Cas no 600-92-0 (20b-Hydroxy Prednisone)
20β-Hydroxy Prednisone is a synthetic corticosteroid derivative characterized by the hydroxylation of prednisone at the 20β position. This structural modification enhances its metabolic stability and alters its glucocorticoid activity profile, making it a valuable intermediate in steroid synthesis and pharmacological research. The compound exhibits potential applications in studying glucocorticoid receptor interactions and metabolic pathways due to its distinct biochemical properties. Its well-defined structure allows for precise investigations into steroid hormone mechanisms, offering insights into anti-inflammatory and immunosuppressive effects. 20β-Hydroxy Prednisone is commonly utilized in analytical and research settings, where high purity and structural specificity are critical.
20b-Hydroxy Prednisone structure
Product Name:20b-Hydroxy Prednisone
CAS No:600-92-0
MF:C21H28O5
MW:360.444026947021
CID:890189
PubChem ID:71749279
Update Time:2025-06-07
20b-Hydroxy Prednisone Chemical and Physical Properties
Names and Identifiers
-
- 1,4-PREGNADIEN-17,20-BETA, 21-TRIOL-3,11-DIONE
- 20β-Hydroxy Prednisone
- (8S,9S,10R,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-17-hydroxy-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
- 17,20,21-trihydroxypregna-1,4-diene-3,11-dione
- A-Hydroxy Adasone
- A-Hydroxy Ancortone
- A-Hydroxy Bicortone
- A-Hydroxy Prednicorm
- A-Hydroxy Prednicort
- A-Hydroxy Prednisone
- A-Hydroxy Retrocortine
- A-Hydroxy Sone
- A-Hydroxy Ultracorten
- 20b-Hydroxy Prednisone
- DTXSID20857831
- (20R)-17,20,21-Trihydroxypregna-1,4-diene-3,11-dione
- 20alpha-Dihydro-prednisone (M-V)
- (1R,3aS,3bS,9aR,9bS,11aS)-1-[(1R)-1,2-dihydroxyethyl]-1-hydroxy-9a,11a-dimethyl-2,3,3a,3b,4,5,9a,9b,11,11a-decahydro-1H-cyclopenta[a]phenanthrene-7,10-dione
- CHEBI:182969
- (20R)-hydroxyprednisone
- 600-92-0
- 20alpha-dihydro-prednisone
- 20?-Hydroxy Prednisone
- 20alpha-Dihydroprednisone
-
- Inchi: 1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,17-18,22,25-26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,17+,18+,19-,20-,21-/m0/s1
- InChI Key: UMAIDVARGWSZLM-GNIMZFFESA-N
- SMILES: O[C@]1([C@@H](CO)O)CC[C@H]2[C@@H]3CCC4=CC(C=C[C@]4(C)[C@H]3C(C[C@@]21C)=O)=O
Computed Properties
- Exact Mass: 360.19400
- Monoisotopic Mass: 360.19367399g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 26
- Rotatable Bond Count: 2
- Complexity: 724
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 7
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.2
- Topological Polar Surface Area: 94.8?2
Experimental Properties
- PSA: 94.83000
- LogP: 1.55760
20b-Hydroxy Prednisone Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | H952295-5mg |
20b-Hydroxy Prednisone |
600-92-0 | 5mg |
$ 238.00 | 2023-09-07 | ||
| TRC | H952295-50mg |
20b-Hydroxy Prednisone |
600-92-0 | 50mg |
$ 1793.00 | 2023-09-07 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-471504-5 mg |
20β-Hydroxy prednisone, |
600-92-0 | 5mg |
¥2,708.00 | 2023-07-11 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-471504-5mg |
20β-Hydroxy prednisone, |
600-92-0 | 5mg |
¥2708.00 | 2023-09-05 | ||
| A2B Chem LLC | AG72240-5mg |
1,4-PREGNADIEN-17,20-BETA, 21-TRIOL-3,11-DIONE |
600-92-0 | 5mg |
$349.00 | 2024-04-19 | ||
| A2B Chem LLC | AG72240-50mg |
1,4-PREGNADIEN-17,20-BETA, 21-TRIOL-3,11-DIONE |
600-92-0 | 50mg |
$1838.00 | 2024-04-19 |
20b-Hydroxy Prednisone Related Literature
-
Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
-
Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
-
Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
-
Chen Long,Ying Dai,Jianwei Li,Hao Jin Nanoscale, 2020,12, 21124-21130
-
Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
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