Cas no 62456-32-0 (8-Bromonaphthalen-1-ol)

8-Bromonaphthalen-1-ol is a brominated naphthol derivative with the molecular formula C??H?BrO. This compound is characterized by the presence of a hydroxyl group at the 1-position and a bromine substituent at the 8-position of the naphthalene ring, making it a valuable intermediate in organic synthesis. Its structural features enable applications in the preparation of pharmaceuticals, agrochemicals, and functional materials. The bromine atom enhances reactivity for further cross-coupling reactions, while the hydroxyl group offers a site for derivatization. The compound exhibits moderate stability under standard conditions, ensuring ease of handling in laboratory settings. Its well-defined reactivity profile makes it a useful building block for complex molecular architectures.
8-Bromonaphthalen-1-ol structure
8-Bromonaphthalen-1-ol structure
Product Name:8-Bromonaphthalen-1-ol
CAS No:62456-32-0
MF:C10H7BrO
MW:223.065982103348
MDL:MFCD17012355
CID:444221
Update Time:2025-06-14

8-Bromonaphthalen-1-ol Chemical and Physical Properties

Names and Identifiers

    • 1-Naphthalenol, 8-bromo-
    • 1-Hydroxy-8-bromonaphthalene
    • 8-Bromonaphthalen-1-ol
    • 8-bromo-1-naphthol
    • 8-Bromonaphth-1-ol
    • 1-Bromo-8-naphthol
    • AK311022
    • X4957
    • MDL: MFCD17012355
    • Inchi: 1S/C10H7BrO/c11-8-5-1-3-7-4-2-6-9(12)10(7)8/h1-6,12H
    • InChI Key: RJUFYSUNQJMDLZ-UHFFFAOYSA-N
    • SMILES: BrC1=CC=CC2=CC=CC(=C21)O

Computed Properties

  • Exact Mass: 221.96801
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 0
  • Complexity: 160
  • Topological Polar Surface Area: 20.2

Experimental Properties

  • PSA: 20.23

8-Bromonaphthalen-1-ol Pricemore >>

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Additional information on 8-Bromonaphthalen-1-ol

Comprehensive Analysis of 8-Bromonaphthalen-1-ol (CAS No. 62456-32-0): Properties, Applications, and Industry Insights

8-Bromonaphthalen-1-ol (CAS No. 62456-32-0) is a halogenated naphthalene derivative widely recognized for its versatile applications in organic synthesis, pharmaceuticals, and material science. This compound, characterized by a bromine substituent at the 8-position and a hydroxyl group at the 1-position of the naphthalene ring, exhibits unique chemical properties that make it valuable for researchers and industrial applications. With the growing demand for halogenated aromatic compounds in drug discovery and advanced materials, 8-Bromonaphthalen-1-ol has garnered significant attention in recent years.

The molecular structure of 8-Bromonaphthalen-1-ol (C10H7BrO) combines the stability of naphthalene with the reactivity of bromine and hydroxyl functional groups. This dual functionality enables its use as a building block in cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig couplings, which are pivotal in creating complex organic molecules. Researchers frequently search for "8-Bromonaphthalen-1-ol synthesis" or "CAS 62456-32-0 applications," reflecting its importance in modern synthetic chemistry.

In the pharmaceutical sector, 8-Bromonaphthalen-1-ol serves as a precursor for developing bioactive molecules and fluorescent probes. Its bromine atom allows for further functionalization, making it a key intermediate in designing targeted therapies. Recent studies highlight its potential in cancer research and neurodegenerative disease studies, aligning with trending topics like "halogenated drug intermediates" and "small-molecule therapeutics."

Material scientists leverage 8-Bromonaphthalen-1-ol to develop organic semiconductors and luminescent materials. Its naphthalene core contributes to π-conjugation, essential for optoelectronic devices such as OLEDs and solar cells. Queries like "naphthalene derivatives for OLEDs" or "CAS 62456-32-0 in material science" underscore its relevance in sustainable technology innovations.

Environmental and safety considerations are critical when handling 8-Bromonaphthalen-1-ol. While not classified as hazardous under standard conditions, proper storage (away from light and moisture) and handling protocols are recommended. This aligns with the increasing focus on "green chemistry alternatives" and "sustainable chemical synthesis," which dominate current industry discussions.

In summary, 8-Bromonaphthalen-1-ol (CAS No. 62456-32-0) bridges multiple scientific disciplines, from medicinal chemistry to advanced materials engineering. Its adaptability to diverse reactions and applications ensures its continued prominence in research and industrial workflows. For those exploring "buy 8-Bromonaphthalen-1-ol" or "technical specifications of CAS 62456-32-0," understanding its multifaceted roles is essential for optimizing its use in cutting-edge innovations.

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