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• Solvents and Organic Chemicals Organic Compounds Organohalogen compounds Organobromides Organobromides
• Solvents and Organic Chemicals Organic Compounds Organohalogen compounds Organobromides
• Solvents and Organic Chemicals Organic Compounds Organic Halides

Chemical Profile of 1,6-Dibromohexane (CAS No: 629-03-8)

1,6-Dibromohexane, with the chemical formula C?H??Br?, is a brominated alkane that has garnered significant attention in the field of organic synthesis and material science. This compound, identified by its unique CAS number 629-03-8, serves as a versatile intermediate in the preparation of various functionalized molecules. Its molecular structure, featuring two bromine atoms attached to a hexane chain, makes it a valuable precursor for further chemical modifications, including cross-coupling reactions, polymerization processes, and the synthesis of pharmaceutical intermediates.

The utility of 1,6-Dibromohexane stems from its reactivity at the bromine substituents. These atoms can participate in nucleophilic substitution reactions, allowing chemists to introduce diverse functional groups into the molecule. Such transformations are pivotal in medicinal chemistry, where tailored molecular architectures are essential for achieving desired pharmacological properties. Recent advancements in synthetic methodologies have highlighted the role of 1,6-Dibromohexane in constructing complex scaffolds that mimic natural products and bioactive compounds.

In the realm of polymer science, 1,6-Dibromohexane has been explored as a monomer or crosslinking agent in the development of novel polymers. Its ability to form covalent bonds with other reactive species enables the creation of materials with tailored mechanical and thermal properties. For instance, researchers have utilized this compound to synthesize block copolymers that exhibit stimuli-responsive behaviors, which are relevant for applications in smart materials and drug delivery systems.

Recent studies have also demonstrated the potential of 1,6-Dibromohexane in catalytic processes. The bromine atoms can act as anchors for transition metal catalysts, facilitating various organic transformations such as Heck coupling and Suzuki-Miyaura reactions. These reactions are cornerstone techniques in modern synthetic chemistry, enabling the efficient construction of carbon-carbon bonds. The incorporation of 1,6-Dibromohexane into these protocols has streamlined synthetic routes for complex molecules, including those with pharmaceutical relevance.

The pharmaceutical industry has shown particular interest in derivatives of 1,6-Dibromohexane due to their structural versatility. Researchers have employed this compound as a building block in the synthesis of kinase inhibitors, which are critical targets for treating various cancers and inflammatory diseases. By modifying the positions and types of substituents on the hexane backbone, scientists can fine-tune the binding affinity and selectivity of these inhibitors towards their biological targets. Such efforts align with ongoing trends in drug discovery aimed at developing more effective and personalized therapies.

Moreover, the agrochemical sector has leveraged 1,6-Dibromohexane in the development of novel pesticides and herbicides. Its reactivity allows for the introduction of bioactive moieties that disrupt essential metabolic pathways in pests while minimizing environmental impact. This aligns with global efforts to create sustainable agricultural practices that reduce reliance on traditional chemical formulations.

The industrial applications of 1,6-Dibromohexane extend beyond pharmaceuticals and agrochemicals. It is also used in the manufacture of specialty chemicals such as flame retardants and plasticizers. These materials enhance the safety and performance of consumer products by imparting desirable properties like heat resistance and flexibility. The demand for high-performance materials continues to drive innovation in brominated compounds like 1,6-Dibromohexane, underscoring its importance in industrial chemistry.

From an environmental perspective, the handling and disposal of 1,6-Dibromohexane must be conducted with care due to its potential reactivity and persistence under certain conditions. Regulatory agencies recommend adherence to best practices in chemical management to ensure safety and minimize ecological impact. Advances in green chemistry have prompted investigations into more sustainable synthetic routes for brominated compounds, including alternative methods for producing 1,6-Dibromohexane that reduce waste and energy consumption.

In conclusion,1,6-Dibromohexane (CAS No: 629-03-8) is a multifaceted compound with broad applications across multiple scientific disciplines. Its role as an intermediate in organic synthesis underscores its significance in drug development、material science，and industrial chemistry。 As research continues to uncover new methodologies for utilizing this compound，its relevance is expected to grow further，contributing to advancements that benefit society while maintaining environmental stewardship.

• 2159-17-3(1-Bromohexane-2,2,3,3,4,4,5,5,6,6,6-d11)
• 150017-88-2(1,10-Dibromodecane-d20)
• 14296-16-3(Eicosane, 1,20-dibromo-)
• 284474-47-1(1-Bromodecane-10,10,10-d3)
• 26746-34-9(Octane, bromo-)
• 187826-28-4(1-Bromooctadecane-d37)
• 130131-94-1(6-Bromohexane-d13)
• 2159-25-3(Dodecane-1,1-d2,1-bromo- (7CI,9CI))
• 284474-40-4(1-Bromohexadecane-16,16,16-d3)
• 284474-45-9(1-Bromotridecane-1,1,2,2-d4)