• 1. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 2. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
  Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
• 3. Evidence of pre-micellar aggregates in aqueous solution of amphiphilic PDMS–PEO block copolymer?
  Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
• 4. Exchanged ligands on the surface of a giant cluster: [(MoO3)176(H2O)63(CH3OH)17Hn](32 – n)–
  Chem. Commun., 1998, 1501-1502
• 5. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Organic carbonic acids and derivatives Ureas

Comprehensive Overview of (Cyclopropylmethyl)urea (CAS No. 61600-98-4): Properties, Applications, and Research Insights

(Cyclopropylmethyl)urea (CAS No. 61600-98-4) is a specialized organic compound featuring a cyclopropylmethyl group attached to a urea moiety. This unique structure grants it distinct chemical and biological properties, making it a subject of interest in pharmaceutical, agrochemical, and material science research. The compound’s molecular formula (C₅H₁₀N₂O) and molecular weight (114.15 g/mol) are critical for its characterization and application in synthetic chemistry. Researchers often explore its hydrogen-bonding capacity and solubility profile, which are pivotal for drug design and formulation.

In recent years, the demand for cyclopropyl-containing compounds like (cyclopropylmethyl)urea has surged due to their role in modulating bioactivity and metabolic stability. This aligns with the growing trend of small-molecule drug discovery, where urea derivatives are leveraged for their ability to interact with biological targets. A common search query, such as "urea derivatives in medicinal chemistry", reflects this interest. The compound’s CAS No. 61600-98-4 is frequently cited in patents and academic papers, underscoring its relevance in structure-activity relationship (SAR) studies.

From a synthetic perspective, (cyclopropylmethyl)urea is often prepared via the reaction of cyclopropylmethylamine with urea or its equivalents. Its thermal stability and crystallinity are key parameters for industrial-scale production. Users searching for "synthesis of cyclopropylmethyl urea" or "CAS 61600-98-4 suppliers" typically seek practical insights into its commercial availability and lab-scale preparation. Notably, the compound’s melting point and NMR spectra are well-documented, aiding in quality control and analytical validation.

Beyond pharmaceuticals, (cyclopropylmethyl)urea has potential applications in agrochemicals, particularly as a precursor for herbicides and plant growth regulators. The cyclopropyl ring is known to enhance the lipophilicity and environmental persistence of such compounds, a topic often explored under search terms like "urea-based agrochemicals". Environmental scientists also investigate its degradation pathways to ensure compliance with green chemistry principles.

In material science, urea derivatives like CAS No. 61600-98-4 are studied for their self-assembly properties and potential use in supramolecular chemistry. The compound’s ability to form hydrogen-bonded networks makes it a candidate for designing functional materials, such as molecular sensors or porous frameworks. Queries like "urea in nanotechnology" highlight this interdisciplinary appeal.

Safety and handling of (cyclopropylmethyl)urea are governed by standard laboratory protocols. While not classified as hazardous, its MSDS (Material Safety Data Sheet) recommends proper personal protective equipment (PPE) during handling. This aligns with the broader industry focus on safe chemical practices, a recurring theme in searches like "urea derivative safety guidelines".

In conclusion, (cyclopropylmethyl)urea (CAS No. 61600-98-4) exemplifies the versatility of urea-based compounds in modern science. Its applications span drug development, agriculture, and advanced materials, driven by its tunable properties and structural simplicity. As research continues, this compound will likely remain a focal point for innovations in organic synthesis and applied chemistry.

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