Cas no 637036-71-6 (4-(2,6-dimethylphenyl)piperidine)
4-(2,6-Dimethylphenyl)piperidine is a substituted piperidine derivative featuring a 2,6-dimethylphenyl group at the 4-position. This structural motif imparts steric and electronic properties that make it a valuable intermediate in pharmaceutical and agrochemical synthesis. The compound's rigid aromatic substitution enhances stability while the piperidine ring provides versatility for further functionalization. Its well-defined molecular structure ensures consistent reactivity in nucleophilic and electrophilic transformations. The 2,6-dimethyl substitution pattern on the phenyl ring offers controlled steric hindrance, influencing regioselectivity in downstream reactions. This compound is particularly useful in the development of bioactive molecules, where its balanced lipophilicity and conformational constraints contribute to optimized pharmacokinetic profiles.
637036-71-6 structure
Product Name:4-(2,6-dimethylphenyl)piperidine
CAS No:637036-71-6
MF:C13H19N
MW:189.29666352272
CID:425911
PubChem ID:21936982
Update Time:2025-06-07
4-(2,6-dimethylphenyl)piperidine Chemical and Physical Properties
Names and Identifiers
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- Piperidine, 4-(2,6-dimethylphenyl)-
- 4-(2,6-dimethylphenyl)piperidine
-
- Inchi: 1S/C13H19N/c1-10-4-3-5-11(2)13(10)12-6-8-14-9-7-12/h3-5,12,14H,6-9H2,1-2H3
- InChI Key: DTKWOMMTLVZDGC-UHFFFAOYSA-N
- SMILES: N1CCC(C2=C(C)C=CC=C2C)CC1
Computed Properties
- Exact Mass: 189.15187
Experimental Properties
- Density: 0.950±0.06 g/cm3(Predicted)
- Boiling Point: 302.4±31.0 °C(Predicted)
- PSA: 12.03
- pka: 10.21±0.10(Predicted)
4-(2,6-dimethylphenyl)piperidine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-1171552-0.05g |
4-(2,6-dimethylphenyl)piperidine |
637036-71-6 | 0.05g |
$1091.0 | 2023-06-08 | ||
| Enamine | EN300-1171552-0.1g |
4-(2,6-dimethylphenyl)piperidine |
637036-71-6 | 0.1g |
$1144.0 | 2023-06-08 | ||
| Enamine | EN300-1171552-0.25g |
4-(2,6-dimethylphenyl)piperidine |
637036-71-6 | 0.25g |
$1196.0 | 2023-06-08 | ||
| Enamine | EN300-1171552-0.5g |
4-(2,6-dimethylphenyl)piperidine |
637036-71-6 | 0.5g |
$1247.0 | 2023-06-08 | ||
| Enamine | EN300-1171552-1.0g |
4-(2,6-dimethylphenyl)piperidine |
637036-71-6 | 1g |
$1299.0 | 2023-06-08 | ||
| Enamine | EN300-1171552-2.5g |
4-(2,6-dimethylphenyl)piperidine |
637036-71-6 | 2.5g |
$2548.0 | 2023-06-08 | ||
| Enamine | EN300-1171552-5.0g |
4-(2,6-dimethylphenyl)piperidine |
637036-71-6 | 5g |
$3770.0 | 2023-06-08 | ||
| Enamine | EN300-1171552-10.0g |
4-(2,6-dimethylphenyl)piperidine |
637036-71-6 | 10g |
$5590.0 | 2023-06-08 | ||
| Enamine | EN300-1171552-50mg |
4-(2,6-dimethylphenyl)piperidine |
637036-71-6 | 50mg |
$647.0 | 2023-10-03 | ||
| Enamine | EN300-1171552-100mg |
4-(2,6-dimethylphenyl)piperidine |
637036-71-6 | 100mg |
$678.0 | 2023-10-03 |
4-(2,6-dimethylphenyl)piperidine Related Literature
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J. M. Granadino-Roldán,M. Fernández-Gómez,A. Navarro,T. Pe?a Ruiz,U. A. Jayasooriya Phys. Chem. Chem. Phys., 2004,6, 1133-1143
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Kathrin Kutlescha,Rhett Kempe New J. Chem., 2010,34, 1954-1960
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Christian K. Rank,Alexander W. Jones,Tatjana Wall,Patrick Di Martino-Fumo,Sarah Schr?ck,Markus Gerhards,Frederic W. Patureau Chem. Commun., 2019,55, 13749-13752
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