Cas no 62456-11-5 (2-(3-hydroxypropyl)cyclohexan-1-one)

2-(3-Hydroxypropyl)cyclohexan-1-one is a cyclic ketone derivative featuring a hydroxypropyl substituent at the 2-position of the cyclohexanone ring. This compound is of interest in synthetic organic chemistry due to its bifunctional structure, combining a reactive ketone group with a hydroxyl moiety, enabling its use as a versatile intermediate in the preparation of more complex molecules. The presence of both functional groups allows for selective modifications, such as oxidation, reduction, or further derivatization, making it valuable for applications in pharmaceuticals, fragrances, and specialty chemicals. Its stable cyclohexane backbone contributes to predictable reactivity and handling under standard laboratory conditions.
2-(3-hydroxypropyl)cyclohexan-1-one structure
62456-11-5 structure
Product Name:2-(3-hydroxypropyl)cyclohexan-1-one
CAS No:62456-11-5
MF:C9H16O2
MW:156.222143173218
MDL:MFCD00619645
CID:444236
PubChem ID:12244234
Update Time:2025-05-21

2-(3-hydroxypropyl)cyclohexan-1-one Chemical and Physical Properties

Names and Identifiers

    • Cyclohexanone, 2-(3-hydroxypropyl)-
    • 2-(3-hydroxypropyl)cyclohexan-1-one
    • AKOS015907259
    • SCHEMBL11595453
    • EN300-219321
    • 62456-11-5
    • 2-(3-hydroxy-propyl)-cyclohexan-1-one
    • 2-(3-hydroxypropyl)cyclohexanone
    • DTXSID00482120
    • MDL: MFCD00619645
    • Inchi: 1S/C9H16O2/c10-7-3-5-8-4-1-2-6-9(8)11/h8,10H,1-7H2
    • InChI Key: JPUCVMZNPZFTQD-UHFFFAOYSA-N
    • SMILES: O=C1CCCCC1CCCO

Computed Properties

  • Exact Mass: 156.11508
  • Monoisotopic Mass: 156.115029749g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 3
  • Complexity: 132
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1
  • Topological Polar Surface Area: 37.3?2

Experimental Properties

  • PSA: 37.3

2-(3-hydroxypropyl)cyclohexan-1-one Pricemore >>

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Additional information on 2-(3-hydroxypropyl)cyclohexan-1-one

Research Brief on 2-(3-hydroxypropyl)cyclohexan-1-one (CAS: 62456-11-5) in Chemical Biology and Pharmaceutical Applications

The compound 2-(3-hydroxypropyl)cyclohexan-1-one (CAS: 62456-11-5) has recently garnered significant attention in the field of chemical biology and pharmaceutical research due to its versatile applications in drug discovery and development. This research brief synthesizes the latest findings on this compound, focusing on its synthesis, biological activities, and potential therapeutic uses. The growing interest in this molecule is driven by its unique structural features, which make it a promising candidate for various medicinal chemistry applications.

Recent studies have explored the synthetic pathways for 2-(3-hydroxypropyl)cyclohexan-1-one, highlighting its efficient production through catalytic hydrogenation and other advanced chemical methods. Researchers have optimized reaction conditions to achieve high yields and purity, which are critical for its subsequent use in pharmaceutical formulations. The compound's structural flexibility allows for further derivatization, enabling the development of novel analogs with enhanced biological activities.

In terms of biological applications, 2-(3-hydroxypropyl)cyclohexan-1-one has demonstrated notable pharmacological properties, including anti-inflammatory and antimicrobial effects. Preliminary in vitro studies indicate its potential as a lead compound for treating inflammatory diseases, with mechanisms involving the modulation of key signaling pathways such as NF-κB. Additionally, its antimicrobial activity against a range of pathogens suggests its utility in addressing antibiotic resistance, a pressing global health challenge.

Further investigations into the compound's pharmacokinetics and toxicity profiles are underway to assess its suitability for clinical development. Early results suggest favorable bioavailability and low toxicity, positioning it as a viable candidate for further preclinical testing. Researchers are also exploring its potential in combination therapies, where it may enhance the efficacy of existing drugs or reduce adverse effects.

In conclusion, 2-(3-hydroxypropyl)cyclohexan-1-one (CAS: 62456-11-5) represents a promising molecule in the chemical biology and pharmaceutical landscape. Its multifaceted applications, from drug synthesis to therapeutic use, underscore its importance in ongoing research efforts. Future studies will likely focus on expanding its therapeutic scope and optimizing its properties for clinical translation, making it a compound of significant interest for researchers and industry professionals alike.

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