Cas no 606-38-2 (4-Acetamido-5-nitro-m-xylene)

4-Acetamido-5-nitro-m-xylene is a nitro-substituted aromatic compound featuring both acetamido and nitro functional groups on a meta-xylene backbone. This structure imparts unique reactivity, making it valuable as an intermediate in organic synthesis, particularly for the preparation of dyes, pharmaceuticals, and agrochemicals. The electron-withdrawing nitro group enhances electrophilic substitution potential, while the acetamido moiety offers opportunities for further functionalization. Its well-defined crystalline form ensures consistent purity and handling properties. The compound’s stability under standard conditions and compatibility with common solvents facilitate its use in multi-step synthetic processes. It is particularly suited for applications requiring precise control over substitution patterns in aromatic systems.

4-Acetamido-5-nitro-m-xylene structure

Product Name:4-Acetamido-5-nitro-m-xylene

CAS No:606-38-2

MF:C₁₀H₁₂N₂O₃

MW:208.213882446289

MDL:MFCD00157615

CID:523750

PubChem ID:220810

Update Time:2025-08-04

4-Acetamido-5-nitro-m-xylene Chemical and Physical Properties

Names and Identifiers

- Acetamide,N-(2,4-dimethyl-6-nitrophenyl)-
- 4-Acetamido-5-nitro-m-xylene
- N-(2,4-DIMETHYL-6-NITROPHENYL)ACETAMIDE
- Acetamide, N-(2,4-dimethyl-6-nitrophenyl)-
- NSC4159
- Cambridge id 5211945
- Oprea1_425762
- ARONIS023347
- PXXMBAOADHXJSE-UHFFFAOYSA-N
- 2,4-Dimethyl-6-nitro acetanilide
- STL068918
- 7154AJ
- KM0423
- 2',4'-Dimethyl-6'-nitroacetoanilide
- TRA0099464
- SY005893
- N-(4,6-
- SCHEMBL3635385
- DTXSID90277784
- N-(2,4-dimethyl-6-nitro-phenyl)-acetamide
- 606-38-2
- N-(2,4-DIMETHYL-6-NITRO-PHENYL)ACETAMIDE
- 2,4-DIME 6-NO2 ACETANILIDE
- AS-31360
- AKOS000504279
- DB-014237
- SB76815
- ALBB-025937
- AE-641/02616023
- MFCD00157615
- MDL： MFCD00157615
- Inchi： 1S/C10H12N2O3/c1-6-4-7(2)10(11-8(3)13)9(5-6)12(14)15/h4-5H,1-3H3,(H,11,13)
- InChI Key： PXXMBAOADHXJSE-UHFFFAOYSA-N
- SMILES： [O-][N+](C1=CC(C)=CC(C)=C1NC(C)=O)=O

Computed Properties

Exact Mass: 208.08500
Monoisotopic Mass: 208.085
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Heavy Atom Count: 15
Rotatable Bond Count: 1
Complexity: 262
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: 3
XLogP3: 1.2
Topological Polar Surface Area: 74.9

Experimental Properties

Color/Form: No data avaiable
Density: 1.2±0.1 g/cm3
Melting Point: No data available
Boiling Point: 382.8±30.0 °C at 760 mmHg
Flash Point: 185.3℃
Refractive Index: 1.595
PSA: 74.92000
LogP: 2.76620
Vapor Pressure: 0.0±0.9 mmHg at 25°C

4-Acetamido-5-nitro-m-xylene Security Information

Signal Word：warning
Hazard Statement： H303+H313+H333
Warning Statement： P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care
Safety Instruction： H303+H313+H333
Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)

4-Acetamido-5-nitro-m-xylene Customs Data

HS CODE：2924299090
Customs Data：

China Customs Code:
2924299090

Overview:

2924299090. Other cyclic amides(Including cyclic carbamates)(Including their derivatives as well as their salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

Declaration elements:

Product Name, component content, use to, packing

Summary:

2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

4-Acetamido-5-nitro-m-xylene Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
TRC	A158498-50mg	4-Acetamido-5-nitro-m-xylene	606-38-2		50mg	$ 50.00	2022-06-08
TRC	A158498-100mg	4-Acetamido-5-nitro-m-xylene	606-38-2		100mg	$ 65.00	2022-06-08
TRC	A158498-500mg	4-Acetamido-5-nitro-m-xylene	606-38-2		500mg	$ 80.00	2022-06-08
Alichem	A019112012-5g	N-(2,4-Dimethyl-6-nitrophenyl)acetamide	606-38-2	95%	5g	$196.00	2023-09-01
Alichem	A019112012-25g	N-(2,4-Dimethyl-6-nitrophenyl)acetamide	606-38-2	95%	25g	$604.99	2023-09-01
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.	D851413-5g	4-Acetamido-5-nitro-m-xylene	606-38-2	≥97%	5g	915.30	2021-05-17
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.	A93710-1g	N-(2,4-Dimethyl-6-nitrophenyl)acetamide	606-38-2	97%	1g	￥589.0	2021-09-10
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.	A93710-5g	N-(2,4-Dimethyl-6-nitrophenyl)acetamide	606-38-2	97%	5g	￥1539.0	2021-09-10
eNovation Chemicals LLC	D781067-5g	4-Acetamido-5-nitro-m-xylene	606-38-2	>97%	5g	$140	2023-09-02
eNovation Chemicals LLC	D781067-10g	4-Acetamido-5-nitro-m-xylene	606-38-2	>97%	10g	$215	2023-09-02

4-Acetamido-5-nitro-m-xylene Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:606-38-2)4-Acetamido-5-nitro-m-xylene

Order Number:A913600

Stock Status:in Stock

Quantity:25.0g/10.0g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 12:49

Price ($):371.0/191.0

Email:[email protected]

Product Official Link

4-Acetamido-5-nitro-m-xylene Related Literature

1. Enabling stable MnO2 matrix for aqueous zinc-ion battery cathodes?

Yiding Jiao,Liqun Kang,Jasper Berry-Gair,Kit McColl,Jianwei Li,Haobo Dong,Hao Jiang,Ryan Wang,Furio Corà,Dan J. L. Brett,Ivan P. Parkin J. Mater. Chem. A, 2020,8, 22075-22082
2. Fe/S-Catalyzed synthesis of 2-benzoylbenzoxazoles and 2-quinolylbenzoxazoles via redox condensation of o-nitrophenols with acetophenones and methylquinolines?

Thi Thu Tram Nguyen,Thanh Binh Nguyen Org. Biomol. Chem., 2021,19, 6015-6020
3. Embedding heteroatoms: an effective approach to create porphyrin-based functional materials

Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
4. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field

XuxinCheng,XiaomingChen,PengyuanFan
5. Fe(iii)-mediated isomerization of α,α-diarylallylic alcohols to ketones via radical 1,2-aryl migration?

Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755

Related Categories

Additional information on 4-Acetamido-5-nitro-m-xylene

4-Acetamido-5-Nitro-m-Xylene: A Comprehensive Overview

4-Acetamido-5-nitro-m-xylene, also known by its CAS registry number CAS No. 606-38-2, is a chemical compound that has garnered significant attention in various scientific and industrial applications. This compound is a derivative of m-xylene, with specific functional groups attached at the 4 and 5 positions. The presence of an acetamido group (-NHCOCH3) and a nitro group (-NO2) imparts unique chemical properties, making it a versatile molecule for research and development.

The structural configuration of 4-acetamido-5-nitro-m-xylene plays a crucial role in its reactivity and functionality. The acetamido group is known for its ability to participate in hydrogen bonding, which can influence the solubility and stability of the compound. On the other hand, the nitro group is highly electron-withdrawing, which can enhance the electrophilic character of the aromatic ring. This combination makes the compound suitable for various reactions, including nucleophilic aromatic substitution and condensation reactions.

Recent studies have highlighted the potential of 4-acetamido-5-nitro-m-xylene in the field of pharmaceutical chemistry. Researchers have explored its role as a precursor in the synthesis of bioactive compounds, particularly those with anti-inflammatory and antimicrobial properties. The nitro group, being a good leaving group under certain conditions, facilitates the introduction of other functional groups, enabling the creation of diverse drug candidates.

In addition to its pharmaceutical applications, CAS No. 606-38-2 has found utility in materials science. The compound has been investigated as a building block for advanced polymers and coatings. Its ability to undergo polymerization under specific conditions makes it a valuable component in the development of high-performance materials with tailored properties such as thermal stability and mechanical strength.

The synthesis of 4-acetamido-5-nitro-m-xylene typically involves multi-step processes that require precise control over reaction conditions. One common approach involves the nitration of m-xylene followed by acetylation at specific positions. Recent advancements in catalytic methods have improved the efficiency and selectivity of these reactions, reducing production costs and minimizing environmental impact.

From an environmental perspective, understanding the fate and transport of CAS No. 606-38-2 in natural systems is critical. Studies have shown that the compound exhibits moderate biodegradability under aerobic conditions, with microbial communities playing a key role in its transformation. However, further research is needed to assess its long-term ecological effects and develop strategies for safe disposal.

In conclusion, 4-acetamido-5-nitro-m-xylene (CAS No. 606-38-2) is a multifaceted compound with promising applications across various industries. Its unique chemical properties, combined with recent advancements in synthesis and application techniques, position it as a valuable tool for scientists and engineers alike. As research continues to uncover new potentials for this compound, its role in driving innovation will undoubtedly expand further.

606-38-2 (4-Acetamido-5-nitro-m-xylene) Related Products

Recommended suppliers