Cas no 626-64-2 (pyridin-4-ol)
pyridin-4-ol Chemical and Physical Properties
Names and Identifiers
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- Pyridin-4-ol
- Hydroxypyridine(Gamma-)
- 4-Hydroxypyride
- 4HYDROXYPRIDINE
- 4-HYDROXYPYRIDINE ( 4-PYRIDINOL )
- 2-HYDROXY PYRIDINE PYRIDIN-2-OL
- 4-HYDROXY PYRIDINE PYRIDIN-4-OL
- 4-Hydroxypyridine
- 4-(1H)-Pyridone
- 4-Pyridinol
- 1H-Pyridin-4-ol
- 4-hydroxy-pyridine
- 4-hydroxypyridone
- 4-oxypyridine
- 4-Pyridol
- 4-Pyridone
- Hydroxypyridinoxid
- p-hydroxy pyridine
- γ-Pyridone
- pyridin-4(1H)-one
- 4(1H)-Pyridinone
- 4-Oxopyridine
- 4-Pyridinone
- gamma-Hydroxypyridine
- 1H-pyridin-4-one
- gamma-Pyridone
- 4(1H)-Pyridone
- .gamma.-Pyridone
- NSC5080
- GCNTZFIIOFTKIY-UHFFFAOYSA-N
- 3P2MV07G53
- 4-HYDROXYPYRIDINE (4-PYRIDINOL)
- 4-hydroxy pyridine
- 4pyridone
- 4-Pyridineolate
- p-Hydroxypyridine
- 4-hydroxypridine
- Pyridin-4-o
- EINECS 203-633-2
- CS-W007690
- H0332
- AI3-61970
- CHEBI:87614
- HYDROXYPYRIDINE, 4-
- EINECS 222-380-9
- SY112252
- UNII-3P2MV07G53
- HY-W007690
- Q230024
- NS00022560
- 4-Hydroxypyridine, 95%
- CAS-626-64-2
- AKOS000121024
- 3454-03-3
- BRN 0105800
- NSC 146174
- Tox21_303817
- NSC-5080
- EN300-21574
- CHEBI:133125
- 1,4-Dihydro-4-pyridinone
- NSC-26021
- AKOS022377006
- FT-0618743
- STR01041
- W-104968
- MFCD00040458
- SB52275
- CS-0166783
- CHEMBL237459
- NSC146174
- AC-907/34116018
- Pyridin-4-one
- 108-96-3
- NSC-146174
- SR-1C7
- SY003367
- CQG
- D82355
- NCGC00357095-01
- AM20061387
- AC-2927
- Butanoic acid,heptafluoro-,1,10-decanediyl ester(9ci)
- .gamma.-Hydroxypyridine
- BS-3730
- 4-hydroxypyridine, AldrichCPR
- DTXSID2052310
- MFCD00006419
- 5-21-07-00152 (Beilstein Handbook Reference)
- c1201
- A8662
- NSC 5080
- SMR003288679
- InChI=1/C5H5NO/c7-5-1-3-6-4-2-5/h1-4H,(H,6,7
- 626-64-2
- DTXCID9030882
- 1,4-dihydropyridin-4-one
- FT-0618744
- A1E9A648-09AC-4FC9-A7AF-37534D102469
- MLS004491722
- EINECS 210-958-3
- PB17041
- BCP08909
- BBL022970
- DB-040853
- pyridine, 4-hydroxy-
- STL363251
- 4-Pyridinol; 4-Pyridol; NSC 5080; gamma-Hydroxypyridine;
- DB-014976
- 4pyridinol
- FH02024
- 4(1H)-Pyridone (8CI)
- gammaHydroxypyridine
- 203-633-2
- pyridin-4-ol
-
- MDL: MFCD00040458
- Inchi: 1S/C5H5NO/c7-5-1-3-6-4-2-5/h1-4H,(H,6,7)
- InChI Key: GCNTZFIIOFTKIY-UHFFFAOYSA-N
- SMILES: O=C1C=CNC=C1
- BRN: 0105800
Computed Properties
- Exact Mass: 95.03710
- Monoisotopic Mass: 95.037
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 7
- Rotatable Bond Count: 0
- Complexity: 121
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 3
- XLogP3: -1.3
- Topological Polar Surface Area: 29.1
Experimental Properties
- Color/Form: Beige to light brown powder or block.
- Density: 1.1418 (rough estimate)
- Melting Point: 148.0 to 153.0 deg-C
- Boiling Point: 230-235?°C/12?mmHg(lit.)
- Flash Point: 221 oC
- Refractive Index: 1.5939 (estimate)
- Water Partition Coefficient: dissolution
- PSA: 33.12000
- LogP: 0.78720
- Solubility: Soluble in water and ethanol, insoluble in ether and benzene.
- Sensitiveness: Easy to absorb moisture and sensitive to light
- pka: 3.2(at 20℃)
pyridin-4-ol Security Information
-
Symbol:
- Prompt:warning
- Signal Word:Warning
- Hazard Statement: H315,H319,H335
- Warning Statement: P261,P305+P351+P338
- Hazardous Material transportation number:NONH for all modes of transport
- WGK Germany:3
- Hazard Category Code: 22-37/38-41
- Safety Instruction: S26-S36-S37/39
- FLUKA BRAND F CODES:3-8-10
- RTECS:UU7701450
-
Hazardous Material Identification:
- Risk Phrases:R36/37/38
- Safety Term:S26;S37/39
- HazardClass:IRRITANT
- TSCA:Yes
- Storage Condition:Store at room temperature
pyridin-4-ol Customs Data
- HS CODE:2933399090
- Customs Data:
China Customs Code:
2933399090Overview:
2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
pyridin-4-ol Pricemore >>
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| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R003971-100g |
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pyridin-4-ol Suppliers
pyridin-4-ol Related Literature
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Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
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Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
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3. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
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4. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
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Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
Additional information on pyridin-4-ol
Professional Introduction to Pyridin-4-ol (CAS No: 626-64-2)
Pyridin-4-ol, chemically known by the CAS number 626-64-2, is a heterocyclic organic compound that belongs to the pyridine family. This compound features a six-membered aromatic ring containing a nitrogen atom, which is attached to a hydroxyl group at the 4-position. Pyridin-4-ol has garnered significant attention in the field of pharmaceutical chemistry due to its versatile structural properties and potential applications in drug development.
The< strong>structure of Pyridin-4-ol makes it a valuable intermediate in the synthesis of various pharmacologically active compounds. Its ability to serve as a precursor for more complex molecules has been explored in numerous research studies. The presence of both an aromatic ring and a hydroxyl functional group allows for further chemical modifications, making it a versatile building block in medicinal chemistry.
In recent years, Pyridin-4-ol has been studied for its potential role in the development of novel therapeutic agents. One of the most promising areas of research involves its application in the synthesis of antimicrobial agents. The unique chemical properties of Pyridin-4-ol have been leveraged to design compounds with enhanced efficacy against resistant bacterial strains. This has been particularly relevant in the context of rising antibiotic resistance, where innovative approaches are needed to combat infections.
Furthermore, Pyridin-4-ol has shown promise in the development of neurological drugs. Researchers have investigated its potential as a precursor for compounds that target neurological disorders such as Alzheimer's disease and Parkinson's disease. The compound's ability to interact with specific biological pathways has made it a subject of interest for designing molecules that can modulate neuronal activity. Preliminary studies suggest that derivatives of Pyridin-4-ol may have neuroprotective properties, which could be exploited for therapeutic benefit.
The< strong>pharmaceutical industry has also explored Pyridin-4-ol as a key intermediate in the synthesis of cardiovascular drugs. Its structural framework is conducive to developing compounds that can interact with enzymes and receptors involved in regulating blood pressure and cholesterol levels. Several research groups have reported on the successful synthesis of novel cardiovascular agents derived from Pyridin-4-ol, highlighting its importance in this therapeutic area.
In addition to its pharmaceutical applications, Pyridin-4-ol has found utility in agrochemical research. The compound's structural features make it suitable for developing pesticides and herbicides that are effective against various crop pathogens. Its role as an intermediate in synthesizing biologically active agrochemicals underscores its versatility beyond pharmaceuticals.
The< strong>synthesis of Pyridin-4-ol can be achieved through several chemical pathways, including condensation reactions and hydroxylation processes. Modern synthetic methods have improved the efficiency and yield of these reactions, making Pyridin-4-ol more accessible for industrial applications. Advances in green chemistry have also led to the development of more environmentally friendly synthetic routes, reducing waste and energy consumption.
In conclusion, Pyridin-4-ol (CAS No: 626-64-2) is a multifaceted compound with significant potential in various fields, particularly pharmaceuticals and agrochemicals. Its unique structure and reactivity make it a valuable building block for synthesizing biologically active molecules. Ongoing research continues to uncover new applications for Pyridin-4-ol, reinforcing its importance as a key intermediate in modern chemistry.
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