Cas no 62458-92-8 (2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One)

2-Amino-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one is a heterocyclic compound featuring a fused pyridine-pyrimidine core with a benzyl substituent. This structure imparts potential utility as a versatile intermediate in medicinal chemistry, particularly in the synthesis of kinase inhibitors and other biologically active molecules. The presence of both amino and carbonyl functional groups enhances its reactivity, enabling diverse derivatization pathways. Its tetrahydropyrido scaffold may contribute to improved solubility and bioavailability compared to fully aromatic analogs. The compound's rigid framework offers stereochemical control in further synthetic modifications. Careful handling is advised due to the presence of reactive sites. Storage under inert conditions is recommended to maintain stability.
2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One structure
62458-92-8 structure
Product Name:2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One
CAS No:62458-92-8
MF:C14H16N4O
MW:256.303042411804
CID:444028
PubChem ID:135553000
Update Time:2025-05-24

2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One Chemical and Physical Properties

Names and Identifiers

    • 2-Amino-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one
    • 2-amino-7-benzyl-1,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-4-one
    • CS-0083453
    • SCHEMBL15189148
    • AKOS022172440
    • AM807715
    • AS-32317
    • 2-amino-7-benzyl-5,6,7,8-tetrahydropyrido-[3,4-d]pyrimidin-4(3H)-one
    • 2-Amino-7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyrimidin-4-one
    • 62458-92-8
    • PUDMEXIJNZOGIC-UHFFFAOYSA-N
    • 2-amino-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-ol
    • 2-Amino-7-benzyl-5,6,7,8-tetrahydro-1H-pyrido[3,4-d]pyrimidin-4-one
    • DTXSID00487034
    • 2-amino-7-benzyl-3,5,6,8-tetrahydropyrido[3,4-d]pyrimidin-4-one
    • SCHEMBL721339
    • 2-Amino-7-benzyl-5,6,7,8-tetrahydro-pyrido[3,4-d]pyrimidin-4-ol
    • DB-292915
    • 2-AMINO-7-BENZYL-3H,5H,6H,8H-PYRIDO[3,4-D]PYRIMIDIN-4-ONE
    • 2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One
    • MDL： MFCD24843097
    • Inchi： 1S/C14H16N4O/c15-14-16-12-9-18(7-6-11(12)13(19)17-14)8-10-4-2-1-3-5-10/h1-5H,6-9H2,(H3,15,16,17,19)
    • InChI Key： PUDMEXIJNZOGIC-UHFFFAOYSA-N
    • SMILES： O=C1C2=C(CN(CC3C=CC=CC=3)CC2)N=C(N)N1

Computed Properties

  • Exact Mass: 256.13241115g/mol
  • Monoisotopic Mass: 256.13241115g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 19
  • Rotatable Bond Count: 2
  • Complexity: 435
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.1
  • Topological Polar Surface Area: 70.7?2

2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
A579318-50mg
2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4(3h)-One
 62458-92-8
50mg
 $ 50.00 2022-06-08
TRC
A579318-100mg
2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4(3h)-One
 62458-92-8
100mg
 $ 95.00 2022-06-08
TRC
A579318-500mg
2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidin-4(3h)-One
 62458-92-8
500mg
 $ 320.00 2022-06-08
Chemenu
CM123151-1g
2-amino-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one
 62458-92-8 95%
1g
 $*** 2023-05-30
Alichem
A029185123-1g
2-Amino-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one
 62458-92-8 95%
1g
 $363.12 2023-09-01
Alichem
A029185123-5g
2-Amino-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one
 62458-92-8 95%
5g
 $1069.00 2023-09-01
1PlusChem
1P00EKSK-1g
2-AMino-7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyriMidin-4-one
 62458-92-8 98%
1g
 $295.00 2024-04-22
1PlusChem
1P00EKSK-5g
2-AMino-7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyriMidin-4-one
 62458-92-8 98%
5g
 $942.00 2024-04-22
1PlusChem
1P00EKSK-10g
2-AMino-7-benzyl-5,6,7,8-tetrahydro-3H-pyrido[3,4-d]pyriMidin-4-one
 62458-92-8 98%
10g
 $1585.00 2024-04-22
A2B Chem LLC
AG79332-1g
2-Amino-7-benzyl-5,6,7,8-tetrahydro-pyrido[3,4-d]pyrimidin-4-ol
 62458-92-8 98%
1g
 $236.00 2024-04-19

2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One Related Literature

Related Categories

Additional information on 2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One

Recent Advances in the Study of 2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One (CAS: 62458-92-8)

The compound 2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One (CAS: 62458-92-8) has garnered significant attention in the field of chemical biology and medicinal chemistry due to its potential therapeutic applications. Recent studies have explored its role as a key intermediate in the synthesis of bioactive molecules and its direct pharmacological effects. This research brief consolidates the latest findings to provide a comprehensive overview of its current status in drug discovery and development.

Recent investigations into the pharmacological properties of 2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One have highlighted its potential as a kinase inhibitor. Kinases play a crucial role in various cellular processes, and their dysregulation is implicated in numerous diseases, including cancer and inflammatory disorders. Preliminary in vitro studies indicate that this compound exhibits selective inhibition against specific kinase targets, suggesting its utility in targeted therapy development. Further mechanistic studies are underway to elucidate its binding affinity and selectivity profile.

In addition to its kinase inhibitory activity, 2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One has been investigated for its role in modulating cellular signaling pathways. Recent research has demonstrated its ability to influence key pathways such as PI3K/AKT and MAPK, which are critical in cell proliferation and survival. These findings open new avenues for the development of novel therapeutics targeting these pathways, particularly in oncology and autoimmune diseases.

The synthetic accessibility of 2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One has also been a focus of recent studies. Advances in synthetic methodologies have enabled the efficient production of this compound with high purity and yield, facilitating its use in both research and potential clinical applications. Researchers have optimized reaction conditions to minimize by-products and improve scalability, addressing previous challenges in its synthesis.

Despite these promising developments, challenges remain in the clinical translation of 2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One. Pharmacokinetic studies are needed to assess its bioavailability, metabolic stability, and toxicity profile. Current efforts are focused on structural modifications to enhance its drug-like properties while retaining its biological activity. Collaborative research between academic institutions and pharmaceutical companies is expected to accelerate its progression toward preclinical and clinical evaluation.

In conclusion, 2-Amino-7-Benzyl-5,6,7,8-Tetrahydropyrido3,4-DPyrimidin-4(3h)-One (CAS: 62458-92-8) represents a promising scaffold in medicinal chemistry with diverse therapeutic potential. Ongoing research aims to fully characterize its biological activities and optimize its properties for drug development. The compound's dual role as a kinase inhibitor and modulator of cellular signaling pathways underscores its significance in the pursuit of novel treatments for complex diseases.

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