• 1. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
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• 2. Excellent humidity sensor based on ultrathin HKUST-1 nanosheets?
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• 3. Emerging investigator series: first-principles and thermodynamics comparison of compositionally-tuned delafossites: cation release from the (001) surface of complex metal oxides?
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• 4. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer?
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Benzothiophenes 1-benzothiophenes

3-Chloro-1-benzothiophene-2-carbohydrazide (CAS No. 62524-21-4): A Versatile Chemical Intermediate for Modern Applications

3-Chloro-1-benzothiophene-2-carbohydrazide (CAS No. 62524-21-4) is a specialized organic compound that has garnered significant attention in pharmaceutical and material science research. This benzothiophene derivative features a unique molecular structure combining a chloro-substituted benzothiophene core with a reactive carbohydrazide functional group, making it valuable for synthesizing complex molecules. Researchers frequently search for "3-Chloro-1-benzothiophene-2-carbohydrazide uses" and "CAS 62524-21-4 suppliers," reflecting its growing importance in drug discovery.

The compound's molecular formula C9H7ClN2OS and molecular weight 226.68 g/mol position it as a crucial intermediate in medicinal chemistry. Recent studies highlight its role in developing kinase inhibitors, a hot topic in cancer research, as evidenced by searches for "benzothiophene-based drug candidates 2024." Its chloro group offers excellent reactivity for cross-coupling reactions, while the hydrazide moiety enables condensation reactions—key features that organic chemists explore when searching "how to modify benzothiophene carbohydrazide."

In material science, 3-Chloro-1-benzothiophene-2-carbohydrazide contributes to developing organic semiconductors and photovoltaic materials, aligning with the booming interest in "sustainable electronic materials." The compound's extended π-conjugation system makes it valuable for designing OLED components, responding to frequent queries about "benzothiophene derivatives for optoelectronics." Analytical chemists also utilize it as a chromogenic reagent for metal ion detection, addressing laboratory needs reflected in searches for "selective chemical sensors."

The global market for benzothiophene derivatives shows consistent growth, with 3-Chloro-1-benzothiophene-2-carbohydrazide maintaining steady demand among pharmaceutical intermediates suppliers. Industry reports tracking "specialty chemicals market trends 2024" highlight its relevance. Proper handling requires standard laboratory precautions—users often seek "3-Chloro-1-benzothiophene-2-carbohydrazide safety data" and "storage conditions for heterocyclic carbohydrazides," emphasizing the need for technical documentation.

Recent patent literature reveals innovative applications of CAS 62524-21-4 in developing antimicrobial agents, particularly against drug-resistant strains—a pressing concern reflected in searches for "new antibiotic scaffolds." Its structural features enable researchers to create bioactive molecular hybrids, answering frequent queries about "multifunctional heterocyclic compounds." The compound's crystallographic properties also interest materials scientists investigating "molecular packing in organic crystals."

Quality specifications for 3-Chloro-1-benzothiophene-2-carbohydrazide typically require ≥98% purity, with advanced analytical techniques like HPLC-MS ensuring batch consistency—details often sought under "analytical methods for benzothiophene derivatives." The compound's solubility profile (soluble in DMSO, DMF; sparingly soluble in ethanol) makes it versatile for various reaction conditions, addressing practical questions about "handling chloro-substituted heterocycles."

Environmental considerations drive research into green synthesis routes for 3-Chloro-1-benzothiophene-2-carbohydrazide, matching industry searches for "sustainable heterocycle production." Computational chemistry studies predict its electronic properties and reactivity patterns, resources frequently accessed under "DFT studies on benzothiophene derivatives." These multidimensional applications ensure its continued relevance across scientific disciplines.

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