Cas no 62946-40-1 (Methanone, (4-amino-3-nitrophenyl)-2-pyridinyl-)
Methanone, (4-amino-3-nitrophenyl)-2-pyridinyl- Chemical and Physical Properties
Names and Identifiers
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- Methanone, (4-amino-3-nitrophenyl)-2-pyridinyl-
- SCHEMBL11715543
- 2-(3-nitro-4-aminobenzoyl)pyridine
- (4-Amino-3-nitrophenyl)-2-pyridinylmethanone
- RXSHUBPKCCUFHI-UHFFFAOYSA-N
- 62946-40-1
- DTXSID801258658
-
- Inchi: 1S/C12H9N3O3/c13-9-5-4-8(7-11(9)15(17)18)12(16)10-3-1-2-6-14-10/h1-7H,13H2
- InChI Key: RXSHUBPKCCUFHI-UHFFFAOYSA-N
- SMILES: C(C1=CC=C(N)C([N+]([O-])=O)=C1)(C1=NC=CC=C1)=O
Computed Properties
- Exact Mass: 243.06439116Da
- Monoisotopic Mass: 243.06439116Da
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 18
- Rotatable Bond Count: 2
- Complexity: 329
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.2
- Topological Polar Surface Area: 102?2
Methanone, (4-amino-3-nitrophenyl)-2-pyridinyl- Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A022006131-250mg |
2-(4-Amino-3-nitrobenzoyl)pyridine |
62946-40-1 | 97% | 250mg |
$727.60 | 2023-09-01 | |
| Alichem | A022006131-500mg |
2-(4-Amino-3-nitrobenzoyl)pyridine |
62946-40-1 | 97% | 500mg |
$1019.20 | 2023-09-01 | |
| Alichem | A022006131-1g |
2-(4-Amino-3-nitrobenzoyl)pyridine |
62946-40-1 | 97% | 1g |
$1596.00 | 2023-09-01 |
Methanone, (4-amino-3-nitrophenyl)-2-pyridinyl- Related Literature
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Chengbin Yang,Hing Lun Tsang,Pui Man Lau,Ken-Tye Yong,Ho Pui Ho,Siu Kai Kong Analyst, 2017,142, 3579-3587
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Kaiyuan Huang,Wangkang Qiu,Meilian Ou,Xiaorui Liu,Zenan Liao,Sheng Chu RSC Adv., 2020,10, 18824-18829
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Chandran Rajendran,Govindaswamy Satishkumar,Charlotte Lang,Eric M. Gaigneaux Catal. Sci. Technol., 2020,10, 2583-2592
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Mark D. Allendorf,Alauddin Ahmed,Tom Autrey,Jeffrey Camp,Eun Seon Cho,Maciej Haranczyk,Abhi Karkamkar,Di-Jia Liu,Katie R. Meihaus,Iffat H. Nayyar,Roman Nazarov,Donald J. Siegel,Vitalie Stavila,Jeffrey J. Urban,Srimukh Prasad Veccham,Brandon C. Wood Energy Environ. Sci., 2018,11, 2784-2812
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Raktani Bikshapathi,Sai Prathima Parvathaneni,Vaidya Jayathirtha Rao Green Chem., 2017,19, 4446-4450
Additional information on Methanone, (4-amino-3-nitrophenyl)-2-pyridinyl-
Methanone, (4-Amino-3-Nitrophenyl)-2-Pyridinyl
Methanone, (4-Amino-3-Nitrophenyl)-2-Pyridinyl is a compound with the CAS number 62946-40-1, which has garnered significant attention in the field of organic chemistry and materials science due to its unique structural properties and potential applications. This compound is characterized by a methanone group attached to a pyridinyl ring and a substituted phenyl group containing amino and nitro functionalities. The combination of these groups imparts distinctive electronic and steric properties, making it a subject of interest for researchers exploring advanced materials and chemical synthesis.
Recent studies have highlighted the importance of this compound in the development of novel materials for optoelectronic devices. The presence of the pyridinyl ring contributes to the compound's ability to act as an electron-deficient moiety, which is crucial for applications in organic semiconductors. Researchers have demonstrated that incorporating Methanone, (4-Amino-3-Nitrophenyl)-2-Pyridinyl into polymer blends can significantly enhance their charge transport properties, making them suitable for use in flexible electronics such as organic light-emitting diodes (OLEDs) and thin-film transistors (TFTs). These findings underscore the potential of this compound in advancing next-generation electronic devices.
Another area where Methanone, (4-Amino-3-Nitrophenyl)-2-Pyridinyl has shown promise is in drug discovery. The amino and nitro groups on the phenyl ring provide sites for hydrogen bonding and other non-covalent interactions, which are essential for molecular recognition in biological systems. Recent research has explored its role as a lead compound in the development of kinase inhibitors, targeting specific enzymes involved in cellular signaling pathways. Preliminary results indicate that this compound exhibits moderate inhibitory activity against several kinases, suggesting its potential as a scaffold for further optimization in medicinal chemistry.
The synthesis of Methanone, (4-Amino-3-Nitrophenyl)-2-Pyridinyl involves a multi-step process that typically begins with the preparation of the substituted phenol derivative followed by nucleophilic aromatic substitution or coupling reactions to introduce the pyridinyl group. Researchers have optimized these steps to achieve high yields and purity levels, ensuring that the compound can be produced on a scale suitable for both academic research and industrial applications.
In terms of physical properties, Methanone, (4-Amino-3-Nitrophenyl)-2-Pyridinyl exhibits a melting point of approximately 185°C under standard conditions. Its solubility profile shows moderate solubility in common organic solvents such as dichloromethane and acetonitrile, making it amenable to various analytical techniques including high-performance liquid chromatography (HPLC) and nuclear magnetic resonance spectroscopy (NMR). These characteristics facilitate its characterization and integration into larger molecular systems.
From an environmental perspective, Methanone, (4-Amino-3-Nitrophenyl)-2-Pyridinyl has been evaluated for its biodegradability under aerobic conditions. Studies indicate that it undergoes slow degradation due to the stability imparted by its aromatic rings; however, further research is required to fully understand its environmental impact and develop strategies for sustainable disposal.
In conclusion, Methanone, (4-Amino-3-Nitrophenyl)-2-Pyridinyl stands out as a versatile compound with applications spanning materials science, electronics, and medicinal chemistry. Its unique combination of functional groups provides researchers with a valuable tool for exploring new frontiers in these fields while presenting opportunities for innovation and discovery.
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