Cas no 65676-21-3 (Chlorpheniramine Nitrile)

Chlorpheniramine Nitrile is a key intermediate in the synthesis of chlorpheniramine, an antihistamine widely used in pharmaceutical formulations. This nitrile derivative offers high reactivity and selectivity, facilitating efficient downstream transformations in active pharmaceutical ingredient (API) production. Its stable chemical structure ensures consistent performance in synthetic processes, while its purity and compatibility with common reagents make it a reliable choice for industrial-scale manufacturing. The compound’s well-defined properties enable precise control over reaction conditions, contributing to improved yields and reduced byproducts. As a critical building block, Chlorpheniramine Nitrile supports the production of antihistamine drugs with standardized quality and efficacy.
Chlorpheniramine Nitrile structure
Chlorpheniramine Nitrile structure
Product Name:Chlorpheniramine Nitrile
CAS No:65676-21-3
MF:C17H18ClN3
MW:299.797922611237
CID:962319
PubChem ID:103434
Update Time:2025-10-19

Chlorpheniramine Nitrile Chemical and Physical Properties

Names and Identifiers

    • alpha-(4-chlorophenyl)-alpha-[2-(dimethylamino)ethyl]pyridine-2-acetonitrile
    • Chlorpheniramine Nitrile
    • 2-(4-chloro-phenyl)-4-dimethylamino-2-[2]pyridyl-butyronitrile
    • 2-(4-Chlor-phenyl)-4-dimethylamino-2-[2]pyridyl-butyronitril
    • A-(2-(dimethylamino)ethyl)pyridine-2-acetonitrile
    • A-(4-chlorophenyl)-
    • AC1L2URU
    • AC1Q3NA0
    • AG-G-47246
    • AR-1L8468
    • chloropheniramine nitrile
    • CTK2F6710
    • EINECS 265-869-2
    • 65676-21-3
    • XWFSLFHFPQWKNV-UHFFFAOYSA-N
    • CHLORPHENAMINE MALEATE IMPURITY D [EP IMPURITY]
    • 2-PYRIDINEACETONITRILE, .ALPHA.-(P-CHLOROPHENYL)-.ALPHA.-(2-(DIMETHYLAMINO)ETHYL)-
    • (2RS)-2-(4-chlorophenyl)-4-(dimethylamino)-2-(pyridin-2-yl)butanenitrile
    • 92618CMY2O
    • ChlorpheniramineNitrile-d6
    • CHLORPHENIRAMINE NITRILE [USP IMPURITY]
    • NS00056782
    • UNII-92618CMY2O
    • 2-PYRIDINEACETONITRILE, .ALPHA.-(4-CHLOROPHENYL)-.ALPHA.-(2-(DIMETHYLAMINO)ETHYL)-
    • 2-(4-CHLOROPHENYL)-4-(DIMETHYLAMINO)-2-(PYRIDIN-2-YL)BUTANENITRILE
    • DTXSID50984225
    • 2-(4-chlorophenyl)-4-(dimethylamino)-2-pyridin-2-ylbutanenitrile
    • Q27271478
    • alpha-(4-Chlorophenyl)-alpha-(2-(dimethylamino)ethyl)pyridine-2-acetonitrile
    • a-(4-Chlorophenyl)-a-[2-(dimethylamino)ethyl]-2-pyridineacetonitrile; a-(p-Chlorophenyl)-a-[2-(dimethylamino)ethyl]-2-pyridineacetonitrile; Chlorpeniramine EP Impurity D;
    • Inchi: 1S/C17H18ClN3/c1-21(2)12-10-17(13-19,16-5-3-4-11-20-16)14-6-8-15(18)9-7-14/h3-9,11H,10,12H2,1-2H3
    • InChI Key: XWFSLFHFPQWKNV-UHFFFAOYSA-N
    • SMILES: ClC1C=CC(=CC=1)C(C#N)(C1C=CC=CN=1)CCN(C)C

Computed Properties

  • Exact Mass: 299.1189253g/mol
  • Monoisotopic Mass: 299.1189253g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 21
  • Rotatable Bond Count: 5
  • Complexity: 368
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.1
  • Topological Polar Surface Area: 39.9?2

Chlorpheniramine Nitrile Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
C424315-25mg
Chlorpheniramine Nitrile
65676-21-3
25mg
$ 221.00 2023-09-08
TRC
C424315-250mg
Chlorpheniramine Nitrile
65676-21-3
250mg
$ 1742.00 2023-09-08
SHENG KE LU SI SHENG WU JI SHU
sc-394455-25 mg
Chlorpheniramine Nitrile,
65676-21-3
25mg
¥2,708.00 2023-07-10
SHENG KE LU SI SHENG WU JI SHU
sc-394455-25mg
Chlorpheniramine Nitrile,
65676-21-3
25mg
¥2708.00 2023-09-05
A2B Chem LLC
AH17117-50mg
2-(4-Chlorophenyl)-4-(dimethylamino)-2-(pyridin-2-yl)butanenitrile
65676-21-3 > 95%
50mg
$423.00 2024-04-19
A2B Chem LLC
AH17117-25mg
2-(4-Chlorophenyl)-4-(dimethylamino)-2-(pyridin-2-yl)butanenitrile
65676-21-3
25mg
$319.00 2023-12-30
A2B Chem LLC
AH17117-250mg
2-(4-Chlorophenyl)-4-(dimethylamino)-2-(pyridin-2-yl)butanenitrile
65676-21-3
250mg
$1688.00 2023-12-30

Chlorpheniramine Nitrile Suppliers

SHOCHEM(SHANGHAI) CO.,lTD
Gold Member
Audited Supplier Audited Supplier
(CAS:65676-21-3)(2RS)-2-(4-chlorophenyl)-4-(dimethylamino)-2-(pyridin-2-yl)butanenitrile
Order Number:0101
Stock Status:in Stock
Quantity:100mg;500mg;1g
Purity:98%min
Pricing Information Last Updated:Thursday, 21 August 2025 16:52
Price ($):
Recommended suppliers
SHOCHEM(SHANGHAI) CO.,lTD
(CAS:65676-21-3)(2RS)-2-(4-chlorophenyl)-4-(dimethylamino)-2-(pyridin-2-yl)butanenitrile
0101
Purity:98%min
Quantity:100mg;500mg;1g
Price ($):Inquiry
Email