• 1. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
  Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
• 2. Fe(iii)-mediated isomerization of α,α-diarylallylic alcohols to ketones via radical 1,2-aryl migration?
  Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
• 3. Dissolution of cork biopolymers in biocompatible ionic liquids
  Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
• 4. Evolution of important glucosinolates in three common Brassica vegetables during their processing into vegetable powder and in vitro gastric digestion
  Nan Fu,Naphaporn Chiewchan,Xiao Dong Chen Food Funct., 2020,11, 211-220
• 5. Enabling shape memory and healable effects in a conjugated polymer by incorporating siloxane via dynamic imine bond?
  Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095

• Solvents and Organic Chemicals Organic Compounds Benzenoids Indanes Indanes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Indanes

4-Bromo-2,3-Dihydro-1H-Indene: A Comprehensive Overview

4-Bromo-2,3-dihydro-1H-indene, also known by its CAS number CAS No. 6134-53-8, is a fascinating organic compound with a unique structure and a wide range of applications in various fields. This compound belongs to the class of indenes, which are bicyclic aromatic hydrocarbons with a five-membered ring fused to a three-membered ring. The presence of a bromine atom at the fourth position of the indene skeleton adds distinct chemical properties, making it an interesting subject for both academic and industrial research.

The synthesis of 4-bromo-2,3-dihydro-1H-indene has been extensively studied, with researchers exploring various methods to optimize its production. One of the most common approaches involves the bromination of indene derivatives using bromine in the presence of a catalyst. Recent studies have focused on improving the yield and purity of the compound by employing novel catalysts and reaction conditions. For instance, the use of microwave-assisted synthesis has been shown to significantly reduce reaction times while maintaining high product quality.

In terms of physical and chemical properties, 4-bromo-2,3-dihydro-1H-indene exhibits a melting point of approximately 70°C and a boiling point around 200°C under standard conditions. Its solubility in common organic solvents such as dichloromethane and ethyl acetate makes it suitable for various chemical reactions. The compound is also known for its moderate stability under normal storage conditions, though it is recommended to keep it away from strong oxidizing agents to prevent degradation.

The applications of 4-bromo-2,3-dihydro-1H-indene span across multiple industries. In the pharmaceutical sector, it serves as an intermediate in the synthesis of complex molecules with potential therapeutic properties. For example, recent research has highlighted its role in the development of anti-inflammatory agents and antioxidants. Additionally, this compound is utilized in the electronics industry as a precursor for advanced materials such as organic light-emitting diodes (OLEDs) and semiconductors.

In recent years, there has been growing interest in understanding the environmental impact of 4-bromo-2,3-dihydro-1H-indene. Studies have shown that while it is not inherently hazardous under normal conditions, improper disposal or exposure to high temperatures can lead to the release of toxic byproducts. To address this concern, researchers are exploring eco-friendly synthesis methods and recycling strategies to minimize environmental footprint.

From a toxicological perspective, 4-bromo-2,3-dihydro-1H-indene has been subjected to various safety assessments. Acute toxicity studies indicate that it is relatively low in toxicity when handled appropriately. However, prolonged exposure or ingestion may cause adverse effects, particularly on the respiratory and digestive systems. Regulatory bodies have established guidelines for safe handling and storage to ensure worker safety and environmental protection.

The future outlook for 4-bromo-2,3-dihydro-1H-indene appears promising, with ongoing research focusing on expanding its applications and improving its production efficiency. Collaborative efforts between academia and industry are expected to yield innovative solutions that further enhance its utility across diverse sectors.

• 881405-54-5(1H-BENZ[E]INDENE, 4-BROMO-2,3,6,7,8,9-HEXAHYDRO-1-METHYL-)
• 881410-90-8(1H-INDENE, 4-BROMO-2,3-DIHYDRO-2,2,5,7-TETRAMETHYL-)
• 88632-74-0(1H-Indene, 4-bromo-2,3-dihydro-5,7-dimethyl-)
• 88632-73-9(1H-Indene, 5-bromo-2,3-dihydro-4,7-dimethyl-)
• 88727-95-1(1H-Indene, 5-bromo-2,3-dihydro-4,6-dimethyl-)
• 64735-73-5(NAPHTHALENE, 5,7-DIBROMO-1,2,3,4-TETRAHYDRO-)
• 75252-57-2(2,9-ETHANODIBENZO[A,E]CYCLOOCTENE, 3-BROMO-5,6,11,12-TETRAHYDRO-)
• 881405-51-2(AS-INDACENE, 4-BROMO-1,2,3,6,7,8-HEXAHYDRO-1-METHYL-)
• 148743-64-0(ANTHRACENE, 9,10-DIBROMO-1,2,3,4,5,6,7,8-OCTAHYDRO-)
• 6134-55-0(5-Bromo-1,2,3,4-tetrahydronaphthalene)