Cas no 651035-90-4 ((R)-tert-Butyl (1-chloro-3-hydroxypropan-2-yl)carbamate)
(R)-tert-Butyl (1-chloro-3-hydroxypropan-2-yl)carbamate is a chiral intermediate widely used in organic synthesis and pharmaceutical applications. Its key advantages include high enantiomeric purity, which is critical for asymmetric synthesis, and the presence of both hydroxyl and chloro functional groups, enabling versatile derivatization. The tert-butyloxycarbonyl (Boc) protecting group enhances stability and facilitates selective deprotection under mild acidic conditions. This compound is particularly valuable in the synthesis of bioactive molecules, such as β-amino alcohols and peptidomimetics. Its well-defined stereochemistry ensures consistent performance in stereoselective reactions, making it a reliable choice for researchers in medicinal chemistry and drug development.
651035-90-4 structure
Product Name:(R)-tert-Butyl (1-chloro-3-hydroxypropan-2-yl)carbamate
CAS No:651035-90-4
MF:C8H16ClNO3
MW:209.670541763306
CID:502139
PubChem ID:12184455
Update Time:2025-05-27
(R)-tert-Butyl (1-chloro-3-hydroxypropan-2-yl)carbamate Chemical and Physical Properties
Names and Identifiers
-
- (R)-tert-Butyl (1-chloro-3-hydroxypropan-2-yl)carbamate
- Carbamic acid, [(1R)-2-chloro-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester
- Carbamicacid, [(1R)-2-chloro-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester (9CI)
- TERT-BUTYL (1R)-2-CHLORO-1-(HYDROXYMETHYL)ETHYL CARBAMATE
- tert-butyl N-[(2R)-1-chloro-3-hydroxypropan-2-yl]carbamate
- (2-(R)-chloro-1-hydroxymethyl-ethyl)-carbamic acid tert-butyl ester
- (2-chloro-1-hydroxymethylethyl)carbamic acid tert-butyl ester
- (2-chloro-1-hydroxymethyl-ethyl)-carbamic acid tert-butyl ester
- AK111016
- I14-31881
- KB-210453
- tert-butyl [(2R)-1-chloro-3-hydroxypropan-2-yl]carbamate
- AKOS015909741
- tert-butyl[(2R)-1-chloro-3-hydroxypropan-2-yl]carbamate
- UVUHZZFYJGGEFI-LURJTMIESA-N
- SCHEMBL10080533
- 651035-90-4
- Carbamicacid,[(1R)-2-chloro-1-(hydroxymethyl)ethyl]-,1,1-dimethylethyl ester(9ci)
- CS-0454594
- tert-butyl (R)-(1-chloro-3-hydroxypropan-2-yl)carbamate
- DTXSID90479564
- (R)-TERT-BUTYL(1-CHLORO-3-HYDROXYPROPAN-2-YL)CARBAMATE
- DB-336276
-
- Inchi： 1S/C8H16ClNO3/c1-8(2,3)13-7(12)10-6(4-9)5-11/h6,11H,4-5H2,1-3H3,(H,10,12)/t6-/m0/s1
- InChI Key： UVUHZZFYJGGEFI-LURJTMIESA-N
- SMILES： ClC[C@@H](CO)NC(=O)OC(C)(C)C
Computed Properties
- Exact Mass: 209.08200
- Monoisotopic Mass: 209.0818711g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 13
- Rotatable Bond Count: 6
- Complexity: 167
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0.9
- Topological Polar Surface Area: 58.6?2
Experimental Properties
- PSA: 58.56000
- LogP: 1.50170
(R)-tert-Butyl (1-chloro-3-hydroxypropan-2-yl)carbamate Customs Data
- HS CODE：2924199090
- Customs Data：
China Customs Code:
2924199090Overview:
2924199090. Other acyclic amides(Including acyclic carbamates)(Including its derivatives and salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%
Declaration elements:
Product Name, component content, use to, packing
Summary:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
(R)-tert-Butyl (1-chloro-3-hydroxypropan-2-yl)carbamate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | T92680-0.5g |
Tert-butyl N-[(2R)-1-chloro-3-hydroxypropan-2-yl]carbamate |
651035-90-4 | 97% | 0.5g |
￥2529.0 | 2024-07-18 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | T92680-0.25g |
Tert-butyl N-[(2R)-1-chloro-3-hydroxypropan-2-yl]carbamate |
651035-90-4 | 97% | 0.25g |
￥1659.0 | 2024-07-18 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | T92680-1g |
Tert-butyl N-[(2R)-1-chloro-3-hydroxypropan-2-yl]carbamate |
651035-90-4 | 97% | 1g |
￥4029.0 | 2024-07-18 | |
| Chemenu | CM184533-1g |
tert-butyl (R)-(1-chloro-3-hydroxypropan-2-yl)carbamate |
651035-90-4 | 95% | 1g |
$*** | 2023-05-29 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1525261-1g |
Tert-butyl (R)-(1-chloro-3-hydroxypropan-2-yl)carbamate |
651035-90-4 | 98% | 1g |
￥7221.00 | 2024-05-05 |
(R)-tert-Butyl (1-chloro-3-hydroxypropan-2-yl)carbamate Related Literature
-
Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
-
Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
-
Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
-
Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
-
Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
651035-90-4 ((R)-tert-Butyl (1-chloro-3-hydroxypropan-2-yl)carbamate) Related Products
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
- 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
- 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
- 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
- 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
- 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)
Recommended suppliers
PRIBOLAB PTE.LTD
Gold Member
Audited Supplier
CN Supplier
Reagent
上海帛亦醫(yī)藥科技有限公司
Gold Member
Audited Supplier
CN Supplier
Reagent
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Reagent
