Cas no 617-04-9 (Methyl α-D-mannopyranoside)

Methyl α-D-mannopyranoside is a synthetic derivative of D-mannose, commonly used as a biochemical reagent in glycobiology research. Its stable α-anomeric configuration makes it valuable for studying carbohydrate-protein interactions, particularly in lectin binding assays and glycosidase inhibition studies. The compound serves as a competitive inhibitor for mannose-specific lectins, aiding in the investigation of cell-surface recognition processes. Its high purity and well-defined structure ensure reproducibility in experimental applications. Methyl α-D-mannopyranoside is also employed as a precursor in the synthesis of more complex glycoconjugates. The product is typically supplied as a white crystalline powder, soluble in water and polar organic solvents, ensuring compatibility with a range of biochemical protocols.
Methyl α-D-mannopyranoside structure
Methyl α-D-mannopyranoside structure
Product Name:Methyl α-D-mannopyranoside
CAS No:617-04-9
MF:C7H14O6
MW:194.182463169098
MDL:MFCD00063262
CID:82741
PubChem ID:24897124
Update Time:2025-10-29

Methyl α-D-mannopyranoside Chemical and Physical Properties

Names and Identifiers

    • Methyl-alpha-D-mannopyranoside
    • Methyl alpha-D-Mannopyranoside
    • Methyl α-D-mannopyranoside
    • alpha-Methyl-D-mannopyranoside
    • Methyl .α.-D-mannopyranoside
    • Methyl α-D-Mannopyra
    • Methyl-a-D-mannopyranoside
    • METHYL-a-D-MANNOPYRANOSIDE(RG)
    • Methyl-α-D-mannopyranoside
    • 1-O-Methyl-α-D-mannopyranoside
    • Mannopyranoside, methyl, α-D-
    • Methyl α-D-mannoside
    • NSC 1225
    • α-D-Mannopyranoside, methyl
    • α-D-Methyl mannoside
    • α-Methyl-D-Mannopyranoside
    • α-Methyl-D-mannoside
    • Methyl a-D-mannopyranoside
    • Methyl alpha-D-mannoside
    • alpha-Methyl-D-mannoside
    • alpha-Methyl mannopyranoside
    • 1-O-Methyl-alpha-D-mannopyranoside
    • O1-Methyl-Mannose
    • alpha-D-Methyl mannoside
    • Methyl-alpha-D-mannoside
    • alpha-Methyl-D-(-)-mannoside
    • HOVAGTYPODGVJG-VEIUFWFVSA-N
    • (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol
    • .alpha.-D
    • Methyl-α-D-mannose
    • Methyl α-D-mannopyranoside,α-Methyl D-mannoside
    • Methyl α-D-maopyranoside
    • alpha-Methyl-D-mannoside Methyl alpha-D-Mannoside
    • Methyl α-D-mannopyranoside Supplement
    • Methyl-α-D-mannopyranoside≥ 99% (Assay)
    • .alpha.-D-Mannopyranoside, methyl
    • Methylmannoside
    • Methyl alpha-D-mannoside (VAN)
    • -;Methyl alpha-D-mannopyranoside
    • MFCD00063262
    • Methyl .alpha.-D-mannoside
    • Mannopyranoside, methyl, alpha-D-
    • CS-0098154
    • Mannopyranoside, methyl, .alpha.-D-
    • AKOS016010476
    • (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-methoxy-tetrahydropyran-3,4,5-triol
    • CCG-53954
    • Methyl .alpha.-D-mannopyranoside
    • Methyl alpha-D-mannopyranoside, >=99% (GC)
    • CHEBI:43943
    • AS-58701
    • NS00069872
    • CHEMBL195368
    • 2jdy
    • 1-O-Methyl-.alpha.-D-mannopyranoside
    • F16319
    • Methyl-alphaD-mannopyranoside
    • methyl -d-mannopyranoside
    • 1ws5
    • .alpha.-Methyl-D-mannopyranoside
    • DTXSID10897266
    • alpha-D-Mannopyranoside, methyl
    • a-Methyl D-mannoside
    • s5047
    • NSC 224429
    • 25281-48-5
    • EINECS 210-502-3
    • AMY31295
    • methyl
    • a-methyl-D-mannoside
    • Epitope ID:145662
    • C7H14O6
    • 617-04-9
    • A868645
    • Q27093072
    • .alpha.-Methyl-D-mannoside
    • HY-W039897
    • A-d-mannopyranoside
    • .alpha.-D-Methyl mannoside
    • O1-METHYL-MANNOSE; methyl alpha-D-mannoside; methyl D-mannoside; methyl mannoside
    • 2jdn
    • SCHEMBL136446
    • (2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-methoxyoxane-3,4,5-triol
    • METHYL ?-D-MANNOSIDE
    • M0368
    • Methyl-.alpha.-D-mannopyranoside
    • DB01979
    • 35B8275C-EB56-4981-81A0-8E358215B1A9
    • 2bv4
    • Methyl alpha-D-mannopyranoside, for microbiology, >=99.0%
    • BDBM50166886
    • alpha-Methyl D-mannoside
    • SR-01000643077-1
    • Mannopyranoside, methyl, alphaD
    • Methyl alphaDmannoside
    • 1-O-Methyl-a-D-mannopyranoside
    • Methyl-I+--D-mannoside
    • alpha-Methylmannose
    • alphaDMannopyranoside, methyl
    • Methyl alphaDmannoside (VAN)
    • Methylmannoside, alpha-D-isomer
    • alphaMethyl mannopyranoside
    • alpha-Methylmannoside
    • Mannopyranoside, methyl, alphaD (8CI)
    • methyl a-d-mannoside
    • alphaDMethyl mannoside
    • beta-Methylmannoside
    • Methyl mannoside, (alpha-D)-isomer
    • DA-65396
    • 1OMethylalphaDmannopyranoside
    • alphaMethylD()mannoside
    • methyl-a-d-mannoside
    • Methyl I+--D-mannoside
    • alphaMethylDmannopyranoside
    • a-Methyl mannopyranoside
    • alpha-methyl-D-mannose
    • DTXCID401326649
    • 1-O-Methyl-I+--D-mannopyranoside
    • MDL: MFCD00063262
    • Inchi: 1S/C7H14O6/c1-12-7-6(11)5(10)4(9)3(2-8)13-7/h3-11H,2H2,1H3/t3-,4-,5+,6+,7+/m1/s1
    • InChI Key: HOVAGTYPODGVJG-VEIUFWFVSA-N
    • SMILES: O1[C@@H]([C@H]([C@H]([C@@H]([C@H]1CO)O)O)O)OC
    • BRN: 81566

Computed Properties

  • Exact Mass: 194.07902
  • Monoisotopic Mass: 194.079
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 4
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 2
  • Complexity: 163
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 5
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • XLogP3: -2.2
  • Topological Polar Surface Area: 99.4

Experimental Properties

  • Color/Form: White powder
  • Density: 1.2501 (rough estimate)
  • Melting Point: 192.0 to 196.0 deg-C
  • Boiling Point: 418.236°C at 760 mmHg
  • Flash Point: 189.1oC
  • Refractive Index: 79.5 ° (C=4, H2O)
  • Solubility: H2O: 0.1?g/mL, clear
  • Water Partition Coefficient: It is easily soluble in methanol, water. Insoluble in ether.
  • PSA: 99.38
  • LogP: -2.56730

Methyl α-D-mannopyranoside Security Information

  • Signal Word:Warning
  • Hazard Statement: H302-H315-H319-H335
  • Warning Statement: P261-P305+P351+P338
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 10
  • Safety Instruction: S22;S24/25
  • FLUKA BRAND F CODES:3-10
  • Hazardous Material Identification: Xi
  • Storage Condition:Sealed in dry,2-8°C
  • Safety Term:S22-S24/25

Methyl α-D-mannopyranoside Pricemore >>

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Methyl α-D-mannopyranoside Suppliers

Amadis Chemical Company Limited
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(CAS:617-04-9)Methyl α-D-mannopyranoside
Order Number:A868645
Stock Status:in Stock
Quantity:1kg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 09:13
Price ($):177.0
Suzhou Senfeida Chemical Co., Ltd
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(CAS:617-04-9)METHYL-ALPHA-D-MANNOPYRANOSIDE
Order Number:sfd20694
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:38
Price ($):discuss personally
Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:617-04-9)Methylα-D-mannopyranoside
Order Number:LE11796;LE1695357
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:05
Price ($):discuss personally

Methyl α-D-mannopyranoside Related Literature

Additional information on Methyl α-D-mannopyranoside

Methyl α-D-mannopyranoside (CAS 617-04-9): Properties, Applications, and Research Insights

Methyl α-D-mannopyranoside (CAS 617-04-9) is a specialized carbohydrate derivative widely used in biochemical research and pharmaceutical applications. This compound, a methyl glycoside of α-D-mannose, serves as a crucial tool in studying carbohydrate-protein interactions, particularly in lectin binding studies. With the growing interest in glycobiology and immunology, methyl mannopyranoside derivatives have gained significant attention in recent scientific literature.

The molecular structure of Methyl α-D-mannopyranoside features a pyranose ring with specific stereochemistry that makes it valuable for investigating molecular recognition processes. Researchers frequently utilize this compound as a competitive inhibitor in studies involving mannose-binding proteins, which play essential roles in immune system function and pathogen recognition. Current trends in glycoscience research highlight the importance of such compounds in developing novel therapeutic approaches for immune-related disorders.

In pharmaceutical applications, Methyl α-D-mannopyranoside serves as a building block for more complex carbohydrate structures. Its stability and well-defined configuration make it particularly useful in glycoconjugate synthesis, an area experiencing rapid growth due to advances in vaccine development and targeted drug delivery systems. The compound's ability to mimic natural carbohydrate epitopes has positioned it as a valuable tool in immunological research and drug discovery programs.

The production and purification of Methyl α-D-mannopyranoside follow stringent quality control measures to ensure high purity levels required for research applications. Analytical techniques such as HPLC analysis and mass spectrometry are routinely employed to verify the compound's identity and purity. These quality assurance practices align with current Good Manufacturing Practice (cGMP) standards when the material is intended for preclinical or diagnostic use.

Recent advancements in carbohydrate chemistry have expanded the utility of methyl glycosides like Methyl α-D-mannopyranoside in various fields. In material science, these compounds contribute to the development of biocompatible surfaces with specific molecular recognition properties. The growing field of glyconanotechnology utilizes such molecules to create functional nanomaterials with applications in biosensing and medical diagnostics.

Storage and handling of Methyl α-D-mannopyranoside require standard laboratory precautions for carbohydrate compounds. The material typically appears as a white crystalline powder with good stability under recommended storage conditions. Proper documentation and labeling according to chemical safety standards ensure safe laboratory use while maintaining research reproducibility.

The market for specialized carbohydrates like Methyl α-D-mannopyranoside continues to grow, driven by increasing research in glycobiology and immunotherapeutics. Suppliers offer various quantities ranging from milligram-scale for research laboratories to kilogram quantities for industrial applications. Pricing reflects the compound's purity grade, with high-purity methyl α-D-mannopyranoside commanding premium prices in the research chemicals market.

Ongoing research explores novel applications of Methyl α-D-mannopyranoside in areas such as antiviral drug development and cancer immunotherapy. The compound's ability to interfere with pathogen adhesion mechanisms makes it particularly interesting for developing broad-spectrum antimicrobial strategies. These developments align with current global health priorities and the search for new therapeutic modalities against emerging infectious diseases.

Quality control specifications for Methyl α-D-mannopyranoside typically include parameters such as melting point range, optical rotation values, and chromatographic purity. Analytical certificates provided with research-grade material document these characteristics, ensuring researchers can rely on consistent performance in their experiments. The availability of certified reference standards further supports the compound's use in quantitative applications.

As the scientific community continues to unravel the complexities of carbohydrate-mediated biological processes, compounds like Methyl α-D-mannopyranoside will remain essential research tools. The intersection of glycoscience with emerging technologies such as artificial intelligence in drug discovery and precision medicine promises to unlock new applications for these molecular building blocks in the coming years.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:617-04-9)Methyl α-D-mannopyranoside
A868645
Purity:99%
Quantity:1kg
Price ($):177.0
Email
Suzhou Senfeida Chemical Co., Ltd
(CAS:617-04-9)METHYL-ALPHA-D-MANNOPYRANOSIDE
sfd20694
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email