• 1. Aggregation-induced chiroptical generation and photoinduced switching of achiral azobenzene-alt-fluorene copolymer endowed with left- and right-handed helical polysilanes?
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• 2. Aggregation of biologically important peptides and proteins: inhibition or acceleration depending on protein and metal ion concentrations
  Benjamin Gabriel Poulson,Kacper Szczepski,Joanna Izabela Lachowicz,Lukasz Jaremko,Abdul-Hamid Emwas,Mariusz Jaremko RSC Adv., 2020,10, 215-227
• 3. An alumina stabilized graphene oxide wrapped SnO2 hollow sphere LIB anode with improved lithium storage?
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• 4. An algal process treatment combined with the Fenton reaction for high concentrations of amoxicillin and cefradine
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• 5. An approach for correlating the structural and electrical properties of Zr4+-modified SrBi4Ti4O15/SBT ceramic
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzenesulfonamides

Comprehensive Overview of 4-Chloro-N-ethylbenzene-1-sulfonamide (CAS No. 6318-34-9): Properties, Applications, and Industry Insights

4-Chloro-N-ethylbenzene-1-sulfonamide (CAS No. 6318-34-9) is a specialized sulfonamide derivative with a molecular formula of C₈H₁₀ClNO₂S. This compound has garnered attention in pharmaceutical and agrochemical research due to its unique structural properties and potential as an intermediate in synthetic chemistry. With a molecular weight of 219.69 g/mol, it features a chlorobenzene core linked to an ethylsulfonamide group, offering reactivity for further functionalization.

In recent years, the demand for sulfonamide-based compounds like 4-chloro-N-ethylbenzene-1-sulfonamide has surged, driven by their versatility in drug discovery. Researchers frequently search for "sulfonamide applications in medicine" or "chlorobenzene derivatives in synthesis," reflecting its relevance in developing antimicrobial and anti-inflammatory agents. The compound’s electrophilic aromatic substitution sites make it valuable for creating targeted molecules, aligning with trends in precision chemistry.

From a technical perspective, 6318-34-9 exhibits moderate solubility in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol, while remaining stable under standard storage conditions. Its melting point ranges between 85–90°C, and its purity (>98%) is critical for laboratory use. Analytical techniques like HPLC and NMR spectroscopy are commonly employed to verify its quality, addressing frequent queries like "how to analyze sulfonamide purity."

Environmental and regulatory considerations are also pivotal. While not classified as hazardous, proper handling protocols for chlorinated compounds are emphasized in industrial settings. Searches for "green synthesis of sulfonamides" highlight the growing focus on sustainable production methods. Innovations in catalytic processes aim to reduce waste generation during the manufacture of intermediates like 4-chloro-N-ethylbenzene-1-sulfonamide.

The compound’s role extends to material science, where its sulfonyl group facilitates polymer modification. Queries such as "sulfonamides in polymer chemistry" underscore its utility in enhancing thermal stability or solubility of advanced materials. Additionally, patents referencing CAS 6318-34-9 often involve photoactive materials or organic electronics, tapping into the booming interest in renewable energy technologies.

In summary, 4-chloro-N-ethylbenzene-1-sulfonamide represents a multifaceted chemical building block. Its integration into high-value applications—from life sciences to industrial materials—positions it as a compound of enduring scientific and commercial interest. Ongoing research into its structure-activity relationships and process optimization will likely expand its footprint across interdisciplinary fields.

• 218920-93-5(Benzenesulfonamide, 4-chloro-N-(cyanomethyl)-)
• 151389-59-2(N1-(2-Bromoethyl)-4-chlorobenzene-1-sulfonamide)
• 83019-90-3(N-(2-Aminoethyl)-4-chlorobenzenesulfonamide)
• 88523-48-2(Benzenesulfonamide, 4-chloro-N-(2-hydroxyethyl)-, sodium salt (1:1))
• 29024-82-6(Benzenesulfonamide,4-chloro-N-(2-methylpropyl)-)
• 28860-19-7(Benzenesulfonamide,4-chloro-N-(1-methylethyl)-)
• 6419-69-8(4-Chloro-N-(2-hydroxyethyl)benzenesulfonamide)
• 6419-73-4(Benzenesulfonamide,N-butyl-4-chloro-)
• 28860-18-6(4-chloro-N-propylbenzene-1-sulfonamide)
• 6326-17-6(3,4-dichloro-N-ethylbenzene-1-sulfonamide)