• 1. Evidence of field induced slow magnetic relaxation in cis-[Co(hfac)2(H2O)2] exhibiting tri-axial anisotropy with a negative axial component?
  Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
• 2. Excellent peroxidase mimicking property of CuO/Pt nanocomposites and their application as an ascorbic acid sensor?
  Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
• 3. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
  Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
• 4. Emerging investigator series: bacteriophages as nano engineering tools for quality monitoring and pathogen detection in water and wastewater
  Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
• 5. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305

Benzoic acid, 5-chloro-2-propoxy-

Benzoic acid, 5-chloro-2-propoxy-benzene, also known by its CAS number 62176-15-2, is a substituted aromatic carboxylic acid with unique structural and chemical properties. This compound belongs to the family of chlorinated benzoic acids and incorporates a propoxy group at the ortho position relative to the chlorine atom. Its structure makes it an interesting subject for research in various fields, including organic chemistry, pharmacology, and materials science.

The 5-chloro-2-propoxy-benzene carboxylic acid has gained attention due to its potential applications in medicinal chemistry. The presence of the chlorine atom at the meta position relative to the carboxylic acid group introduces electronic effects that can influence the compound's reactivity and biological activity. Similarly, the propoxy substituent adds steric and electronic complexity, which may modulate interactions with biological systems.

Recent studies have explored the biological activity of this compound, particularly in the context of its antimicrobial properties. Research published in 2023 has shown that 5-chloro-2-propoxy-benzoic acid exhibits significant bacterial growth inhibition against several strains of *E. coli* and *Staphylococcus aureus*. These findings suggest that the compound may serve as a potential lead in the development of novel antibiotics or antimicrobial agents.

Another area of interest is the chemical synthesis of 5-chloro-2-propoxy-benzoic acid. The compound can be synthesized via various routes, including the Friedel-Crafts alkylation followed by oxidation to the carboxylic acid. Its synthesis has been optimized in recent years, with studies focusing on improving yield, reducing reaction time, and minimizing the use of hazardous reagents.

Additionally, the compound's physical properties have been extensively studied. It has a melting point of approximately 145°C and is soluble in common organic solvents such as dichloromethane and ethyl acetate. These properties make it suitable for various crystallization studies and purification processes in organic chemistry.

In terms of toxicological evaluation, 5-chloro-2-propoxy-benzoic acid has been tested for its acute toxicity in animal models. Results indicate that the compound is relatively nontoxic at low doses, which aligns with its potential use in pharmaceutical formulations.

Recent advancements in computational chemistry have also contributed to understanding the behavior of 5-chloro-2-propoxy-benzoic acid. Molecular modeling studies have provided insights into its binding affinity to various biological targets, such as enzymes and receptors, which are crucial for drug discovery.

Moreover, the compound has been explored for its potential in nanomedicine applications. Its ability to form stable nanoparticles with certain polymers suggests that it could be used as a drug delivery system component.

• 201150-65-4(4,5-Dichloro-2-methoxybenzoic acid)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)