Cas no 630384-36-0 (CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,MEHTYL ESTER)

Cyclopropanecarboxylic acid, 1-(4-iodophenyl)-, methyl ester is a cyclopropane-derived ester compound featuring an iodophenyl substituent. Its unique structure, combining a cyclopropane ring with an aromatic iodine group, makes it a valuable intermediate in organic synthesis and pharmaceutical research. The presence of the iodine atom enhances its utility in cross-coupling reactions, such as Suzuki or Heck couplings, enabling the construction of complex molecular frameworks. The methyl ester group improves solubility and reactivity in various synthetic applications. This compound is particularly useful in medicinal chemistry for the development of bioactive molecules, owing to its stability and functional versatility. Proper handling and storage are recommended due to its sensitivity to light and moisture.
CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,MEHTYL ESTER structure
630384-36-0 structure
Product Name:CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,MEHTYL ESTER
CAS No:630384-36-0
MF:C11H11IO2
MW:302.108315706253
MDL:MFCD15523646
CID:1011748
PubChem ID:58841088
Update Time:2025-11-02

CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,MEHTYL ESTER Chemical and Physical Properties

Names and Identifiers

    • CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,MEHTYL ESTER
    • SCHEMBL5641709
    • MFCD15523646
    • methyl 1-(4-iodophenyl)cyclopropanecarboxylate
    • DB-109050
    • AKOS030631932
    • DS-20095
    • METHYL 1-(4-IODOPHENYL)CYCLOPROPANE-1-CARBOXYLATE
    • methyl1-(4-iodophenyl)cyclopropanecarboxylate
    • C11H11IO2
    • CS-0150911
    • 630384-36-0
    • MDL: MFCD15523646
    • Inchi: 1S/C11H11IO2/c1-14-10(13)11(6-7-11)8-2-4-9(12)5-3-8/h2-5H,6-7H2,1H3
    • InChI Key: AFNUSZPFMBSKAE-UHFFFAOYSA-N
    • SMILES: IC1C=CC(=CC=1)C1(C(=O)OC)CC1

Computed Properties

  • Exact Mass: 301.97993
  • Monoisotopic Mass: 301.98038g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 3
  • Complexity: 227
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.7
  • Topological Polar Surface Area: 26.3?2

Experimental Properties

  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 308.7±35.0 °C at 760 mmHg
  • Flash Point: 140.5±25.9 °C
  • PSA: 26.3
  • Vapor Pressure: 0.0±0.7 mmHg at 25°C

CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,MEHTYL ESTER Security Information

CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,MEHTYL ESTER Pricemore >>

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abcr
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Additional information on CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,MEHTYL ESTER

Comprehensive Guide to CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,METHYL ESTER (CAS No: 630384-36-0)

CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,METHYL ESTER (CAS No: 630384-36-0) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This ester derivative, featuring a cyclopropane ring and an iodophenyl group, is widely studied for its unique structural properties and potential applications in drug development. Researchers and industry professionals frequently search for this compound due to its relevance in medicinal chemistry and organic synthesis.

The molecular structure of CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,METHYL ESTER combines a cyclopropane moiety with an aromatic iodophenyl substituent, making it a valuable intermediate in synthesizing bioactive molecules. Its CAS No: 630384-36-0 is often referenced in patent literature and scientific databases, highlighting its importance in modern chemistry. The presence of the iodine atom enhances its utility in cross-coupling reactions, a hot topic in catalysis and green chemistry.

One of the key reasons CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,METHYL ESTER is trending is its potential role in developing small-molecule therapeutics. With the growing demand for targeted drug delivery systems, compounds like this are being explored for their ability to modulate biological pathways. Searches related to drug discovery intermediates and pharmaceutical building blocks often include this compound, reflecting its relevance in cutting-edge research.

In addition to pharmaceutical applications, CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,METHYL ESTER is also studied for its physicochemical properties. Researchers are particularly interested in its stability, solubility, and reactivity under various conditions. These characteristics are crucial for optimizing synthetic routes and improving yields, topics frequently discussed in process chemistry forums.

The synthesis of CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,METHYL ESTER typically involves multi-step organic reactions, including esterification and cyclopropanation. Advanced techniques such as microwave-assisted synthesis and flow chemistry are being explored to enhance efficiency, aligning with the industry's shift toward sustainable chemistry practices.

Market trends indicate a rising demand for high-purity intermediates like CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,METHYL ESTER. Pharmaceutical companies and contract research organizations (CROs) are actively sourcing this compound for preclinical and clinical studies. The CAS No: 630384-36-0 is frequently listed in procurement databases, underscoring its commercial significance.

For researchers working on structure-activity relationships (SAR), CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,METHYL ESTER offers a versatile scaffold. Its iodophenyl group can be further functionalized, enabling the creation of diverse analogs. This flexibility is particularly valuable in fragment-based drug design, a rapidly evolving field in biotechnology.

Analytical characterization of CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,METHYL ESTER involves techniques such as NMR spectroscopy, mass spectrometry, and HPLC. These methods ensure the compound meets the stringent quality standards required for research and industrial use. Discussions around analytical method validation often reference such compounds, emphasizing their role in quality control.

In conclusion, CYCLOPROPANECARBOXYLIC ACID,1-(4-IODOPHENYL)-,METHYL ESTER (CAS No: 630384-36-0) is a compound of high interest in both academic and industrial settings. Its unique structure, combined with its potential applications in drug development and organic synthesis, makes it a focal point for ongoing research. As the scientific community continues to explore novel chemical entities, this compound is poised to remain a key player in advancing molecular innovation.

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