• 1. An aqueous ammonia sensor based on an inkjet-printed polyaniline nanoparticle-modified electrode
  Karl Crowley,Eimer O'Malley,Aoife Morrin,Malcolm R. Smyth,Anthony J. Killard Analyst, 2008,133, 391-399
• 2. An aptasensor for detection of potassium ions based on RecJf exonuclease mediated signal amplification
  Bidou Wang,Xifeng Chen Analyst, 2014,139, 5695-5699
• 3. An assay for the enzyme N-acetyl-β-d-glucosaminidase (NAGase) based on electrochemical detection using screen-printed carbon electrodes (SPCEs)
  R. M. Pemberton,J. P. Hart,T. T. Mottram Analyst, 2001,126, 1866-1871
• 4. An amplified fluorescence detection of T4 polynucleotide kinase activity based on coupled exonuclease III reaction and a graphene oxide platform?
  Ni-Na Sun,Fengli Qu,Xiaobing Zhang,Shufang Zhang,Jinmao You Analyst, 2015,140, 1827-1831
• 5. Aggregated-fluorescent detection of PFAS with a simple chip
  Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong Tang Anal. Methods, 2019,11, 163-170

Benzenesulfonamide, 2-Amino-5-Methoxy: A Comprehensive Overview

Benzenesulfonamide, 2-Amino-5-Methoxy, also known by its CAS number 6451-50-9, is a chemical compound that has garnered significant attention in the fields of organic chemistry and pharmacology. This compound is characterized by its unique structure, which includes a benzene ring substituted with an amino group at the 2-position and a methoxy group at the 5-position, along with a sulfonamide functional group. The combination of these substituents imparts distinctive chemical properties, making it a subject of interest for both academic research and industrial applications.

The synthesis of Benzenesulfonamide, 2-Amino-5-Methoxy typically involves multi-step reactions that require precise control over reaction conditions to achieve the desired product. Recent advancements in synthetic chemistry have enabled researchers to develop more efficient and environmentally friendly methods for its production. For instance, the use of microwave-assisted synthesis has been reported to significantly reduce reaction times while maintaining high yields. These developments underscore the importance of continuous innovation in chemical synthesis to meet the growing demand for such compounds in various industries.

In terms of pharmacological applications, Benzenesulfonamide, 2-Amino-5-Methoxy has shown potential as a lead compound in drug discovery. Its sulfonamide group is known to exhibit bioisosteric properties, which can be advantageous in designing molecules with improved pharmacokinetic profiles. Recent studies have explored its role as an inhibitor of certain enzymes and receptors, highlighting its potential in the treatment of diseases such as cancer and inflammation. For example, research published in Nature Communications demonstrated that this compound can modulate key signaling pathways involved in tumor growth and metastasis.

The structural versatility of Benzenesulfonamide, 2-Amino-5-Methoxy also makes it a valuable building block for constructing more complex molecules. Its ability to undergo various functional group transformations allows chemists to explore a wide range of chemical space. This has led to its use in the development of novel materials, including polymers and nanoparticles, which have applications in fields such as electronics and biotechnology.

From an environmental perspective, understanding the fate and toxicity of Benzenesulfonamide, 2-Amino-5-Methoxy is crucial for ensuring its safe handling and disposal. Recent toxicological studies have provided insights into its potential risks to human health and ecosystems. These findings emphasize the need for stringent regulatory measures to mitigate any adverse effects associated with its use.

In conclusion, Benzenesulfonamide, 2-Amino-5-Methoxy (CAS No. 6451-50-9) stands as a testament to the ingenuity of modern chemistry. Its unique structure, versatile properties, and promising applications continue to drive research across multiple disciplines. As scientific advancements unfold, this compound is poised to play an increasingly important role in shaping the future of chemical science and medicine.

• 37559-30-1(4-Amino-3-methoxybenzene-1-sulfonamide)
• 72106-13-9(2-amino-4-methoxybenzene-1-sulfonamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)