Cas no 627-35-0 (N-Methyl-1-propanamine)

N-Methyl-1-propanamine (CAS 627-35-0) is a secondary amine with the molecular formula C?H??N. This clear, colorless liquid is characterized by its strong ammonia-like odor and high volatility. It serves as a versatile intermediate in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and specialty chemicals. Its reactive secondary amine group enables efficient alkylation and acylation reactions, making it valuable for constructing complex molecular frameworks. The compound exhibits good solubility in common organic solvents, facilitating its use in homogeneous reaction systems. Careful handling is required due to its flammability and potential irritant properties. Storage under inert atmosphere is recommended to maintain stability.
N-Methyl-1-propanamine structure
N-Methyl-1-propanamine structure
Product Name:N-Methyl-1-propanamine
CAS No:627-35-0
MF:C4H11N
MW:73.1368410587311
MDL:MFCD00009361
CID:39232
PubChem ID:24858651
Update Time:2025-05-20

N-Methyl-1-propanamine Chemical and Physical Properties

Names and Identifiers

    • N-Methyl-n-propylamine
    • N-Methylpropylamine
    • N-Methyl-1-propylamine
    • Methyl-N-propylamine
    • N-Methyl-1-propanami
    • N-Methyl-1-propanamine
    • N-methylpropan-1-amine
    • N-Propylmethylamine
    • Propylamine,N-methyl- (6CI,7CI,8CI)
    • Methylpropylamine
    • N-Methylpropanamine
    • methyl(propyl)amine
    • 1-Propanamine, N-methyl-
    • VW1H32H1QM
    • propylmethylamine
    • methyl propylamine
    • methyl-propylamine
    • methylpropyl amine
    • methylpropyl-amine
    • methyl propyl amine
    • methyl-propyl-amine
    • N-methyl-propylamine
    • N-methyl propylamine
    • NSC165652
    • N-methyl-propyl-amine
    • N-
    • MDL: MFCD00009361
    • Inchi: 1S/C4H11N/c1-3-4-5-2/h5H,3-4H2,1-2H3
    • InChI Key: GVWISOJSERXQBM-UHFFFAOYSA-N
    • SMILES: N(C)CCC

Computed Properties

  • Exact Mass: 73.08910
  • Monoisotopic Mass: 73.089149
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 5
  • Rotatable Bond Count: 2
  • Complexity: 13.1
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 0.8
  • Topological Polar Surface Area: 12

Experimental Properties

  • Color/Form: Colorless liquid
  • Density: 0.713?g/mL?at 25?°C(lit.)
  • Melting Point: -60.4°C (estimate)
  • Boiling Point: 63°C(lit.)
  • Flash Point: Fahrenheit: -25.6 ° f
    Celsius: -32 ° c
  • Refractive Index: n20/D 1.394(lit.)
  • PSA: 12.03000
  • LogP: 1.00670
  • Solubility: It is miscible with water.

N-Methyl-1-propanamine Security Information

  • Symbol: GHS02 GHS05
  • Prompt:dangerous
  • Signal Word:Danger
  • Hazard Statement: H225-H314
  • Warning Statement: P210-P280-P305 + P351 + P338-P310
  • Hazardous Material transportation number:UN 2733 3/PG 2
  • WGK Germany:3
  • Hazard Category Code: 11-34
  • Safety Instruction: S16-S26-S27-S36/37/39-S45-S25
  • Hazardous Material Identification: F C
  • HazardClass:3
  • PackingGroup:II
  • Storage Condition:Flammable area
  • Safety Term:3
  • Packing Group:II
  • Risk Phrases:R11; R34

N-Methyl-1-propanamine Customs Data

  • HS CODE:2921199090
  • Customs Data:

    China Customs Code:

    2921199090

    Overview:

    2921199090 Other acyclic monoamines and their derivatives and salts.Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:6.5%.general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

N-Methyl-1-propanamine Pricemore >>

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N-Methyl-1-propanamine Production Method

N-Methyl-1-propanamine Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:627-35-0)N-Methyl-1-propanamine
Order Number:A1203297
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 02:49
Price ($):159.0

N-Methyl-1-propanamine Related Literature

Additional information on N-Methyl-1-propanamine

Professional Introduction to N-Methyl-1-propanamine (CAS No. 627-35-0)

N-Methyl-1-propanamine, chemically known by its CAS number 627-35-0, is a significant compound in the field of pharmaceutical and chemical research. This organic amine plays a crucial role in the synthesis of various bioactive molecules, making it a subject of extensive study and application. Its structural simplicity and reactivity contribute to its versatility, enabling its use in multiple synthetic pathways and industrial processes.

The compound N-Methyl-1-propanamine is an isomer of 1-propanamine, distinguished by the presence of a methyl group attached to the nitrogen atom. This modification enhances its chemical properties, making it more suitable for certain reactions and applications. In pharmaceutical chemistry, this compound serves as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its ability to act as a nucleophile in various reactions allows for the construction of complex molecular frameworks essential for drug development.

Recent advancements in medicinal chemistry have highlighted the importance of N-Methyl-1-propanamine in the design of novel therapeutic agents. Studies have demonstrated its role in the development of drugs targeting neurological disorders, where its structural features contribute to improved binding affinity and selectivity. The compound's ability to undergo functionalization at multiple sites makes it a valuable building block for creating diverse pharmacophores.

In addition to its pharmaceutical applications, N-Methyl-1-propanamine finds utility in agrochemical formulations. Its incorporation into pesticide and herbicide molecules enhances their efficacy by improving solubility and stability. Research has shown that derivatives of this compound can exhibit potent biological activity against various pests, contributing to the development of more sustainable agricultural practices.

The synthesis of N-Methyl-1-propanamine typically involves catalytic amination processes or reductive methylation of propyl nitrile. These methods are optimized for high yield and purity, ensuring that the final product meets stringent quality standards required for industrial applications. Advances in catalytic systems have further improved the efficiency of these synthetic routes, reducing waste and energy consumption.

Industrial-scale production of CAS No. 627-35-0 requires careful consideration of safety and environmental factors. While not classified as a hazardous material, proper handling protocols must be followed to ensure worker safety and prevent environmental contamination. Modern manufacturing facilities employ state-of-the-art containment systems and waste treatment technologies to minimize ecological impact.

The role of N-Methyl-1-propanamine in drug discovery continues to evolve with emerging research findings. Recent studies have explored its potential in developing treatments for infectious diseases, where its structural motifs contribute to the design of novel antibiotics and antiviral agents. The compound's ability to interact with biological targets at multiple levels makes it a promising candidate for therapeutic intervention.

In conclusion, N-Methyl-1-propanamine (CAS No. 627-35-0) is a versatile and indispensable compound in modern chemistry and pharmaceutical research. Its broad range of applications, from drug development to agrochemical formulations, underscores its importance in advancing scientific knowledge and industrial innovation. As research progresses, the full potential of this compound will continue to be uncovered, driving further breakthroughs in multiple fields.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:627-35-0)N-Methyl-1-propanamine
A1203297
Purity:99%
Quantity:25g
Price ($):159.0
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