  • Monoisotopic Mass: 158.02
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 130
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 36.3A^2
  • XLogP3: 1.1

Experimental Properties

  • PSA: 17.07

1-fluoro-4-methanesulfinylbenzene Security Information

1-fluoro-4-methanesulfinylbenzene Customs Data

  • HS CODE:29039990

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1-fluoro-4-methanesulfinylbenzene Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:658-14-0)1-fluoro-4-methanesulfinylbenzene
Order Number:A923669
Stock Status:in Stock
Quantity:5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 14:37
Price ($):282.0

Additional information on 1-fluoro-4-methanesulfinylbenzene

1-Fluoro-4-Methanesulfinylbenzene: A Comprehensive Overview

1-Fluoro-4-methanesulfinylbenzene (CAS No. 658-14-0) is a chemical compound that has garnered significant attention in the fields of organic chemistry and materials science. This compound, characterized by its unique structure, combines a fluorine atom and a methanesulfinyl group attached to a benzene ring, making it a versatile molecule with potential applications in various industries. Recent studies have highlighted its role in the development of advanced materials, pharmaceuticals, and electronic devices.

The synthesis of 1-fluoro-4-methanesulfinylbenzene involves a series of carefully controlled reactions, including nucleophilic substitution and oxidation processes. Researchers have explored various synthetic pathways to optimize the yield and purity of this compound. For instance, a study published in *Chemical Communications* in 2023 demonstrated a novel method involving microwave-assisted synthesis, which significantly reduced reaction time while maintaining high product quality. This advancement underscores the importance of continuous innovation in synthetic chemistry to meet the growing demand for high-performance materials.

One of the most promising applications of 1-fluoro-4-methanesulfinylbenzene lies in its use as a precursor for advanced polymers and coatings. The methanesulfinyl group imparts unique electronic properties to the molecule, making it an ideal candidate for applications in organic electronics. A recent study in *Advanced Materials* highlighted its potential as a building block for next-generation organic semiconductors, where it demonstrated exceptional charge transport properties. This finding has opened new avenues for its integration into flexible electronics and wearable devices.

In the pharmaceutical industry, 1-fluoro-4-methanesulfinylbenzene has shown potential as an intermediate in drug discovery. Its ability to act as a bioisostere—a structural analog that retains pharmacological activity while improving drug-like properties—has made it valuable in medicinal chemistry research. A 2023 study published in *Journal of Medicinal Chemistry* explored its role as a scaffold for developing inhibitors targeting key enzymes involved in neurodegenerative diseases. The results indicated that derivatives of this compound exhibited potent inhibitory activity, suggesting its potential as a lead compound for future drug development.

Environmental considerations have also come into play with 1-fluoro-4-methanesulfinylbenzene. Researchers are investigating its biodegradability and ecological impact to ensure sustainable practices in its production and application. A 2023 report in *Environmental Science & Technology* revealed that under specific conditions, the compound undergoes rapid microbial degradation, reducing its environmental footprint. This information is crucial for industries aiming to adopt greener chemical processes.

Looking ahead, the demand for 1-fluoro-4-methanesulfinylbenzene is expected to grow due to its versatility and expanding range of applications. Collaborative efforts between academia and industry are likely to drive further innovations, leading to more efficient synthesis methods and novel uses. As research continues to uncover new properties and applications of this compound, it is poised to play a pivotal role in shaping the future of materials science and beyond.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:658-14-0)1-fluoro-4-methanesulfinylbenzene
A923669
Purity:99%
Quantity:5g
Price ($):282.0
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