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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

6061-13-8: A Comprehensive Overview of (2S,3S)-2-Amino-3-methylsuccinic acid

Introduction to (2S,3S)-2-Amino-3-methylsuccinic acid (CAS No. 6061-13-8)

(2S,3S)-2-Amino-3-methylsuccinic acid, identified by the CAS registry number 6061-13-8, is a significant compound in the field of organic chemistry and biochemistry. This compound, also referred to as L-(+)-aspartic acid derivative, has garnered attention due to its unique structural properties and diverse applications in various scientific domains.

Chemical Structure and Properties

The molecular structure of (2S,3S)-2-Amino-3-methylsuccinic acid consists of a four-carbon chain with two stereogenic centers at positions 2 and 3. The stereochemistry is defined as (S,S) configuration, which plays a crucial role in its biological activity and chemical reactivity. The compound contains an amino group (-NH?) at position 2 and a methyl group (-CH?) at position 3, making it a derivative of succinic acid with specific functional groups that enhance its versatility.

Synthesis and Production Methods

The synthesis of (2S,3S)-2-Amino-3-methylsuccinic acid involves advanced chemical processes, including asymmetric catalysis and enzymatic reactions. Recent advancements in stereochemical control have enabled the production of this compound with high optical purity, which is essential for its application in pharmaceuticals and nutraceuticals.

Biological Activity and Applications

(2S,3S)-2-Amino-3-methylsuccinic acid exhibits significant biological activity due to its ability to act as a precursor in various metabolic pathways. It has been extensively studied for its role in amino acid metabolism and its potential as a building block in peptide synthesis.

In the field of pharmacology, this compound has shown promise as an intermediate in drug development, particularly in the synthesis of bioactive molecules with specific stereochemical requirements. Its applications extend to the food industry as well, where it is used as a flavor enhancer and a precursor for umami taste compounds.

Recent Research Findings

Recent studies have explored the role of (2S,3S)-2-Amino-3-methylsuccinic acid in neurodegenerative diseases such as Alzheimer's disease. Research indicates that this compound may play a protective role against oxidative stress and neurotoxicity, making it a potential candidate for therapeutic interventions.

Additionally, advancements in biotechnology have enabled the microbial production of this compound through engineered strains of bacteria and yeast. These methods offer sustainable alternatives to traditional chemical synthesis, aligning with the growing demand for eco-friendly manufacturing processes.

Future Prospects and Conclusion

The future of (2S,3S)-2-Amino-3-methylsuccinic acid (CAS No. 6061-13-8) looks promising as researchers continue to uncover its potential applications across multiple disciplines. With ongoing advancements in synthetic methods and biological research, this compound is poised to play an increasingly important role in both academic research and industrial applications.

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