• 1. Examination of ammonia–poly(pyrrole) interactions by piezoelectric and conductivity measurements
  Analyst, 1991,116, 1125-1130
• 2. Establishing plasmon contribution to chemical reactions: alkoxyamines as a thermal probe?
  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
• 3. Enabling shape memory and healable effects in a conjugated polymer by incorporating siloxane via dynamic imine bond?
  Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
• 4. Dissolution of cork biopolymers in biocompatible ionic liquids
  Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
• 5. Estimating and correcting interference fringes in infrared spectra in infrared hyperspectral imaging
  Ghazal Azarfar,Ebrahim Aboualizadeh,Nicholas M. Walter,Simona Ratti,Camilla Olivieri,Alessandra Norici,Michael Nasse,Achim Kohler,Mario Giordano Analyst, 2018,143, 4674-4683

• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Aralkylamines
• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Amines Aralkylamines

Comprehensive Overview of Pyrimidin-4-ylmethanamine Dihydrochloride (CAS No. 618446-08-5): Properties, Applications, and Research Insights

Pyrimidin-4-ylmethanamine dihydrochloride (CAS No. 618446-08-5) is a specialized organic compound with significant relevance in pharmaceutical and biochemical research. This pyrimidine derivative is characterized by its unique molecular structure, featuring a pyrimidin-4-ylmethyl group bonded to an amine, which is further stabilized as a dihydrochloride salt. The compound's high purity and water solubility make it a valuable intermediate in drug discovery, particularly in the development of kinase inhibitors and antiviral agents.

In recent years, the demand for pyrimidine-based compounds has surged due to their role in targeting disease-related pathways, such as cancer and infectious diseases. Researchers frequently search for "Pyrimidin-4-ylmethanamine synthesis" or "618446-08-5 applications," reflecting its growing importance in medicinal chemistry. The compound's mechanism of action often involves modulating enzymatic activity, making it a focal point for studies on personalized medicine and precision therapeutics.

From a structural perspective, Pyrimidin-4-ylmethanamine dihydrochloride exhibits a crystalline solid form under standard conditions, with a molecular weight of 196.07 g/mol. Its stability in aqueous solutions allows for versatile use in high-throughput screening (HTS) assays, a technique widely adopted in modern drug discovery. Laboratories often inquire about "CAS 618446-08-5 solubility" or "storage conditions for pyrimidine derivatives," underscoring the need for precise handling protocols.

The compound's applications extend to bioconjugation and proteomics, where it serves as a linker or labeling reagent. Its amine functional group enables covalent bonding with carboxylic acids or other electrophiles, facilitating the design of targeted drug delivery systems. This aligns with the trending interest in "smart therapeutics" and "nanomedicine," as evidenced by search engine analytics.

Quality control of Pyrimidin-4-ylmethanamine dihydrochloride is critical, with analytical techniques like HPLC and NMR spectroscopy ensuring batch-to-batch consistency. Suppliers and researchers prioritize "618446-08-5 purity standards" and "pyrimidine derivative suppliers," highlighting the compound's niche yet expanding market. Regulatory compliance, such as REACH and GMP certifications, further validates its suitability for preclinical studies.

Emerging trends also link this compound to AI-driven drug discovery, where computational models predict its interactions with biological targets. Searches for "machine learning in pyrimidine optimization" or "CAS 618446-08-5 docking studies" reflect the intersection of chemistry and artificial intelligence. Such advancements accelerate the identification of novel therapeutic candidates while reducing R&D costs.

In summary, Pyrimidin-4-ylmethanamine dihydrochloride (CAS No. 618446-08-5) represents a versatile tool for researchers exploring small-molecule therapeutics. Its compatibility with cutting-edge technologies and alignment with global health priorities ensures its continued relevance in scientific innovation.

• 859628-54-9(4-(Aminomethyl)-6-methylpyrimidin-2-amine)
• 921091-02-3(N-Methyl-1-(2-methylpyrimidin-4-yl)methanamine dihydrochloride)
• 22454-79-1((2-methylpyrimidin-4-yl)methanamine)
• 181363-10-0((2-chloropyrimidin-4-yl)methanamine)
• 1138011-17-2(pyrimidin-4-ylmethanamine hydrochloride)
• 45588-79-2(pyrimidin-4-ylmethanamine)
• 179873-38-2(N-Methyl-1-pyrimidin-4-ylmethanamine dihydrochloride)
• 1390654-85-9((4-methyl-2-pyrimidinyl)methylamine dihydrochloride)
• 929973-95-5(4-(Aminomethyl)pyrimidin-2-amine)
• 1260783-69-4(N-methyl-1-pyrimidin-4-ylmethanamine;hydrochloride)