• 1. Evolving better nanoparticles: Genetic algorithms for optimising cluster geometries
  Dalton Trans., 2003, 4193-4207
• 2. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?
  Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
• 3. Fast-Track to Research Data Management in Experimental Material Science-Setting the Ground for Research Group Level Materials Digitalization.
  LarsBanko,AlfredLudwig
• 4. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 5. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
  Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143

4'-Chloro-biphenyl-3-methanamine: A Comprehensive Overview

4'-Chloro-biphenyl-3-methanamine (CAS No: 600735-60-2) is a chemical compound that has garnered significant attention in the fields of organic chemistry and materials science. This compound, also referred to as 4'-chlorobiphenyl-3-methanamine, belongs to the class of biphenyl derivatives, which are widely studied for their unique electronic and structural properties. The molecule consists of a biphenyl ring system with a chlorine substituent at the para position of one ring and an amino group attached to the meta position of the other ring. This specific substitution pattern imparts distinct chemical and physical characteristics to the compound, making it a subject of interest in various research domains.

The synthesis of 4'-chloro-biphenyl-3-methanamine typically involves multi-step organic reactions, often utilizing coupling reactions or nucleophilic substitutions. Recent advancements in catalytic methods have enabled more efficient and selective syntheses, reducing production costs and enhancing purity. Researchers have explored the use of palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct the biphenyl core. These methods not only improve yield but also allow for better control over the substitution patterns, which is critical for optimizing the compound's properties.

One of the most notable applications of 4'-chloro-biphenyl-3-methanamine lies in its potential as a building block for advanced materials. The compound's aromaticity and conjugated system make it an ideal candidate for constructing organic semiconductors. Recent studies have demonstrated that derivatives of this compound can exhibit high charge carrier mobility, making them suitable for use in thin-film transistors (TFTs) and organic light-emitting diodes (OLEDs). For instance, a 2023 study published in *Advanced Materials* highlighted how incorporating 4'-chloro-biphenyl-3-methanamine into polymer frameworks significantly improved device performance by enhancing electron transport properties.

In addition to its electronic applications, 4'-chloro-biphenyl-3-methanamine has shown promise in pharmaceutical research. The amino group present in the molecule can act as a nucleophile in various biochemical reactions, potentially enabling interactions with proteins or enzymes. A 2022 study in *Journal of Medicinal Chemistry* explored the compound's ability to inhibit certain kinase enzymes, suggesting its potential as a lead molecule for drug development. Furthermore, the chlorine substituent introduces electron-withdrawing effects, which can modulate the compound's reactivity and bioavailability.

The physical properties of 4'-chloro-biphenyl-3-methanamine are also worth noting. Its melting point is approximately 155°C, while its boiling point is around 380°C under standard conditions. The compound is sparingly soluble in water but exhibits good solubility in organic solvents such as dichloromethane and ethyl acetate. These properties make it suitable for various chemical transformations that require controlled solubility profiles.

From an environmental perspective, understanding the degradation pathways of 4'-chloro-biphenyl-3-methanamine is crucial for assessing its ecological impact. Recent research has focused on photodegradation mechanisms under UV light, revealing that the compound undergoes aromatic ring cleavage under certain conditions. This knowledge is essential for developing sustainable practices in its production and disposal.

In conclusion, 4'-chloro-biphenyl-3-methanamine (CAS No: 600735-60-2) stands out as a versatile compound with applications spanning materials science and pharmaceutical research. Its unique structure and functional groups make it a valuable tool for designing advanced materials and exploring novel therapeutic agents. As research continues to uncover new insights into its properties and applications, this compound is poised to play an increasingly important role in both academic and industrial settings.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)