Cas no 61323-24-8 (2-Isobutyl-4-methylthiazole)

2-Isobutyl-4-methylthiazole is a heterocyclic organic compound belonging to the thiazole class, characterized by its distinct sulfur and nitrogen-containing ring structure. This compound is widely utilized in the flavor and fragrance industry due to its potent, green, and slightly metallic odor profile, often employed to impart natural nuances in food and cosmetic applications. Its stability under typical processing conditions and compatibility with various formulations make it a reliable choice for synthetic flavor compositions. Additionally, its well-defined chemical properties ensure consistent performance in both industrial and laboratory settings. The compound's purity and structural specificity further enhance its utility in precision-driven applications.
2-Isobutyl-4-methylthiazole structure
2-Isobutyl-4-methylthiazole structure
Product Name:2-Isobutyl-4-methylthiazole
CAS No:61323-24-8
MF:C8H13NS
MW:155.26052069664
MDL:MFCD00053138
CID:57673
PubChem ID:87571794
Update Time:2026-05-14

2-Isobutyl-4-methylthiazole Chemical and Physical Properties

Names and Identifiers

    • 2-Isobutyl-4-methylthiazole
    • 2-Isobutyl-4-mezhylthiazole
    • 2-Isobutyl-5-methylthiazole
    • 4-methyl-2-(2-methylpropyl)-1,3-thiazole
    • 4-Methyl-2-(2-methylpropyl)thiazole
    • MDL: MFCD00053138
    • Inchi: InChI=1S/C8H13NS/c1-6(2)4-8-9-7(3)5-10-8/h5-6H,4H2,1-3H3
    • InChI Key: JBUCYVMFLWLDIO-UHFFFAOYSA-N
    • SMILES: CC(C)CC1=NC(=CS1)C

Computed Properties

  • Exact Mass: 155.07700
  • Monoisotopic Mass: 155.07687
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 2
  • Complexity: 103
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 2
  • XLogP3: 3
  • Topological Polar Surface Area: 41.1

Experimental Properties

  • Color/Form: Not determined
  • Density: 0.979
  • Boiling Point: 189°C(lit.)
  • Flash Point: 74.5°C
  • Refractive Index: 1.4930-1.4950
  • PSA: 41.13000
  • LogP: 2.65000

2-Isobutyl-4-methylthiazole Security Information

2-Isobutyl-4-methylthiazole Customs Data

  • HS CODE:2934100090
  • Customs Data:

    China Customs Code:

    2934100090

    Overview:

    2934100090. Compounds that structurally contain a non fused thiazole ring(Whether hydrogenated or not). VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

2-Isobutyl-4-methylthiazole Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Fluorochem
226548-5ml
2-Isobutyl-4-methylthiazole
61323-24-8 95%
5ml
£69.00 2022-02-28
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
I157519-100g
2-Isobutyl-4-methylthiazole
61323-24-8 >96.0%(GC)
100g
¥485.90 2023-09-02
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
I157519-25g
2-Isobutyl-4-methylthiazole
61323-24-8 >96.0%(GC)
25g
¥146.90 2023-09-02
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
I157519-5g
2-Isobutyl-4-methylthiazole
61323-24-8 >96.0%(GC)
5g
¥389.90 2023-09-02
Alichem
A059003304-25g
2-Isobutyl-4-methylthiazole
61323-24-8 97%
25g
$207.10 2023-09-01
Alichem
A059003304-100g
2-Isobutyl-4-methylthiazole
61323-24-8 97%
100g
$565.60 2023-09-01
TRC
B448830-50mg
2-Isobutyl-4-methylthiazole
61323-24-8
50mg
$ 50.00 2022-06-07
TRC
B448830-100mg
2-Isobutyl-4-methylthiazole
61323-24-8
100mg
$ 65.00 2022-06-07
TRC
B448830-500mg
2-Isobutyl-4-methylthiazole
61323-24-8
500mg
$ 95.00 2022-06-07
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
I858786-5g
2-Isobutyl-4-Methylthiazole
61323-24-8 ≥98%
5g
339.30 2021-05-17

Additional information on 2-Isobutyl-4-methylthiazole

Professional Introduction to 2-Isobutyl-4-methylthiazole (CAS No. 61323-24-8)

2-Isobutyl-4-methylthiazole, identified by the chemical abstracts service number 61323-24-8, is a heterocyclic compound that has garnered significant attention in the field of pharmaceutical and agrochemical research due to its versatile structural properties and potential biological activities. This compound belongs to the thiazole class, a family of sulfur-containing heterocycles that are widely recognized for their role in medicinal chemistry. The presence of both an isobutyl group and a methyl group in its structure contributes to its unique chemical reactivity and functionalization possibilities, making it a valuable scaffold for the development of novel bioactive molecules.

The structural framework of 2-Isobutyl-4-methylthiazole consists of a five-membered ring containing sulfur and nitrogen atoms, with an isobutyl substituent at the 2-position and a methyl group at the 4-position. This arrangement imparts distinct electronic and steric properties to the molecule, which can be exploited in drug design. The thiazole core is known to exhibit various pharmacological effects, including antimicrobial, antifungal, anti-inflammatory, and anticancer activities. These properties have been extensively studied in academic and industrial research settings, leading to the identification of several thiazole derivatives with promising therapeutic potential.

In recent years, there has been a surge in research focused on developing new thiazole-based compounds for medicinal applications. One particularly notable area of investigation has been the exploration of 2-Isobutyl-4-methylthiazole as a precursor for synthesizing novel antimicrobial agents. The compound's ability to interact with biological targets such as bacterial enzymes and cell membranes has been investigated in detail. For instance, studies have shown that derivatives of 2-Isobutyl-4-methylthiazole can disrupt bacterial cell wall synthesis, leading to their efficacy against resistant strains of pathogens. This has opened up new avenues for combating multidrug-resistant infections, a critical challenge in modern medicine.

Moreover, the agrochemical industry has also recognized the potential of 2-Isobutyl-4-methylthiazole as a lead compound for developing novel pesticides and herbicides. The compound's structural features allow it to interact with biological pathways in pests and weeds, thereby offering effective control measures. Research has demonstrated that certain derivatives of this molecule can inhibit key enzymes involved in plant growth regulation, making them promising candidates for use in sustainable agriculture. The development of such environmentally friendly agrochemicals is crucial for ensuring food security while minimizing ecological impact.

The synthesis of 2-Isobutyl-4-methylthiazole typically involves multi-step organic reactions, often starting from commercially available precursors such as thiourea and butanone or isobutyraldehyde. The process generally involves cyclization reactions followed by functional group transformations to introduce the desired substituents. Advances in synthetic methodologies have enabled more efficient and scalable production of this compound, facilitating its use in both academic research and industrial applications. The availability of high-purity 2-Isobutyl-4-methylthiazole (CAS No. 61323-24-8) from reputable suppliers ensures that researchers can conduct rigorous investigations without compromising on quality.

One of the most exciting developments in the study of 2-Isobutyl-4-methylthiazole has been its incorporation into drug discovery programs targeting neurological disorders. Thiazole derivatives have shown promise in modulating neurotransmitter systems, making them potential candidates for treating conditions such as Alzheimer's disease, Parkinson's disease, and epilepsy. Preclinical studies have indicated that certain analogs of this compound can cross the blood-brain barrier and exert neuroprotective effects by inhibiting oxidative stress and inflammation. These findings have spurred further investigation into optimizing the pharmacological properties of 2-Isobutyl-4-methylthiazole derivatives for therapeutic use.

The chemical reactivity of 2-Isobutyl-4-methylthiazole also makes it an attractive scaffold for developing probes in chemical biology research. Researchers have utilized this compound to study enzyme mechanisms and cellular processes by designing fluorescent or affinity-tagged derivatives. Such probes can provide insights into complex biological pathways, aiding in the discovery of new drug targets and therapeutic strategies. The versatility of 2-Isobutyl-4-methylthiazole as a chemical tool underscores its importance not only as a potential drug candidate but also as a valuable intermediate in synthetic chemistry.

In conclusion, 2-Isobutyl-4-methylthiazole (CAS No. 61323-24-8) represents a fascinating compound with broad applications across multiple domains of science and industry. Its unique structural features have positioned it as a key player in pharmaceutical research, agrochemical development, and chemical biology investigations. As our understanding of its properties continues to evolve, so too will its potential contributions to advancing human health and sustainable agriculture. The ongoing exploration of this molecule highlights its significance as a cornerstone in modern chemical research.

Recommended suppliers
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Shanghai Bent Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangxi Boyang Pharmaceutical Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangxi Boyang Pharmaceutical Chemical Co., Ltd
Wuhan Comings Biotechnology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Wuhan Comings Biotechnology Co., Ltd.
SunaTech Inc.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
SunaTech Inc.