Cas no 63283-36-3 (Calcifediol monohydrate)
Calcifediol monohydrate Chemical and Physical Properties
Names and Identifiers
-
- CALCIDIOL
- CALCIFEDIOL MONOHYDRATE
- 25-OH-D3
- 25-HYDROXYVITAMIN D3
- 25-hydroxyvitamin d3 monohydrate
- 25-hydroxycholecalciferol monohydrate
- (5z,7e)-9,10-secocholesta-5,7,10(19)-triene-3b,25-diol monohydrate
- CALCIFEDIOL 1-HYDRATE
- 9,10-Secocholesta-5,7,10(19)-triene-3,25-diol, monohydrate, (3.beta.,5Z,7E)-
- 25-Hydroxycholecalciferol
- calcifediol
- Vitamin D3, 25-Hydroxy-
- 25-Hydroxy-vitamin D3 monohydrate
- (3beta,5Z,7E)-9,10-secocholestan-5,7,10(19)-triene-3,25-diol
- 25-OH-Vitamin D3
- (S,Z)-3-((E)-2-((1R,3aS,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyldihydro-1H-inden-4(2H,5H,6H,7H,7aH)-ylidene)ethylidene)-4-methylenecyclohexanol
- (1S)-3-[2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-h
- (1S)-3-[2-[(1R,3As,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-i
- Calcifediol monohydrate
-
- MDL： MFCD00867077
- Inchi： 1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/t20-,23+,24-,25+,27-/m1/s1
- InChI Key： JWUBBDSIWDLEOM-DLBXBJKMSA-N
- SMILES： O([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])C(=C([H])C([H])=C3C(=C([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C3([H])[H])O[H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
Computed Properties
- Exact Mass: 400.33400
- Monoisotopic Mass: 418.34469533 g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 29
- Rotatable Bond Count: 6
- Complexity: 655
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 4
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 2
- Undefined Bond Stereocenter Count: 0
- Molecular Weight: 418.7
- Topological Polar Surface Area: 40.5
Experimental Properties
- Color/Form: Powder
- Flash Point: Fahrenheit: 57.2 ° f
Celsius: 14 ° c - PSA: 40.46000
- LogP: 6.73390
- Color/Form: 100?μg/mL in ethanol
Calcifediol monohydrate Security Information
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Symbol:
- Prompt：dangerous
- Signal Word：Danger
- Hazard Statement： H300+H310+H330-H372-H413
- Warning Statement： P260-P262-P264-P270-P271-P273-P280-P284-P301+P310+P330-P302+P352+P310+P361+P364-P304+P340+P310-P314-P403+P233-P405-P501
- Hazardous Material transportation number：UN 2811 6.1/PG 2
- WGK Germany：3
- Hazard Category Code： 24/25-26-48/25
- Safety Instruction： 28-36/37-45
- FLUKA BRAND F CODES：8-10-19
-
Hazardous Material Identification：
- HazardClass：6.1
- PackingGroup：II
- Storage Condition：4°C, protect from light, stored under nitrogen
- Risk Phrases：R28
Calcifediol monohydrate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | H811310-5mg |
25-Hydroxyvitamin D3 monohydrate |
63283-36-3 | 98% | 5mg |
￥786.00 | 2022-01-14 | |
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | H-083-1ML |
Calcifediol monohydrate |
63283-36-3 | 1ml |
￥2346.81 | 2023-11-01 | ||
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | PHR2359-100MG |
Calcifediol monohydrate |
63283-36-3 | 100mg |
￥8506.19 | 2025-01-10 | ||
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 1086108-75MG |
Calcifediol monohydrate |
63283-36-3 | 75mg |
￥9344.9 | 2023-09-09 | ||
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | C0166000-3EA |
Calcifediol monohydrate |
63283-36-3 | European Pharmacopoeia (EP) Reference Standard | 3EA |
￥2361.7 | 2022-02-23 | |
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 17938-1MG |
Calcifediol monohydrate |
63283-36-3 | 1mg |
￥4554.21 | 2023-10-03 | ||
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | C3537-50MG |
Calcifediol Monohydrate |
63283-36-3 | >98.0%(HPLC) | 50mg |
￥2490.00 | 2024-04-16 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajci17682-5mg |
Calcifediol monohydrate |
63283-36-3 | 98% | 5mg |
￥756.00 | 2023-09-09 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajci17682-25mg |
Calcifediol monohydrate |
63283-36-3 | 98% | 25mg |
￥2552.00 | 2023-09-09 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajci17682-100mg |
Calcifediol monohydrate |
63283-36-3 | 98% | 100mg |
￥7884.00 | 2023-09-09 |
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Calcifediol monohydrate Related Literature
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Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
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Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
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Goonay Yousefalizadeh,Shideh Ahmadi,Nicholas J. Mosey,Kevin G. Stamplecoskie Nanoscale, 2021,13, 242-252
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Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
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Max Attwood,Hiroki Akutsu,Lee Martin,Toby J. Blundell,Pierre Le Maguere,Scott S. Turner Dalton Trans., 2021,50, 11843-11851
Additional information on Calcifediol monohydrate
Comprehensive Overview of Calcifediol Monohydrate (CAS No. 63283-36-3): Benefits, Applications, and Research Insights
Calcifediol monohydrate (CAS No. 63283-36-3), also known as 25-hydroxyvitamin D3 monohydrate, is a biologically active metabolite of vitamin D3. This compound plays a pivotal role in calcium homeostasis and bone health, making it a subject of significant interest in medical and nutritional research. With the growing awareness of vitamin D deficiency and its global health implications, Calcifediol monohydrate has emerged as a critical supplement and therapeutic agent.
The primary function of Calcifediol monohydrate is to serve as a precursor to calcitriol (1,25-dihydroxyvitamin D3), the most active form of vitamin D. Unlike cholecalciferol (vitamin D3), which requires hepatic hydroxylation, 25-hydroxyvitamin D3 is directly converted in the kidneys, offering a more efficient pathway for addressing vitamin D insufficiency. This efficiency has led to its widespread use in clinical settings, particularly for patients with chronic kidney disease (CKD) or malabsorption syndromes.
Recent studies highlight the broader implications of Calcifediol monohydrate beyond bone health. Research suggests its potential role in modulating immune function, reducing inflammation, and even supporting cardiovascular health. These findings align with current user searches such as "vitamin D and immune support" and "Calcifediol vs. cholecalciferol," reflecting public interest in optimized vitamin D supplementation strategies.
From a pharmaceutical perspective, Calcifediol monohydrate is valued for its stability and bioavailability. The monohydrate form ensures improved solubility, which is critical for formulation development. Industries prioritize this compound for nutraceutical applications, especially in regions with limited sunlight exposure, where vitamin D deficiency is prevalent. Searches like "best bioavailable vitamin D form" underscore the demand for effective solutions.
Quality control and regulatory compliance are paramount for Calcifediol monohydrate manufacturers. Analytical techniques such as HPLC and NMR are employed to verify purity (typically ≥98%), addressing concerns like "how to identify pure Calcifediol." The compound’s CAS No. 63283-36-3 serves as a unique identifier for procurement and safety documentation, ensuring transparency in supply chains.
In conclusion, Calcifediol monohydrate (CAS No. 63283-36-3) represents a cornerstone in modern vitamin D therapy. Its multifaceted benefits, coupled with rising health consciousness, position it as a key player in addressing global nutritional challenges. Continued research and innovation will further unlock its potential, meeting the evolving needs of healthcare professionals and consumers alike.
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