Cas no 648921-37-3 (3,3-Dimethylpiperidin-4-one hydrochloride)

3,3-Dimethylpiperidin-4-one hydrochloride is a versatile organic compound featuring a piperidinone core with dimethyl substitution at the 3-position. Its hydrochloride salt form enhances stability and solubility, making it suitable for synthetic applications in pharmaceutical and agrochemical research. The ketone functionality at the 4-position offers reactivity for further derivatization, while the quaternary carbon center contributes to structural rigidity. This compound is particularly valuable as a building block for the synthesis of biologically active molecules, including potential drug candidates. Its well-defined crystalline structure ensures consistent purity, facilitating reproducible results in experimental workflows. The compound is typically handled under standard laboratory conditions, with appropriate precautions for hygroscopic materials.
3,3-Dimethylpiperidin-4-one hydrochloride structure
648921-37-3 structure
Product Name:3,3-Dimethylpiperidin-4-one hydrochloride
CAS No:648921-37-3
MF:C7H14ClNO
MW:163.645161151886
MDL:MFCD11043097
CID:412312
PubChem ID:57358418
Update Time:2025-11-02

3,3-Dimethylpiperidin-4-one hydrochloride Chemical and Physical Properties

Names and Identifiers

    • 4-Piperidinone, 3,3-dimethyl-, hydrochloride
    • 3,3-Dimethyl-4-piperidone Hydrochloride
    • 3,3-DIMETHYLPIPERIDIN-4-ONE HYDROCHLORIDE
    • 3,3-dimethyl-4-oxopiperidium chloride
    • 3,3-DIMETHYLPIPERIDIN-4-ONE HCL
    • 3,3-DIMETHYL-PIPERIDIN-4-ONE HCL SALT
    • AK154223
    • 3,3-Dimethyl-piperidin-4-one hydrochloride
    • 3,3-DIMETHYL-PIPERIDIN-4-ONEHCLSALT
    • YKKXZGNFWDQKGO-UHFFFAOYSA-N
    • 2067AJ
    • TRA0020048
    • PB31517
    • SY031977
    • 3,3-dimethylpiperidin-4-one;hydrochloride
    • AX8081416
    • AB0082372
    • Q-
    • FT-0729807
    • 3,3-Dimethylpiperidin-4-one hydrochloride, AldrichCPR
    • 3,3-Dimethyl-4-piperidoneHydrochloride
    • CS-0019268
    • AKOS024260563
    • A867794
    • DTXSID00724113
    • 3 pound not3-Dimethyl-4-piperidone Hydrochloride
    • 3,3-Dimethylpiperidin-4-one--hydrogen chloride (1/1)
    • MFCD11043097
    • 648921-37-3
    • AS-42280
    • DA-24796
    • 3,3-Dimethyl-4-piperidinone hydrochloride (1:1)
    • 3,3-Dimethylpiperidin-4-one hydrochloride
    • MDL: MFCD11043097
    • Inchi: 1S/C7H13NO.ClH/c1-7(2)5-8-4-3-6(7)9;/h8H,3-5H2,1-2H3;1H
    • InChI Key: YKKXZGNFWDQKGO-UHFFFAOYSA-N
    • SMILES: Cl.O=C1CCNCC1(C)C

Computed Properties

  • Exact Mass: 163.07600
  • Monoisotopic Mass: 163.0763918g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 0
  • Complexity: 129
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 29.1

Experimental Properties

  • PSA: 29.10000
  • LogP: 1.70580

3,3-Dimethylpiperidin-4-one hydrochloride Pricemore >>

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3,3-Dimethylpiperidin-4-one hydrochloride Production Method

Additional information on 3,3-Dimethylpiperidin-4-one hydrochloride

Comprehensive Guide to 3,3-Dimethylpiperidin-4-one hydrochloride (CAS No. 648921-37-3): Properties, Applications, and Market Insights

3,3-Dimethylpiperidin-4-one hydrochloride (CAS No. 648921-37-3) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This white to off-white crystalline powder is widely recognized for its role as a key intermediate in the synthesis of various bioactive molecules. With the growing demand for novel drug candidates and fine chemicals, understanding the properties and applications of 3,3-Dimethylpiperidin-4-one HCl becomes crucial for researchers and industry professionals.

The compound belongs to the class of piperidine derivatives, which are known for their structural versatility in medicinal chemistry. Its molecular formula is C7H14ClNO, and it typically appears as a crystalline solid with good solubility in water and polar organic solvents. The hydrochloride salt form enhances its stability and makes it more suitable for various synthetic applications compared to the free base form.

Recent trends in pharmaceutical research have highlighted the importance of nitrogen-containing heterocycles like 3,3-Dimethylpiperidin-4-one in drug discovery. Many researchers are searching for information about "piperidine derivatives in drug development" or "building blocks for pharmaceutical synthesis," reflecting the compound's relevance in current scientific investigations. The presence of both ketone and amine functional groups in its structure makes it particularly valuable for creating diverse molecular architectures.

In synthetic applications, 3,3-Dimethylpiperidin-4-one hydrochloride serves as a versatile precursor for numerous transformations. It can undergo reactions such as reductive amination, nucleophilic addition, and condensation, making it valuable for constructing complex molecules. The pharmaceutical industry frequently utilizes this compound in the synthesis of potential drug candidates targeting neurological disorders and other therapeutic areas.

The global market for pharmaceutical intermediates like 3,3-Dimethylpiperidin-4-one HCl has shown steady growth, driven by increasing R&D investments in drug discovery. Market analysts often track searches for "specialty chemicals market trends" and "high-value chemical intermediates," indicating strong commercial interest in such compounds. Manufacturers are focusing on developing efficient synthetic routes to meet the growing demand while maintaining high purity standards.

Quality control is paramount when working with 3,3-Dimethylpiperidin-4-one hydrochloride. Analytical techniques such as HPLC, NMR spectroscopy, and mass spectrometry are routinely employed to verify the compound's identity and purity. Researchers frequently inquire about "analytical methods for piperidine derivatives" and "characterization of pharmaceutical intermediates," emphasizing the need for reliable quality assessment protocols.

From a safety perspective, proper handling procedures should always be followed when working with 3,3-Dimethylpiperidin-4-one hydrochloride. While not classified as hazardous under normal conditions, standard laboratory precautions are recommended. The scientific community shows consistent interest in topics like "safe handling of chemical intermediates" and "storage conditions for sensitive compounds," reflecting the importance of workplace safety in chemical research.

The future outlook for 3,3-Dimethylpiperidin-4-one hydrochloride appears promising, particularly in the context of drug discovery innovations. With increasing interest in "novel synthetic methodologies" and "green chemistry approaches," researchers are exploring more sustainable ways to utilize such intermediates. The compound's structural features continue to make it valuable for developing new therapeutic agents and functional materials.

For researchers considering 648921-37-3 for their projects, it's important to source the material from reputable suppliers who can provide comprehensive technical data and certificates of analysis. Common search queries like "reliable suppliers of specialty chemicals" and "technical specifications for research compounds" highlight the procurement considerations in scientific work. Proper documentation and regulatory compliance are essential aspects of working with such specialized materials.

In conclusion, 3,3-Dimethylpiperidin-4-one hydrochloride represents an important building block in modern chemical synthesis, particularly for pharmaceutical applications. Its unique structural features and synthetic versatility continue to make it valuable across various research domains. As the chemical industry evolves, compounds like 3,3-Dimethylpiperidin-4-one HCl will likely play increasingly important roles in developing innovative solutions for healthcare and material science challenges.

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