Cas no 60838-50-8 (3-Methoxyacrylonitrile)

3-Methoxyacrylonitrile is a versatile chemical intermediate characterized by its reactive acrylonitrile moiety and methoxy functional group. This compound is primarily utilized in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and specialty polymers. Its key advantages include high reactivity in Michael addition and polymerization reactions, enabling efficient derivatization and copolymerization. The methoxy group enhances solubility in polar solvents, facilitating its use in homogeneous reaction systems. Additionally, its stable yet reactive nature makes it suitable for controlled synthetic applications. Proper handling is required due to its potential toxicity and flammability. The compound is typically stored under inert conditions to maintain stability.
3-Methoxyacrylonitrile structure
3-Methoxyacrylonitrile structure
Product Name:3-Methoxyacrylonitrile
CAS No:60838-50-8
MF:C4H5NO
MW:83.0886008739471
MDL:MFCD00044798
CID:57606
PubChem ID:24862305
Update Time:2025-08-05

3-Methoxyacrylonitrile Chemical and Physical Properties

Names and Identifiers

    • 3-Methoxyacrylonitrile mixture of cis andtrans
    • 3-Methoxy-2-propenenitrile
    • 3-Methoxyacrylonitrile
    • (E)-3-methoxyprop-2-enenitrile
    • 3-Methoxyacrylonitrile (cis- and trans- Mixture)
    • IPCRTSDORDQHRO-DUXPYHPUSA-N
    • (E)-3-methoxyacrylonitrile
    • 3-methoxyprop-2-enenitrile
    • MFCD00044798
    • NS00122301
    • 60838-50-8
    • F16426
    • A832917
    • EN300-36430
    • trans-3-methoxyacrylonitrile
    • AKOS009158154
    • (E)-3-methoxy-2-propenenitrile
    • InChI=1/C4H5NO/c1-6-4-2-3-5/h2,4H,1H3/b4-2
    • MDL: MFCD00044798
    • Inchi: 1S/C4H5NO/c1-6-4-2-3-5/h2,4H,1H3/b4-2+
    • InChI Key: IPCRTSDORDQHRO-DUXPYHPUSA-N
    • SMILES: O(/C=C/C#N)C

Computed Properties

  • Exact Mass: 83.03710
  • Monoisotopic Mass: 83.037
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 6
  • Rotatable Bond Count: 1
  • Complexity: 87
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 33A^2
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 0.2

Experimental Properties

  • Color/Form: Not determined
  • Density: 0.99?g/mL?at 25?°C(lit.)
  • Melting Point: 76°C
  • Boiling Point: 189 oC
  • Flash Point: Fahrenheit: 168.8 ° f < br / > Celsius: 76 ° C < br / >
  • Refractive Index: n20/D 1.455(lit.)
  • PSA: 33.02000
  • LogP: 0.67008
  • Vapor Pressure: 1.0±0.3 mmHg at 25°C

3-Methoxyacrylonitrile Security Information

3-Methoxyacrylonitrile Customs Data

  • HS CODE:2926909090
  • Customs Data:

    China Customs Code:

    2926909090

    Overview:

    2926909090 Other nitrile based compounds. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

3-Methoxyacrylonitrile Pricemore >>

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3-Methoxyacrylonitrile Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:60838-50-8)3-Methoxyacrylonitrile
Order Number:A832917
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 15:30
Price ($):334.0

Additional information on 3-Methoxyacrylonitrile

3-Methoxyacrylonitrile (CAS No. 60838-50-8): Properties, Applications, and Market Insights

3-Methoxyacrylonitrile (CAS No. 60838-50-8) is a versatile organic compound with significant applications in various industries. This methoxy-substituted acrylonitrile derivative is known for its unique chemical properties, making it valuable in synthetic chemistry, pharmaceuticals, and specialty materials. Its molecular formula, C4H5NO, and structural features contribute to its reactivity and utility in diverse reactions.

The compound is characterized by its clear to pale yellow liquid appearance and a distinctive odor. With a molecular weight of 83.09 g/mol, 3-Methoxyacrylonitrile exhibits moderate solubility in organic solvents while being sparingly soluble in water. These physical properties make it suitable for various industrial processes where controlled reactivity is required.

One of the most important chemical properties of 3-Methoxyacrylonitrile is its ability to participate in Michael addition reactions. This characteristic makes it particularly valuable in the synthesis of complex organic molecules. Researchers frequently utilize this compound as a building block in the preparation of heterocyclic compounds, which are essential in pharmaceutical development.

In the pharmaceutical industry, 3-Methoxyacrylonitrile CAS 60838-50-8 serves as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its structural features allow for the introduction of methoxy and nitrile functional groups into target molecules, enabling the creation of compounds with specific biological activities. Recent studies have explored its potential in developing novel therapeutic agents, particularly in areas such as anti-inflammatory and antimicrobial applications.

The material science sector has also found applications for 3-methoxy substituted acrylonitrile. It functions as a monomer or co-monomer in the production of specialty polymers with enhanced properties. These polymers may exhibit improved thermal stability, chemical resistance, or specific optical characteristics, depending on the formulation and polymerization conditions.

Recent advancements in green chemistry have sparked interest in 3-Methoxyacrylonitrile as researchers explore more sustainable synthetic pathways. The compound's potential in atom-economical reactions and its role in developing environmentally friendly processes align with current industry trends toward sustainable chemical production. This aspect has become particularly relevant as manufacturers seek to reduce environmental impact while maintaining product quality.

Analytical characterization of 3-Methoxyacrylonitrile 60838-50-8 typically involves techniques such as gas chromatography (GC), high-performance liquid chromatography (HPLC), and nuclear magnetic resonance (NMR) spectroscopy. These methods ensure product purity and quality control, which are critical for applications in sensitive industries like pharmaceuticals and electronics.

From a commercial perspective, the global market for methoxyacrylonitrile derivatives has shown steady growth, driven by increasing demand from end-use industries. Manufacturers and suppliers continue to optimize production processes to meet the rising need for high-purity 3-Methoxyacrylonitrile, particularly in regions with strong pharmaceutical and specialty chemical sectors.

Handling and storage of 3-Methoxyacrylonitrile require standard chemical safety precautions. Proper ventilation, personal protective equipment, and appropriate containment measures should be implemented when working with this compound. While not classified as highly hazardous, prudent laboratory practices should always be followed to ensure safe usage.

Research into novel applications of 3-Methoxyacrylonitrile CAS No. 60838-50-8 continues to expand. Recent publications have investigated its potential in organic electronics, where its electron-withdrawing properties may contribute to the development of advanced materials for optoelectronic devices. This aligns with growing interest in organic semiconductors and conductive polymers.

The synthesis of 3-Methoxyacrylonitrile typically involves the reaction of appropriate precursors under controlled conditions. Process optimization remains an active area of research, with scientists exploring catalytic systems and reaction conditions that improve yield and selectivity while reducing energy consumption and waste generation.

Quality specifications for commercial 3-Methoxyacrylonitrile 60838-50-8 vary depending on intended use. Pharmaceutical-grade material typically requires higher purity levels (≥98%) with strict limits on impurities, while industrial-grade material may have slightly different specifications. Reputable suppliers provide comprehensive certificates of analysis to verify product quality.

Future prospects for 3-Methoxyacrylonitrile appear promising, with potential applications emerging in areas such as agrochemicals, advanced materials, and specialty coatings. As synthetic methodologies advance and new functional materials are developed, the demand for this versatile building block is expected to grow accordingly.

For researchers and industrial users seeking information about 3-Methoxyacrylonitrile properties or 60838-50-8 applications, consulting technical datasheets and recent scientific literature is recommended. The compound's unique combination of reactivity and stability continues to make it a valuable tool in synthetic chemistry and materials science.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:60838-50-8)3-Methoxyacrylonitrile
A832917
Purity:99%
Quantity:1g
Price ($):334.0
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