Cas no 62141-26-8 (ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate)

Ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate is a versatile cyclic ketal ester with applications in organic synthesis and pharmaceutical intermediates. Its spirocyclic structure provides stability and reactivity, making it useful for controlled functionalization in complex molecule construction. The compound features a protected carbonyl group, enabling selective transformations under mild conditions. Its ester functionality allows for further derivatization, including hydrolysis or reduction, to yield valuable intermediates. The 1,4-dioxaspiro[4.5]decane moiety enhances solubility in organic solvents, facilitating handling in synthetic workflows. This compound is particularly valuable in multistep syntheses requiring orthogonal protecting group strategies or stereochemical control. Its balanced reactivity profile makes it a practical choice for fine chemical and medicinal chemistry applications.
ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate structure
62141-26-8 structure
Product Name:ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate
CAS No:62141-26-8
MF:C12H20O4
MW:228.284804344177
MDL:MFCD07779435
CID:456721
PubChem ID:15700391
Update Time:2025-05-20

ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate Chemical and Physical Properties

Names and Identifiers

    • 1,4-Dioxaspiro[4.5]decane-8-acetic acid, ethyl ester
    • (1,4-dioxa-spiro[4,5]dec-8-yl)-acetic acid ethyl ester
    • (1,4-DIOXA-SPIRO[4.5]DEC-8-YL)-ACETIC ACID ETHYL ESTER
    • ETHYL 2-(1,4-DIOXASPIRO[4.5]DECAN-8-YL)ACETATE
    • ethyl 1,4-dioxaspiro[4.5]decane-8-acetate
    • ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate
    • MFGQIZPUMIISPR-UHFFFAOYSA-N
    • 3625AH
    • NE54286
    • SY156320
    • Ethyl 1,4-dioxaspiro[4.5]dec-8-ylacetate
    • ethyl 1,4-dioxaspiro[4,5]decane-8-acet
    • 8-ethoxycarbonylmethyl-1,4-dioxaspiro[4.5]decane
    • (1,4-dioxaspiro[4,5]dec-8-yl)acetic acid ethyl ester
    • AB7194
    • SCHEMBL169393
    • Ethyl 2-(1,4-dioxaspiro[4.5]dec-8-yl)acetate
    • MFCD07779435
    • CS-13408
    • DTXSID60577026
    • 62141-26-8
    • AKOS027325870
    • Ethyl (1,4-dioxaspiro[4.5]decan-8-yl)acetate
    • CS-M1350
    • SB37965
    • ethyl2-(1,4-dioxaspiro[4.5]decan-8-yl)acetate
    • EN300-141283
    • ethyl 1,4-dioxaspiro[4,5]decane-8-acetate
    • DB-335825
    • MDL: MFCD07779435
    • Inchi: 1S/C12H20O4/c1-2-14-11(13)9-10-3-5-12(6-4-10)15-7-8-16-12/h10H,2-9H2,1H3
    • InChI Key: MFGQIZPUMIISPR-UHFFFAOYSA-N
    • SMILES: O1CCOC21CCC(CC(=O)OCC)CC2

Computed Properties

  • Exact Mass: 228.1362
  • Monoisotopic Mass: 228.13615911g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 4
  • Complexity: 235
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 44.8
  • XLogP3: 1.3

Experimental Properties

  • PSA: 44.76

ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate Pricemore >>

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ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate Related Literature

Additional information on ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate

Ethyl 2-{1,4-Dioxaspiro[4.5]Decan-8-yl}Acetate: A Comprehensive Overview

Ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate, also known by its CAS number 62141-26-8, is a unique organic compound with a complex structure that has garnered attention in various scientific and industrial applications. This compound belongs to the class of spiro compounds, which are characterized by two rings sharing a single atom. The spiro structure in this molecule is further modified by the presence of a dioxane ring and an acetate group, making it a versatile compound with potential applications in pharmaceuticals, materials science, and advanced chemical synthesis.

The molecular structure of ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate is defined by its spirocyclic framework. The spiro ring system consists of a five-membered ring (spiro[4.5]) fused with a six-membered dioxane ring. This arrangement creates a rigid yet flexible structure that can accommodate various functional groups. The acetate group attached to the spiro system introduces additional reactivity and solubility properties, making it suitable for a wide range of chemical reactions.

Recent studies have highlighted the potential of spiro compounds like ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate in drug delivery systems. Researchers have explored the use of this compound as a precursor for bioactive molecules due to its ability to form stable ester linkages and its compatibility with various functionalization techniques. Additionally, the compound's unique electronic properties have been leveraged in the development of advanced materials, such as stimuli-responsive polymers and self-healing materials.

In terms of synthesis, ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate can be prepared through a variety of methods, including ring-closing metathesis and traditional organic synthesis techniques. The choice of synthesis method depends on the desired scale of production and the specific requirements of the application. Recent advancements in catalytic methods have made it possible to achieve higher yields and better control over the stereochemistry of the product.

The physical properties of ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate include a melting point of approximately 70°C and a boiling point around 300°C under standard conditions. Its solubility in common organic solvents such as dichloromethane and ethyl acetate makes it easy to handle in laboratory settings. The compound is also relatively stable under ambient conditions, though it may undergo hydrolysis under acidic or basic conditions.

One of the most promising applications of ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate is in the field of polymer chemistry. Scientists have investigated its use as a building block for synthesizing novel polymers with tailored properties. For instance, its ability to form cross-linked networks has been exploited in the development of high-performance adhesives and coatings that exhibit excellent mechanical strength and thermal stability.

Moreover, ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate has shown potential in green chemistry initiatives due to its compatibility with environmentally friendly reaction conditions. Researchers have demonstrated that this compound can be synthesized using renewable feedstocks and catalyzed by enzymes or other biocompatible catalysts, reducing the environmental footprint associated with traditional chemical manufacturing processes.

In conclusion, ethyl 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetate (CAS No: 62141-26-8) is a versatile compound with a rich structural diversity that opens up numerous possibilities for innovation across various industries. Its unique properties make it an invaluable tool for scientists and engineers seeking to develop advanced materials and sustainable chemical processes.

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