Cas no 63604-94-4 (2-Bromo-5-methoxyphenol)

2-Bromo-5-methoxyphenol is a brominated aromatic compound featuring a methoxy substituent at the 5-position of the phenol ring. This structure imparts unique reactivity, making it a valuable intermediate in organic synthesis, particularly in pharmaceutical and agrochemical applications. Its bromine moiety allows for further functionalization via cross-coupling reactions, while the methoxy group enhances electron density, influencing regioselectivity in electrophilic substitutions. The compound exhibits moderate stability under standard conditions, facilitating handling in laboratory settings. Its distinct substitution pattern is advantageous for constructing complex molecular architectures, including heterocycles and bioactive derivatives. Suitable for use under inert atmospheres, it is typically supplied in high purity to ensure consistent performance in synthetic workflows.
2-Bromo-5-methoxyphenol structure
2-Bromo-5-methoxyphenol structure
Product Name:2-Bromo-5-methoxyphenol
CAS No:63604-94-4
MF:C7H7BrO2
MW:203.033281564713
MDL:MFCD03428523
CID:58062
PubChem ID:13493839
Update Time:2025-11-02

2-Bromo-5-methoxyphenol Chemical and Physical Properties

Names and Identifiers

    • 2-Bromo-5-methoxyphenol
    • 4-Bromo-3-hydroxyanisole
    • Phenol, 2-bromo-5- methoxy-
    • 2-bromo-5-methoxy-phenol
    • PHENOL, 2-BROMO-5-METHOXY-
    • 1-bromo-2-hydroxy-4-methoxy benzene
    • PubChem13262
    • 4-bromo-3-hydroxyanisol
    • 2-bromo -5-methoxyphenol
    • 2-Bromo-5-methoxy phenol
    • 2-bromanyl-5-methoxy-phenol
    • KSC497Q1J
    • AMBZ0261
    • KHGMUWBYGFWGCZ-UHFFFAOYSA-N
    • 1-Bromo-2-hydroxy-4methoxybenzene
    • BCP26900
    • 1-Bromo-2-hydroxy-4-methoxybenzene
    • RW3350
    • A8756
    • BCP9000097
    • EN300-177992
    • FT-0648043
    • SCHEMBL154623
    • SY019932
    • DTXSID60542153
    • FS-3063
    • 63604-94-4
    • AKOS005259403
    • AC-16336
    • A834438
    • MB02872
    • CS-W003079
    • AM20040925
    • MFCD03428523
    • DTXCID30492939
    • DB-010042
    • MDL: MFCD03428523
    • Inchi: 1S/C7H7BrO2/c1-10-5-2-3-6(8)7(9)4-5/h2-4,9H,1H3
    • InChI Key: KHGMUWBYGFWGCZ-UHFFFAOYSA-N
    • SMILES: BrC1C=CC(=CC=1O)OC

Computed Properties

  • Exact Mass: 201.96300
  • Monoisotopic Mass: 201.96294 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 108
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Molecular Weight: 203.03
  • XLogP3: 2.5
  • Topological Polar Surface Area: 29.5

Experimental Properties

  • Color/Form: No data avaiable
  • Density: 1.6±0.1 g/cm3
  • Melting Point: No data available
  • Boiling Point: 253.3°C at 760 mmHg
  • Flash Point: 107.0±21.8 °C
  • Refractive Index: 1.578
  • PSA: 29.46000
  • LogP: 2.16330
  • Vapor Pressure: No data available

2-Bromo-5-methoxyphenol Security Information

2-Bromo-5-methoxyphenol Customs Data

  • HS CODE:2909500000
  • Customs Data:

    China Customs Code:

    2909500000

    Overview:

    2909500000. Ether phenol\Ether alcohol phenol and its halogenation\sulfonation\Nitrosative or nitrosative derivatives. VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:nothing. MFN tariff:5.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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2-Bromo-5-methoxyphenol Production Method

2-Bromo-5-methoxyphenol Related Literature

Additional information on 2-Bromo-5-methoxyphenol

Exploring the Properties and Applications of 2-Bromo-5-methoxyphenol (CAS No. 63604-94-4)

2-Bromo-5-methoxyphenol (CAS No. 63604-94-4) is a versatile organic compound that has garnered significant attention in various industries due to its unique chemical properties and wide-ranging applications. This aromatic compound, featuring a bromine substituent and a methoxy group on a phenol ring, serves as a crucial intermediate in pharmaceuticals, agrochemicals, and material science. Its molecular formula, C7H7BrO2, and distinct structural features make it a valuable building block in synthetic chemistry.

One of the most frequently asked questions about 2-Bromo-5-methoxyphenol is its role in drug development. Researchers often search for "2-Bromo-5-methoxyphenol uses in medicine" or "CAS 63604-94-4 pharmaceutical applications," highlighting the growing interest in its potential therapeutic benefits. Recent studies suggest that this compound may serve as a precursor in the synthesis of bioactive molecules, particularly those targeting inflammatory pathways. Its ability to undergo various chemical transformations, such as coupling reactions and substitutions, makes it indispensable in medicinal chemistry.

In the agrochemical sector, 2-Bromo-5-methoxyphenol is explored for its potential as a key intermediate in the production of crop protection agents. Searches like "2-Bromo-5-methoxyphenol in pesticides" reflect the industry's demand for eco-friendly and efficient solutions. The compound's structural flexibility allows for the development of novel formulations that address emerging challenges in agriculture, such as pest resistance and environmental sustainability.

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From a chemical perspective, 2-Bromo-5-methoxyphenol exhibits notable stability under standard conditions, making it suitable for various industrial processes. Its solubility in organic solvents and moderate reactivity profile facilitate its use in multi-step synthetic routes. Safety data sheets often highlight its handling precautions, emphasizing the importance of proper storage and ventilation to ensure safe laboratory practices.

The market for 2-Bromo-5-methoxyphenol continues to expand, driven by increasing demand from end-use industries. Trends such as "2-Bromo-5-methoxyphenol market growth 2024" and "CAS 63604-94-4 suppliers" reflect the compound's commercial significance. Manufacturers are investing in scalable production methods to meet global requirements while maintaining high purity standards.

Environmental considerations are another hot topic surrounding 2-Bromo-5-methoxyphenol. Researchers and regulatory bodies are investigating its biodegradability and ecological impact, addressing concerns raised by searches like "2-Bromo-5-methoxyphenol environmental safety." Sustainable synthesis routes and waste management strategies are being developed to minimize its footprint.

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Future research directions for 2-Bromo-5-methoxyphenol include exploring its potential in nanotechnology and green chemistry initiatives. Emerging queries like "2-Bromo-5-methoxyphenol in nano-applications" signal new opportunities for innovation. Scientists are investigating its use in catalytic systems and as a building block for smart materials.

In conclusion, 2-Bromo-5-methoxyphenol (CAS No. 63604-94-4) represents a multifaceted compound with significant scientific and industrial value. Its applications span multiple sectors, from healthcare to advanced materials, making it a subject of ongoing research and commercial interest. As technology advances, this compound will likely play an increasingly important role in addressing global challenges through innovative chemical solutions.

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