• 1. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?
  Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
• 2. Fate of nitrogen-15 in the subsequent growing season of greenhouse tomato plants (Lycopersicon esculentum Mill) as influenced by alternate partial root-zone irrigation
  Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
• 3. Examination of the hydrogen-bonding networks in small water clusters (n = 2–5, 13, 17) using absolutely localized molecular orbital energy decomposition analysis?
  Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
• 4. Excellent lithium ion storage property of porous MnCo2O4 nanorods?
  Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
• 5. Distinction of trans–cis photoisomers with comparable optical properties in multiple-state photochromic systems – examining a molecule with three azobenzenes via in situ irradiation NMR spectroscopy?
  Jonas Kind,Lukas Kaltschnee,Martin Leyendecker,Christina M. Thiele Chem. Commun., 2016,52, 12506-12509

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles Pyrazole carboxylic acids and derivatives
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles Pyrazoles Pyrazole carboxylic acids and derivatives

Comprehensive Overview of Ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine-2-carboxylate (CAS No. 623565-57-1)

Ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine-2-carboxylate (CAS No. 623565-57-1) is a heterocyclic compound that has garnered significant attention in pharmaceutical and agrochemical research due to its unique structural framework. This pyrazolo-oxazine derivative is characterized by a fused bicyclic system, combining pyrazole and oxazine rings, which imparts remarkable chemical versatility. Researchers are increasingly exploring its potential as a building block for drug discovery, particularly in the development of central nervous system (CNS) therapeutics and anti-inflammatory agents.

The compound's ethyl carboxylate moiety enhances its solubility and reactivity, making it a valuable intermediate in organic synthesis. Recent studies highlight its role in catalyzed cross-coupling reactions, a hot topic in green chemistry and sustainable synthesis. As the demand for eco-friendly chemical processes grows, Ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine-2-carboxylate is being investigated for its compatibility with biocatalysts and microwave-assisted synthesis techniques, which align with the industry's shift toward energy-efficient methodologies.

In the context of pharmaceutical applications, this compound has shown promise in modulating GABA receptors, a key target for anxiolytic and anticonvulsant drugs. Its structural similarity to other bioactive heterocycles has spurred interest in its potential to address neurodegenerative disorders, a pressing concern in aging populations. Additionally, its low toxicity profile and high bioavailability make it a candidate for preclinical studies, particularly in neuropharmacology.

From a commercial perspective, CAS No. 623565-57-1 is gaining traction in the fine chemicals market, driven by its applicability in high-value specialty chemicals. Suppliers and manufacturers are optimizing large-scale production protocols to meet the rising demand from contract research organizations (CROs) and academic laboratories. Quality control measures, such as HPLC purity testing and spectroscopic characterization, are critical to ensuring its consistency for research-grade applications.

The compound's relevance extends to material science, where its aromatic heterocycles contribute to the design of organic electronic materials. With the surge in interest for flexible electronics and optoelectronic devices, researchers are evaluating its derivatives for charge transport properties. This interdisciplinary potential positions Ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine-2-carboxylate as a molecule of interest beyond traditional medicinal chemistry.

In summary, Ethyl 6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine-2-carboxylate (CAS No. 623565-57-1) exemplifies the convergence of chemical innovation and multidisciplinary research. Its adaptability across pharmaceuticals, agrochemicals, and advanced materials underscores its value in addressing contemporary scientific challenges. As computational chemistry and AI-driven drug design advance, this compound is poised to play a pivotal role in the next generation of small-molecule therapeutics and functional materials.

• 349494-87-7(5-Ethoxycarbonyl-2-ethylpyrazole-3-carboxylic acid)
• 50920-64-4(Ethyl 1-ethyl-3-methyl-1H-pyrazole-5-carboxylate)
• 50920-45-1(ethyl 1-ethyl-5-methyl-1H-pyrazole-3-carboxylate)
• 88398-71-4(Methyl 1-Ethyl-5-methyl-pyrazole-3-carboxylate)
• 623564-77-2(6,7-dihydro-4-oxo-4H-Pyrazolo[5,1-c][1,4]oxazine-2-carboxaldehyde)
• 1219694-53-7(4H,6H,7H-pyrazolo[3,2-c][1,4]oxazine-2-carboxylic acid)
• 1006348-92-0(Methyl 1-(2-ethoxy-2-oxoethyl)-1H-pyrazole-5-carboxylate)
• 39658-15-6(ethyl 3-methyl-1-propyl-1H-pyrazole-5-carboxylate)
• 1007460-78-7(ethyl 1-ethyl-1H-pyrazole-5-carboxylate)
• 88398-73-6(Methyl 1-ethyl-3-methyl-1H-pyrazole-5-carboxylate)