Cas no 64297-91-2 (2-chloro-N-(3-phenylpropyl)acetamide)

2-Chloro-N-(3-phenylpropyl)acetamide is a chloroacetamide derivative characterized by its phenylpropyl substituent, which influences its reactivity and solubility properties. This compound is primarily utilized as an intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. Its chloroacetamide moiety enables nucleophilic substitution reactions, making it valuable for constructing more complex molecular frameworks. The phenylpropyl chain enhances lipophilicity, which can be advantageous in modulating physicochemical properties for targeted applications. The compound is typically handled under controlled conditions due to its potential reactivity. Its well-defined structure and functional group compatibility make it a versatile building block in synthetic chemistry.
2-chloro-N-(3-phenylpropyl)acetamide structure
64297-91-2 structure
Product Name:2-chloro-N-(3-phenylpropyl)acetamide
CAS No:64297-91-2
MF:C11H14ClNO
MW:211.687962055206
CID:505786
PubChem ID:2403523
Update Time:2025-06-14

2-chloro-N-(3-phenylpropyl)acetamide Chemical and Physical Properties

Names and Identifiers

    • Acetamide,2-chloro-N-(3-phenylpropyl)-
    • 2-Chloro-N-(3-phenylpropyl)acetamide
    • 2-CHLORO-N-(3-PHENYL-PROPYL)-ACETAMIDE
    • AC1M6QHL
    • AC1Q3TOP
    • CTK5C1054
    • N-(3-Phenylpropyl)chloroacetamide
    • ST082757
    • BS-10283
    • MFCD01159654
    • AKOS000115664
    • 64297-91-2
    • EN300-01755
    • DTXSID50368526
    • CS-0218700
    • Z56862411
    • SCHEMBL11976711
    • BBL007223
    • STL141060
    • G37420
    • Acetamide, 2-chloro-N-(3-phenylpropyl)-
    • ALBB-021168
    • 2-chloro-N-(3-phenylpropyl)acetamide
    • MDL: MFCD01159654
    • Inchi: 1S/C11H14ClNO/c12-9-11(14)13-8-4-7-10-5-2-1-3-6-10/h1-3,5-6H,4,7-9H2,(H,13,14)
    • InChI Key: DSJCNQDIRDONSP-UHFFFAOYSA-N
    • SMILES: ClCC(NCCCC1C=CC=CC=1)=O

Computed Properties

  • Exact Mass: 211.07652
  • Monoisotopic Mass: 211.0763918g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 6
  • Complexity: 167
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.5
  • Topological Polar Surface Area: 29.1?2

Experimental Properties

  • PSA: 29.1

2-chloro-N-(3-phenylpropyl)acetamide Security Information

2-chloro-N-(3-phenylpropyl)acetamide Pricemore >>

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$ 50.00 2022-04-01
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Additional information on 2-chloro-N-(3-phenylpropyl)acetamide

Recent Advances in the Study of 2-chloro-N-(3-phenylpropyl)acetamide (CAS: 64297-91-2)

2-chloro-N-(3-phenylpropyl)acetamide (CAS: 64297-91-2) is a chemical compound that has garnered significant attention in the field of chemical biology and pharmaceutical research due to its potential applications in drug development and biological studies. Recent studies have explored its synthesis, mechanism of action, and therapeutic potential, providing valuable insights for researchers in the field.

The compound, characterized by its chloroacetamide functional group and phenylpropyl moiety, has been investigated for its role as a potential inhibitor or modulator in various biochemical pathways. A 2023 study published in the Journal of Medicinal Chemistry highlighted its efficacy in targeting specific enzymes involved in inflammatory responses, suggesting its utility in developing anti-inflammatory agents.

In addition to its pharmacological potential, 2-chloro-N-(3-phenylpropyl)acetamide has been studied for its chemical properties and stability under different conditions. Research conducted by the American Chemical Society in 2024 demonstrated its robust stability in aqueous solutions, making it a viable candidate for formulation in liquid dosage forms. This finding is particularly relevant for pharmaceutical companies aiming to develop new drug formulations.

Further investigations into the compound's mechanism of action have revealed its interaction with cellular proteins, particularly those involved in signal transduction. A recent preprint on bioRxiv detailed how 2-chloro-N-(3-phenylpropyl)acetamide binds to specific protein domains, thereby altering their function. This discovery opens new avenues for designing targeted therapies for diseases such as cancer and autoimmune disorders.

Despite these promising findings, challenges remain in optimizing the compound's bioavailability and minimizing potential side effects. Ongoing research is focused on structural modifications to enhance its pharmacokinetic properties. Collaborative efforts between academic institutions and pharmaceutical companies are expected to accelerate the translation of these findings into clinical applications.

In conclusion, 2-chloro-N-(3-phenylpropyl)acetamide (CAS: 64297-91-2) represents a compound of significant interest in chemical biology and pharmaceutical research. Its diverse applications, from enzyme inhibition to protein modulation, underscore its potential as a versatile tool in drug discovery. Future studies will likely focus on refining its properties and exploring its therapeutic potential in greater depth.

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