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  Mehmet Sevim,Serdar Bat?kan Kavukcu,Arma?an K?nal,Onur ?ahin,Hayati Türkmen Dalton Trans. 2020 49 16903
• 2. A study of diketopiperazines as electron-donor initiators in transition metal-free haloarene–arene coupling
  Florimond Cumine,Shengze Zhou,Tell Tuttle,John A. Murphy Org. Biomol. Chem. 2017 15 3324
• 3. Sequential palladium catalyzed coupling–cyclocondensation–coupling (C3) four-component synthesis of intensively blue luminescent biarylsubstituted pyrazoles
  Melanie Deni?en,Jan Nordmann,Julian Dziambor,Bernhard Mayer,Walter Frank,Thomas J. J. Müller RSC Adv. 2015 5 33838
• 4. Thiazolidinedione derivatives as novel GPR120 agonists for the treatment of type 2 diabetes
  Xuekun Wang,Guoxia Ji,Xinyu Han,Huiran Hao,Wenjing Liu,Qidi Xue,Qinghua Guo,Shiben Wang,Kang Lei,Yadi Liu RSC Adv. 2022 12 5732
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Biphenyls and derivatives
• Solvents and Organic Chemicals Organic Compounds Hydrocarbons

Introduction to CAS No. 644-08-6: 4-Phenyltoluene

CAS No. 644-08-6, commonly known as 4-Phenyltoluene, is a fascinating aromatic compound that has garnered significant attention in various scientific and industrial domains. This compound, classified under the broader category of toluenes, is characterized by its unique structure and versatile applications. In recent years, advancements in synthetic chemistry and materials science have further highlighted the potential of 4-Phenyltoluene in diverse fields, making it a subject of extensive research.

The molecular structure of CAS No. 644-08-6 consists of a toluene derivative with a phenyl group attached at the para position of the methylbenzene ring. This arrangement imparts distinctive electronic and steric properties to the molecule, influencing its reactivity and functionality. Researchers have explored the synthesis of 4-Phenyltoluene through various methods, including Friedel-Crafts alkylation and coupling reactions, each offering unique advantages in terms of yield and purity.

In terms of physical properties, CAS No. 644-08-6 exhibits a melting point of approximately -5°C and a boiling point around 175°C, making it suitable for applications that require stability over a wide temperature range. Its solubility in organic solvents and limited solubility in water further enhance its utility in organic synthesis and formulation development.

The chemical stability of CAS No. 644-08-6 has been a focal point in recent studies, particularly in relation to its resistance to oxidation and photodegradation. Scientists have reported that the presence of the phenyl group at the para position significantly influences the compound's stability, making it a preferred choice in industries where long-term durability is essential.

CAS No. 644-08-6 finds extensive application in the field of materials science, particularly in the development of advanced polymers and composites. Its ability to act as a precursor for synthesizing high-performance materials has been widely documented in recent research papers. For instance, studies published in prominent journals such as Nature Materials and Advanced Materials highlight the role of 4-Phenyltoluene derivatives in creating lightweight yet robust polymer matrices for aerospace applications.

In addition to its role in materials science, CAS No. 644-08-6 has also emerged as a valuable compound in pharmaceutical research. Its structural similarity to certain bioactive molecules has led to its use as an intermediate in drug discovery processes. Recent breakthroughs include its application as a building block for developing potential anticancer agents, where its unique electronic properties facilitate interactions with target proteins.

The environmental impact of synthesizing and utilizing CAS No. 644-08-6 has also come under scrutiny in recent years. Researchers are actively exploring greener synthesis methods that minimize waste generation and reduce energy consumption during production processes.

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In conclusion,
CAS No.
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As technology advances,
we can expect even more innovative uses for this remarkable aromatic compound.

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