Cas no 621-43-2 (2-(3,4-Diaminophenyl)acetic Acid)

2-(3,4-Diaminophenyl)acetic acid is a versatile aromatic compound featuring both amino and carboxylic acid functional groups, making it a valuable intermediate in organic synthesis and pharmaceutical applications. Its diamine substitution at the 3,4-positions enhances reactivity, facilitating its use in the preparation of heterocyclic compounds, dyes, and coordination complexes. The presence of the acetic acid moiety further expands its utility in conjugation and derivatization reactions. This compound is particularly useful in medicinal chemistry for designing bioactive molecules due to its ability to participate in amide bond formation and metal chelation. High purity grades ensure consistent performance in research and industrial processes.
2-(3,4-Diaminophenyl)acetic Acid structure
621-43-2 structure
Product Name:2-(3,4-Diaminophenyl)acetic Acid
CAS No:621-43-2
MF:C8H10N2O2
MW:166.177201747894
MDL:MFCD09842460
CID:1636222
PubChem ID:431943
Update Time:2025-06-12

2-(3,4-Diaminophenyl)acetic Acid Chemical and Physical Properties

Names and Identifiers

    • (3,4-diaminophenyl)acetic Acid
    • CTK8C3069
    • AK104065
    • tert-Butyl (3,4-diaminophenyl)carbamate
    • KB-55574
    • (3,4-Diamino-phenyl)-essigsaeure
    • (3,4-diamino-phenyl)-carbamic acid tert-butyl ester
    • (3,4-diamino-phenyl)-acetic acid
    • N-(3,4-Diaminophenyl)carbamic acid,1,1-dimethyl ethyl ester
    • tert-butyl 3,4-diaminophenylcarbamate
    • ANW-69629
    • 3,4-diaminoBenzeneacetic acid
    • ACETAMIDE,N-[5-[BIS[2-(ACETYLOXY)ETHYL]AMINO]-2-[(2-CHLORO-5-NITROPHENYL)AZO]PHENYL]-
    • BENZENEACETIC ACID, 3,4-DIAMINO-
    • 2-(3,4-diaminophenyl)acetic Acid
    • 3,4-diaminophenylacetic acid
    • LIOBPVZSSVYQSS-UHFFFAOYSA-N
    • AB9013
    • DB-073057
    • 2-(3,4-diaminophenyl)aceticAcid
    • AKOS005266502
    • A853290
    • MFCD09842460
    • AS-44937
    • EN300-170917
    • 621-43-2
    • SCHEMBL1000171
    • 2-(3,4-Diaminophenyl)acetic Acid
    • MDL： MFCD09842460
    • Inchi： 1S/C8H10N2O2/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3H,4,9-10H2,(H,11,12)
    • InChI Key： LIOBPVZSSVYQSS-UHFFFAOYSA-N
    • SMILES： OC(CC1C=CC(=C(C=1)N)N)=O

Computed Properties

  • Exact Mass: 166.0743
  • Monoisotopic Mass: 166.074227566g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 172
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.3
  • Topological Polar Surface Area: 89.3

Experimental Properties

  • PSA: 89.34

2-(3,4-Diaminophenyl)acetic Acid Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
eNovation Chemicals LLC
D752387-250mg
BENZENEACETIC ACID, 3,4-DIAMINO-
 621-43-2 95%
250mg
 $455 2024-06-06
eNovation Chemicals LLC
D752387-1g
BENZENEACETIC ACID, 3,4-DIAMINO-
 621-43-2 95%
1g
 $1010 2024-06-06
abcr
AB446563-250 mg
2-(3,4-Diaminophenyl)acetic acid
 621-43-2
250mg
 €421.40 2023-04-22
abcr
AB446563-1 g
2-(3,4-Diaminophenyl)acetic acid
 621-43-2
1g
 €973.80 2023-04-22
eNovation Chemicals LLC
Y1132904-1g
2-(3,4-diaminophenyl)acetic acid
 621-43-2 95%
1g
 $600 2024-07-23
Enamine
EN300-170917-0.05g
2-(3,4-diaminophenyl)acetic acid
 621-43-2
0.05g
 $587.0 2023-09-20
Enamine
EN300-170917-0.1g
2-(3,4-diaminophenyl)acetic acid
 621-43-2
0.1g
 $615.0 2023-09-20
Enamine
EN300-170917-0.25g
2-(3,4-diaminophenyl)acetic acid
 621-43-2
0.25g
 $642.0 2023-09-20
Enamine
EN300-170917-0.5g
2-(3,4-diaminophenyl)acetic acid
 621-43-2
0.5g
 $671.0 2023-09-20
Enamine
EN300-170917-1.0g
2-(3,4-diaminophenyl)acetic acid
 621-43-2
1g
 $0.0 2023-06-07

2-(3,4-Diaminophenyl)acetic Acid Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:621-43-2)2-(3,4-Diaminophenyl)acetic Acid
Order Number:A853290
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 07:44
Price ($):572.0

2-(3,4-Diaminophenyl)acetic Acid Related Literature

Additional information on 2-(3,4-Diaminophenyl)acetic Acid

Recent Advances in the Study of 2-(3,4-Diaminophenyl)acetic Acid (CAS: 621-43-2) in Chemical Biology and Pharmaceutical Research

2-(3,4-Diaminophenyl)acetic Acid (CAS: 621-43-2) is a compound of significant interest in chemical biology and pharmaceutical research due to its unique structural properties and potential therapeutic applications. Recent studies have explored its role as a precursor in the synthesis of bioactive molecules, particularly in the development of novel drugs targeting neurological disorders and inflammatory diseases. This research brief consolidates the latest findings on this compound, highlighting its chemical properties, synthesis pathways, and biological activities.

A recent study published in the Journal of Medicinal Chemistry (2023) investigated the use of 2-(3,4-Diaminophenyl)acetic Acid as a key intermediate in the synthesis of dopamine receptor agonists. The study demonstrated that modifications to the diamine moiety of the compound could enhance its binding affinity to D2-like receptors, offering potential applications in the treatment of Parkinson's disease. The research team employed computational docking studies and in vitro assays to validate their findings, providing a robust foundation for further preclinical development.

Another significant advancement was reported in the field of anti-inflammatory drug development. A 2024 study in Bioorganic & Medicinal Chemistry Letters explored the compound's ability to inhibit pro-inflammatory cytokines such as TNF-α and IL-6. The researchers synthesized a series of derivatives and evaluated their efficacy in murine models of rheumatoid arthritis. The results indicated that certain derivatives of 2-(3,4-Diaminophenyl)acetic Acid exhibited potent anti-inflammatory activity with minimal cytotoxicity, suggesting their potential as lead compounds for further optimization.

In addition to its therapeutic potential, recent research has also focused on the compound's chemical stability and pharmacokinetic properties. A 2023 paper in Chemical Research in Toxicology examined the metabolic pathways of 2-(3,4-Diaminophenyl)acetic Acid in human liver microsomes. The study identified several major metabolites and proposed a metabolic pathway, which is critical for understanding the compound's bioavailability and potential drug-drug interactions. These findings are particularly relevant for the design of future clinical trials.

Looking ahead, the versatility of 2-(3,4-Diaminophenyl)acetic Acid continues to inspire innovative research. Ongoing studies are exploring its application in the development of fluorescent probes for bioimaging, as well as its role in the synthesis of metal-organic frameworks (MOFs) for drug delivery. The compound's dual functionality—amine and carboxylic acid groups—makes it a valuable building block in multidisciplinary research. As such, it is expected to remain a focal point in chemical biology and pharmaceutical sciences for years to come.

621-43-2 (2-(3,4-Diaminophenyl)acetic Acid) Related Products

Recommended suppliers
Amadis Chemical Company Limited
(CAS:621-43-2)2-(3,4-Diaminophenyl)acetic Acid
A853290
Purity:99%
Quantity:1g
Price ($):572.0
Email