Cas no 627526-67-4 (BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)-)
BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)- Chemical and Physical Properties
Names and Identifiers
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- BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)-
- Boronic acid, B-(5-fluoro-2-naphthalenyl)-
- (5-fluoronaphthalen-2-yl)boronic acid
- SCHEMBL5778117
- 5-fluoronaphthalene-2-boronic acid
- VYASLJZCRSOQTQ-UHFFFAOYSA-N
- 627526-67-4
- 5-fluoro-naphthalene-2-boronic acid
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- Inchi: 1S/C10H8BFO2/c12-10-3-1-2-7-6-8(11(13)14)4-5-9(7)10/h1-6,13-14H
- InChI Key: VYASLJZCRSOQTQ-UHFFFAOYSA-N
- SMILES: B(C1=CC=C2C(=C1)C=CC=C2F)(O)O
Computed Properties
- Exact Mass: 190.0601378Da
- Monoisotopic Mass: 190.0601378Da
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 14
- Rotatable Bond Count: 1
- Complexity: 201
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 40.5?2
BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)- Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A249000077-1g |
5-Fluoronaphthalene-2-boronic acid |
627526-67-4 | 98% | 1g |
$1729.47 | 2023-09-01 |
BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)- Related Literature
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Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
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Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
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Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
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Martin R. Ward,Gary W. Copeland,Andrew J. Alexander Chem. Commun., 2010,46, 7634-7636
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Chao-Han Cheng,Wen-Zhen Wang,Shie-Ming Peng,I-Chia Chen Phys. Chem. Chem. Phys., 2017,19, 25471-25477
Additional information on BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)-
Comprehensive Overview of BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)- (CAS No. 627526-67-4)
BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)- (CAS No. 627526-67-4) is a specialized boronic acid derivative that has garnered significant attention in the fields of organic synthesis and pharmaceutical research. This compound, characterized by its naphthalene backbone and fluorine substituent, is widely utilized as a key intermediate in the development of biologically active molecules. Its unique structure enables it to participate in Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern drug discovery and material science.
The growing interest in BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)- is driven by its versatility in medicinal chemistry. Researchers are increasingly exploring its potential in designing targeted therapies, particularly for cancer treatment and neurological disorders. The fluorine atom in its structure enhances its binding affinity and metabolic stability, making it a valuable component in small-molecule inhibitors. Additionally, its boronic acid moiety facilitates interactions with enzyme active sites, further expanding its applications in drug development.
In the context of green chemistry, BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)- aligns with the demand for sustainable synthetic routes. Its role in catalytic processes reduces the need for harsh reagents, contributing to environmentally friendly production methods. This aspect is particularly relevant as industries and academia prioritize eco-conscious practices and reduced waste generation.
From a commercial perspective, the demand for BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)- is rising due to its high purity standards and reproducible synthesis. Suppliers and manufacturers are focusing on scalable production to meet the needs of research institutions and pharmaceutical companies. Quality control measures, such as HPLC analysis and NMR verification, ensure its suitability for high-throughput screening and preclinical studies.
Recent advancements in computational chemistry have further highlighted the potential of BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)-. Molecular docking studies and QSAR modeling have provided insights into its structure-activity relationships, enabling rational drug design. These tools are invaluable for optimizing its pharmacokinetic properties and minimizing off-target effects.
In summary, BORONIC ACID, (5-FLUORO-2-NAPHTHALENYL)- (CAS No. 627526-67-4) is a multifunctional compound with broad applications in scientific research and industrial processes. Its unique chemical properties and compatibility with modern techniques make it a sought-after reagent in the pursuit of innovative solutions for global health challenges.
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